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- Pharmacology For Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + Boron
Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + Boron Pharmacology
Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + Boron
About Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AMechanism of Action of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/APharmacokinets of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AOnset of Action for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/ADuration of Action for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AHalf Life of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/ASide Effects of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AContra-indications of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/ASpecial Precautions while taking Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/APregnancy Related InformationContraindicated; Iodine is contraindicated in pregnancy. So the combination generic is contraindicated in pregnancy.Old Age Related InformationN/ABreast Feeding Related InformationContraindicated; Iodine is contraindicated in lactation. So the combination generic is contraindicated in breast feeding mother.Children Related InformationN/AIndications for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + Boron1.Antioxidant
2.Vitamin deficiency
3.Mineral deficiency
4.Iron deficiency
Interactions for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/ATypical Dosage for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronOne tablet / daySchedule of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AStorage Requirements for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AEffects of Missed Dosage of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/AEffects of Overdose of Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + BoronN/ABeta Carotene
About Beta CaroteneA natural precursor to Vitamin A.Mechanism of Action of Beta CaroteneBeta-carotene acts as the precursor of Vitamin A and in the body it is converted in to Vitamin A. Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.Pharmacokinets of Beta CaroteneAbsorption: Completely absorbed normally. Steatorrhoea, bile deficiency, and protein poor diet adversely affects the absorption and absorption requires bile salts, pancreatic lipase, and dietary fat.
Distribution: Stored primarily as palmitate in kupffer`s cells in liver. Circulates in the form of specific alpha-1 protein; retinol binding protein and transported to cellular retinol binding protein of target cells.
Metabolism: Metabolized in the liver.
Excretion: Excreted mainly through bile and a small amount is excreted through urine.
Onset of Action for Beta CaroteneN/ADuration of Action for Beta CaroteneN/AHalf Life of Beta CaroteneN/ASide Effects of Beta CaroteneAdverse effects occurs only with higher doses and toxicity
1. Nausea
2. Vomiting
3. Itching
4. Dermatitis
5. Exfoliation
6. Alopecia
7. Bone and joint pain
8. Anorexia
9. Irritability
10. Increased intracranial pressure
11. Hepatic impairment
12. Anaphylactic shock
Contra-indications of Beta Carotene1. Hypervitaminosis A
2. Hypersensitivity to Beta Carotene
Special Precautions while taking Beta Carotene1. Oral form should not use in patients with malabsorption syndrome.
2. In inadequate bile secretion oral route may be used with concurrent administration of bile salts.
3. I. V. route is contraindicated except for special water miscible forms intended for infusion with large parenteral volumes and should not use I. V. push of vitamin A of any type.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Beta Carotene1. Vitamin A deficiency
2. Xerophthalmia
3. Acne
4. Ichthyosis
5. Bitot`s spots
6. Night blindness
Interactions for Beta CaroteneCholestyramine: Absorption of Vitamin A is reduced due to reduced availability of fat stabilizing bile salts.
Mineral oil: Interferes with intestinal absorption of Vitamin A.
Oral Contraceptives: Plasma Vitamin A levels are significantly increased.Typical Dosage for Beta CaroteneSevere vitamin A deficiency with xerophthalmia: 500000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Severe vitamin A deficiency: 100000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Children: 5000 to 10000 IU daily for 14 days.
Schedule of Beta CaroteneC1 (Oral)
C (Parenteral)
Storage Requirements for Beta CaroteneStore in a well closed, airtight container in a cool dry place.Effects of Missed Dosage of Beta CaroteneTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Beta CaroteneDiscontinue the vitamin A if hypercalcaemia persists and administer I.V. saline, prednisolone, and calcitonin if required. Monitor hepatic function tests to detect liver damage. Minerals
About MineralsDietary mineral supplement, Nutritional supplement.Mechanism of Action of MineralsN/APharmacokinets of MineralsN/AOnset of Action for MineralsN/ADuration of Action for MineralsN/AHalf Life of MineralsN/ASide Effects of MineralsN/AContra-indications of MineralsN/ASpecial Precautions while taking MineralsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for MineralsN/AInteractions for MineralsN/ATypical Dosage for MineralsN/ASchedule of MineralsN/AStorage Requirements for MineralsN/AEffects of Missed Dosage of MineralsN/AEffects of Overdose of MineralsN/AMultivitamins
About MultivitaminsDietary supplement, Vitamins.Mechanism of Action of MultivitaminsN/APharmacokinets of MultivitaminsN/AOnset of Action for MultivitaminsN/ADuration of Action for MultivitaminsN/AHalf Life of MultivitaminsN/ASide Effects of MultivitaminsN/AContra-indications of MultivitaminsN/ASpecial Precautions while taking MultivitaminsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for MultivitaminsN/AInteractions for MultivitaminsN/ATypical Dosage for MultivitaminsN/ASchedule of MultivitaminsN/AStorage Requirements for MultivitaminsN/AEffects of Missed Dosage of MultivitaminsN/AEffects of Overdose of MultivitaminsN/AIron (Carbonyl Iron)
About Iron (Carbonyl Iron)A highly pure, nontoxic Iron(a minimum 98% iron content), Iron dietary supplement and to treat iron deficiency.Mechanism of Action of Iron (Carbonyl Iron)Iron formulations exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Pharmacokinets of Iron (Carbonyl Iron)Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed.
Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin.
Metabolism: Iron liberated by destruction of haemoglobin is reused by the body.
Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.
Onset of Action for Iron (Carbonyl Iron)4 daysDuration of Action for Iron (Carbonyl Iron)2 to 4 monthsHalf Life of Iron (Carbonyl Iron)N/ASide Effects of Iron (Carbonyl Iron)1. Nausea
2. Epigasttric distress
3. Vomiting
4. Constipation
5. Diarrhoea
6. Black stools
7. Temporary staining of teeth with liquid formulations
Contra-indications of Iron (Carbonyl Iron)1. Haemolytic anaemia unless iron deficiency anaemia is also present
2. Haemochromatosis
3. Haemosiderosis
4. Peptic ulcer
5. Regional enteritis
6. Ulcerative colitis
7. Those receiving repeated blood transfusions
Special Precautions while taking Iron (Carbonyl Iron)1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related InformationMay be usedOld Age Related InformationUse with cautionBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Iron (Carbonyl Iron)1. Iron deficiency
2. Iron deficiency during pregnancy and lactation
3. Iron deficiency in infants and children
Interactions for Iron (Carbonyl Iron)(Oral Iron): Antacids: GI absorption of iron reduced.
Ascorbic acid: GI absorption of iron enhanced.
Chloramphenicol: Serum iron levels may be increased.
Cimetidine: GI absorption may be reduced.
Levodopa: Decreased levodopa serum levels.
Methyldopa: May result in decreased efficacy of methyldopa.
Quinolones: GI absorption of quinolones decreased.
Penicillamine: Marked reduction in GI absorption of penicillamine.
Tetracyclines: Decrease in the absorption of both tetracyclines and iron salts.
Food: Eggs and milk inhibit iron absorption. Administration of calcium and iron supplementation with food reduces ferrous sulfate absorption by one-third. If combined iron and calcium supplementation required then calcium carbonate should be used and the supplementation taken between meals.
Typical Dosage for Iron (Carbonyl Iron)Oral:
Ferrous fumarate:
Adults: Starts with 50 to 100mg 2 to 3 times daily. Adjust the dosage based on patient`s response.
Children: 4 to 6mg/kg daily in three divided doses.
Ferrous sulphate:
Adults: 100 to 300mg; twice daily. Increases the dosage based on patient`s response if required up to 300mg 4 times daily.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Ferrous gluconate:
300 to 1200mg daily in three to four divided doses.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Schedule of Iron (Carbonyl Iron)HStorage Requirements for Iron (Carbonyl Iron)Store in a well closed container in a cool dry place. Protect from light.Effects of Missed Dosage of Iron (Carbonyl Iron)Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Iron (Carbonyl Iron)Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl. Iodine
About IodineEssential trace element, fastest acting thyroid inhibitor, Antithyroid agent.Mechanism of Action of IodineIt is the fastest acting thyroid inhibitor which inhibits hormone release. It reduced to iodide response to both iodine and iodides are identical. Endocytosis of colloid and proteolysis of thyroglobulin comes to a halt. It has a direct action on thyroid cells and also attenuate TSH and cyclic AMP induced thyroid stimulation. Excess iodide inhibits it`s on transport in thyroid cells and alter the redox potential of cells; thus interfering with iodination and reduces T3 or T4 synthesis. The gland if enlarged; shrinks, becomes firm and less vascular. The thyroid status returns to normal at a faster rate.Pharmacokinets of IodineAbsorption: Well absorbed orally.
Distribution: Widely distributed in the body and also crosses the placenta.
Onset of Action for IodineN/ADuration of Action for IodineN/AHalf Life of IodineN/ASide Effects of Iodine1. Fever
2. Angioedema
3. Swelling of lips and eyelids
4. Arthralgia
5. Thrombocytopenia
6. Salivation
7. Sneezing
8. Lymphadenopathy
9. Petechial haemorrhage.
10. Burning sensation in mouth
11. Headache
12. Rashes
13. Flaring of acne
Contra-indications of Iodine1. Hypersensitivity to the drugSpecial Precautions while taking Iodine1. Long term therapy with high dosePregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Iodine1. Hyperthyroidism
2. Hypothyroidism
3. Prior to thyroidectomy
4. Prophylaxis of endemic goiter
Interactions for IodineN/ATypical Dosage for IodineOral: 5 to 10ml in water 8th hourly.Schedule of IodineHStorage Requirements for IodineStore in a well closed container and protects from light.Effects of Missed Dosage of IodineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of IodineProvide symptomatic treatment and supportive measures.
Boron
About BoronMicronutrient, Dietary mineral.Mechanism of Action of BoronN/APharmacokinets of BoronN/AOnset of Action for BoronN/ADuration of Action for BoronN/AHalf Life of BoronN/ASide Effects of BoronN/AContra-indications of BoronN/ASpecial Precautions while taking BoronN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for BoronN/AInteractions for BoronN/ATypical Dosage for BoronN/ASchedule of BoronN/AStorage Requirements for BoronN/AEffects of Missed Dosage of BoronN/AEffects of Overdose of BoronN/AHome Delivery for Beta Carotene + Minerals + Multivitamins + Iron (Carbonyl Iron) + Iodine + Boron in Your City
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