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- Pharmacology For Beta Carotene + Vitamins
Beta Carotene + Vitamins Pharmacology
Beta Carotene + Vitamins
About Beta Carotene + VitaminsN/AMechanism of Action of Beta Carotene + VitaminsN/APharmacokinets of Beta Carotene + VitaminsN/AOnset of Action for Beta Carotene + VitaminsN/ADuration of Action for Beta Carotene + VitaminsN/AHalf Life of Beta Carotene + VitaminsN/ASide Effects of Beta Carotene + VitaminsN/AContra-indications of Beta Carotene + VitaminsN/ASpecial Precautions while taking Beta Carotene + VitaminsN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Beta Carotene + Vitamins1.Antioxidant
2.Vitamin deficiency
Interactions for Beta Carotene + VitaminsN/ATypical Dosage for Beta Carotene + VitaminsOne capsule / daySchedule of Beta Carotene + VitaminsN/AStorage Requirements for Beta Carotene + VitaminsN/AEffects of Missed Dosage of Beta Carotene + VitaminsN/AEffects of Overdose of Beta Carotene + VitaminsN/ABeta Carotene
About Beta CaroteneA natural precursor to Vitamin A.Mechanism of Action of Beta CaroteneBeta-carotene acts as the precursor of Vitamin A and in the body it is converted in to Vitamin A. Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.Pharmacokinets of Beta CaroteneAbsorption: Completely absorbed normally. Steatorrhoea, bile deficiency, and protein poor diet adversely affects the absorption and absorption requires bile salts, pancreatic lipase, and dietary fat.
Distribution: Stored primarily as palmitate in kupffer`s cells in liver. Circulates in the form of specific alpha-1 protein; retinol binding protein and transported to cellular retinol binding protein of target cells.
Metabolism: Metabolized in the liver.
Excretion: Excreted mainly through bile and a small amount is excreted through urine.
Onset of Action for Beta CaroteneN/ADuration of Action for Beta CaroteneN/AHalf Life of Beta CaroteneN/ASide Effects of Beta CaroteneAdverse effects occurs only with higher doses and toxicity
1. Nausea
2. Vomiting
3. Itching
4. Dermatitis
5. Exfoliation
6. Alopecia
7. Bone and joint pain
8. Anorexia
9. Irritability
10. Increased intracranial pressure
11. Hepatic impairment
12. Anaphylactic shock
Contra-indications of Beta Carotene1. Hypervitaminosis A
2. Hypersensitivity to Beta Carotene
Special Precautions while taking Beta Carotene1. Oral form should not use in patients with malabsorption syndrome.
2. In inadequate bile secretion oral route may be used with concurrent administration of bile salts.
3. I. V. route is contraindicated except for special water miscible forms intended for infusion with large parenteral volumes and should not use I. V. push of vitamin A of any type.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Beta Carotene1. Vitamin A deficiency
2. Xerophthalmia
3. Acne
4. Ichthyosis
5. Bitot`s spots
6. Night blindness
Interactions for Beta CaroteneCholestyramine: Absorption of Vitamin A is reduced due to reduced availability of fat stabilizing bile salts.
Mineral oil: Interferes with intestinal absorption of Vitamin A.
Oral Contraceptives: Plasma Vitamin A levels are significantly increased.Typical Dosage for Beta CaroteneSevere vitamin A deficiency with xerophthalmia: 500000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Severe vitamin A deficiency: 100000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Children: 5000 to 10000 IU daily for 14 days.
Schedule of Beta CaroteneC1 (Oral)
C (Parenteral)
Storage Requirements for Beta CaroteneStore in a well closed, airtight container in a cool dry place.Effects of Missed Dosage of Beta CaroteneTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Beta CaroteneDiscontinue the vitamin A if hypercalcaemia persists and administer I.V. saline, prednisolone, and calcitonin if required. Monitor hepatic function tests to detect liver damage. Vitamins
About VitaminsVitamins are substances that are found in foods we eat. The term vitamin is derived from the words vital and amine, because vitamins are required for life and were originally thought to be amines. All vitamins are not amines. Vitamins are different in their chemistry, but they all are organic nutrients that are necessary in small amounts for normal metabolism and good health. Most vitamins must be provided by the diet or by supplements; only three vitamins (D, K, and the B vitamin biotin) can be manufactured in the body from non dietary sources. Vitamins are not sources of energy as are carbohydrates, fats, and proteins. Instead, vitamins serve as chemical partners for the enzymes involved in the body`s metabolism, cell production, tissue repair, and other vital processes. Vitamins serve crucial functions in almost all bodily processes example immune, hormonal and nervous systems.
In humans there are thirteen vitamins, divided into two groups. They are fat soluble and water soluble. Fat-soluble vitamins are stored in the fat tissues in your body and in your liver. They go and wait around in your body fat until your body needs them. Water-soluble vitamins are different. Water-soluble vitamins, the vitamins don`t get stored as much in body. Instead, they travel through bloodstream comes out when urinate if body don`t used it.
In humans there are thirteen vitamins, divided into two groups; four fat-soluble vitamins (A, D, E and K), and nine water-soluble vitamins (eight B vitamins and vitamin C).
Mechanism of Action of VitaminsN/APharmacokinets of VitaminsN/AOnset of Action for VitaminsN/ADuration of Action for VitaminsN/AHalf Life of VitaminsN/ASide Effects of VitaminsN/AContra-indications of VitaminsN/ASpecial Precautions while taking VitaminsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for VitaminsN/AInteractions for VitaminsN/ATypical Dosage for VitaminsN/ASchedule of VitaminsN/AStorage Requirements for VitaminsN/AEffects of Missed Dosage of VitaminsN/AEffects of Overdose of VitaminsN/AHome Delivery for Beta Carotene + Vitamins in Your City
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