Zinc + Vitamin B-Complex + Vitamin C + Vitamin E Pharmacology

Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

About Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Mechanism of Action of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Pharmacokinets of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Onset of Action for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Duration of Action for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Half Life of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Side Effects of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Contra-indications of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Special Precautions while taking Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Interactions for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Typical Dosage for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Schedule of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Storage Requirements for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Effects of Missed Dosage of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Effects of Overdose of Zinc + Vitamin B-Complex + Vitamin C + Vitamin E

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Zinc

About Zinc

Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.

Mechanism of Action of Zinc

Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.

Pharmacokinets of Zinc

Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.

Onset of Action for Zinc

N/A

Duration of Action for Zinc

N/A

Half Life of Zinc

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Side Effects of Zinc

1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes

Contra-indications of Zinc

N/A

Special Precautions while taking Zinc

1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information

Use with caution

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Zinc

1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia

Interactions for Zinc

Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc

Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.

Schedule of Zinc

N/A

Storage Requirements for Zinc

Store at a temperature below 30 degree C

Effects of Missed Dosage of Zinc

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Zinc

Provide symptomatic treatment and supportive measures

Vitamin B-Complex

About Vitamin B-Complex

Vitamin B-complex are group of vitamins, which include Thiamine (B1),Riboflavin (B2),Niacin (B3),Pantothenic acid (B5),Pyridoxine (B6),Cyanocobalamin (B12),Folic acid and Biotin.
These vitamins are essential for the breakdown of carbohydrates into glucose (this provides energy for the body),the breakdown of fats and proteins (which aids the normal functioning of the nervous system),muscle tone in the stomach and intestinal tract,Skin,Hair,Eyes,Mouth and Liver

Mechanism of Action of Vitamin B-Complex

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Pharmacokinets of Vitamin B-Complex

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Onset of Action for Vitamin B-Complex

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Duration of Action for Vitamin B-Complex

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Half Life of Vitamin B-Complex

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Side Effects of Vitamin B-Complex

1.Drowsiness
2.Headache
3.Diarrhoea
4.Nausea.
5.Numbness of the skin

Contra-indications of Vitamin B-Complex

Hypersensitivity to the ingredient of Vitamin B-complex

Special Precautions while taking Vitamin B-Complex

1.Pernecious anaemia
2.Patient receiving dialysis

Pregnancy Related Information

May be used.

Old Age Related Information

May be used.

Breast Feeding Related Information

May be used.

Children Related Information

May be used.

Indications for Vitamin B-Complex

1.Vitamin deficiency states
2. As an adjuvant to antibiotic therapy
3. Combinations with lactobacillus are indicated in aphthous stomatitis, thrush.

Interactions for Vitamin B-Complex

Sulfinpyrazone: Uricosuric effect of sulfinpyrazone may be inhibited by niacin.
Levodopa: Pyridoxine reduces efficacy of levodopa. Avoid supplemental vitamins that contain greater then 5 mg pyridoxine in the daily dose.
Phenobarbital: Serum levels of Phenobarbital may be decreased if used concomitantly with pyridoxine.
Phenytoin: Pyridoxine decreases serum levels of phenytoin.
Dapsone: PABA antagonizes anti-malarial effect of dapsone.

Typical Dosage for Vitamin B-Complex

I tablet /day

Schedule of Vitamin B-Complex

N/A

Storage Requirements for Vitamin B-Complex

Store at room temperature. Keep out of the reach of children.Protect from heat, light and moisture.

Effects of Missed Dosage of Vitamin B-Complex

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule. Do not double the dose.

Effects of Overdose of Vitamin B-Complex

Give supportive measures and symptomatic treatment.

Vitamin C

About Vitamin C

Water soluble vitamin, antioxidant.

Mechanism of Action of Vitamin C

Vitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.

Pharmacokinets of Vitamin C

Absorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.

Onset of Action for Vitamin C

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Duration of Action for Vitamin C

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Half Life of Vitamin C

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Side Effects of Vitamin C

1. Discomfort at injection site
2. Acid urine
3. Renal calculi
4. Oxaluria

Contra-indications of Vitamin C

No known contraindications

Special Precautions while taking Vitamin C

1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

May be used

Indications for Vitamin C

1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries

Interactions for Vitamin C

Oral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.

Typical Dosage for Vitamin C

Oral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Scurvy:
Oral:
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.

Schedule of Vitamin C

C1 (Oral)
C (Parenteral)

Storage Requirements for Vitamin C

Store in a cool dry area in a well closed container. Protects from moisture, light and direct heat.

Effects of Missed Dosage of Vitamin C

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Vitamin C

Discontinue the therapy and provide symptomatic and supportive measures.

Vitamin E

About Vitamin E

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Mechanism of Action of Vitamin E

Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.

Pharmacokinets of Vitamin E

Absorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.

Onset of Action for Vitamin E

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Duration of Action for Vitamin E

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Half Life of Vitamin E

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Side Effects of Vitamin E

1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence

Contra-indications of Vitamin E

1. Hypersensitivity to the drug
2. Should not administer intravenously

Special Precautions while taking Vitamin E

1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens

Pregnancy Related Information

May be used

Old Age Related Information

N/A

Breast Feeding Related Information

May be used

Children Related Information

N/A

Indications for Vitamin E

1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant

Interactions for Vitamin E

Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.

Typical Dosage for Vitamin E

Oral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.

Schedule of Vitamin E

Storage Requirements for Vitamin E

Store in a well closed container in a cool dry place. Protect from light.

Effects of Missed Dosage of Vitamin E

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Vitamin E

Provide supportive measures and symptomatic treatment.

Home Delivery for Zinc + Vitamin B-Complex + Vitamin C + Vitamin E in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for zinc + vitamin b-complex + vitamin c + vitamin e and other medicines and health products. Home delivery services for zinc + vitamin b-complex + vitamin c + vitamin e may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

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Zinc + Vitamin B-Complex + Vitamin C + Vitamin E is a generic medicine name and there are several brands available for it. Some of the brands for zinc + vitamin b-complex + vitamin c + vitamin e might be better known than zinc + vitamin b-complex + vitamin c + vitamin e itself. If the pharmacy that's willing to deliver medicines to your home doesn't have zinc + vitamin b-complex + vitamin c + vitamin e in stock, you can ask for one of the branded alternatives for zinc + vitamin b-complex + vitamin c + vitamin e.