Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein Pharmacology

Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

About Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Mechanism of Action of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Pharmacokinets of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Onset of Action for Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Duration of Action for Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Half Life of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Side Effects of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Contra-indications of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Special Precautions while taking Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Interactions for Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Typical Dosage for Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Schedule of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Storage Requirements for Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Effects of Missed Dosage of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Effects of Overdose of Iron ammonium citrate + Calcium + Magnesium + Manganese + Zinc + Protein

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Iron ammonium citrate

About Iron ammonium citrate

Oral iron preparation, Antianemic,hematinic

Mechanism of Action of Iron ammonium citrate

Iron Ammonium Citrate contains 16.5% and 18.5% of iron. It exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues. Iron ammonium citrate is given by mouth as a source of iron for iron-deficiency anaemia.

Pharmacokinets of Iron ammonium citrate

harmaco Kinetic
Absorption: Ferric is converted into Ferrous form and it is absorbed in ferrous form. It is poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed. Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin. Metabolism: Iron liberated by destruction of haemoglobin is reused by the body. Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.

Onset of Action for Iron ammonium citrate

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Duration of Action for Iron ammonium citrate

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Half Life of Iron ammonium citrate

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Side Effects of Iron ammonium citrate

1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations.

Contra-indications of Iron ammonium citrate

1.Haemolytic anaemia unless iron deficiency anaemia is also present
2.Haemochromatosis
3.Haemosiderosis
4.Peptic ulcer
5.Regional enteritis
6.Ulcerative colitis
7.Those receiving repeated blood transfusions

Special Precautions while taking Iron ammonium citrate

1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients

Pregnancy Related Information

May be used

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Iron ammonium citrate

1. Iron deficiency
2. Iron deficiency anaemia

Interactions for Iron ammonium citrate

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Typical Dosage for Iron ammonium citrate

Adult: I capsule or 15ml twice daily after meals.
Children: 5 ml twice daily after meals.

Schedule of Iron ammonium citrate

Storage Requirements for Iron ammonium citrate

Store in a well closed container in a cool dry place. Protect from light.

Effects of Missed Dosage of Iron ammonium citrate

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Iron ammonium citrate

Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

Calcium

About Calcium

Calcium is necessary for cardiac function, muscle contraction, nervous activity, coagulation of blood and for maintaining structural integrity of cell membranes.
Plasma concentration of calcium is kept in normal range by three endocrine factors which control metabolism of calcium. These are (a) Parathyroid hormone, (b) Calcitonin, (c) Vitamin D. Calcium in plasma is bound to albumin, is complexed with anions (e.g. phosphate) and as diffusible ionic calcium. The physiological effects are exerted by ionic calcium. The predominant source of calcium is dairy products and the daily intake varies from 200 - 2500 mg. Adequate calcium intake is particularly important during periods of bone growth in childhood and adolescence and during pregnancy and lactation.
Patients with advanced renal insufficiency exhibit phosphate retention and some degree of hyperphosphataemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy and soft tissue calcification. Calcium acetate, when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the faeces.
Deficiency signs and symptoms: Osteoporosis, pathological fractures, brittle nails and hair.

Mechanism of Action of Calcium

Calcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and
A-V conduction. Calcium is also required for blood-coagulation.

Pharmacokinets of Calcium

Absorption: Actively absorbed from gastrointestinal tract in an ionized form; and vitamin D in it`s active form is required for calcium absorption, Distribution: Distributed mainly in to skeletal tissue (99%) and 1% is distributed equally between the intracellular and extra cellular fluid. CSF levels are about half of the serum calcium levels, Metabolism: Not significantly metabolized in the body, Excretion: Excreted mainly through faeces and a small amount is excreted through urine.

Onset of Action for Calcium

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Duration of Action for Calcium

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Half Life of Calcium

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Side Effects of Calcium

1.Constipation
2.Bloating
3.Excess gas
4.Anorexia
5.Nausea
6.Vomiting
7.Abdominal pain
8.Thirst
9.Hypercalcaemia
10.Polyuria
11.Dry mouth
12.Delirium
13.Confusion

Contra-indications of Calcium

1.Renal calculi
2.Hypophosphataemia
3.Hypercalcaemia
4.Ventricular fibrillation.

Special Precautions while taking Calcium

1.Renal impairment
2.Cardiac diseases
3.Sarcoidosis
4.Cor pulmonale
5.Respiratory acidosis
6.Respiratory failure
7.End stage renal failure
8.Hypoparathyroid patients
9.Digitalized patients
10.Prolonged use of therapeutic amounts.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Calcium

1.Hypocalcaemia
2.Calcium and vitamin D deficiency
3.Calcium deficiency during pregnancy and lactation
4.Rickets
5.Prevention of osteoporosis in postmenopausal women
6.Chronic renal failure.

Interactions for Calcium

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Typical Dosage for Calcium

Oral: 500mg to 2g daily in two to four divided doses.
Hypocalcaemia:
Adults: 1g daily. Increases to 2g daily if required.
Prevention of osteoporosis: 1 to 1.5g daily.
Children: 45 to 65mg/kg daily.
Neonates: 50 to 150mg/kg and should not exceed 1g.

Schedule of Calcium

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Storage Requirements for Calcium

Store in a well closed container in a cool and dry place. Protect from light.

Effects of Missed Dosage of Calcium

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Calcium

Remove calcium from stomach by induced emesis and gastric lavage. Provide symptomatic treatment and supportive measures.

Magnesium

About Magnesium

Magnesium is essential for enzyme activity, calcium and potassium uptake, nerve transmission, bone formation and metabolism of carbohydrates and minerals. It is magnesium, not calcium, which helps form hard tooth enamel, resistant to decay. Like calcium and chloride, magnesium also plays a role in regulating the acid-alkaline balance in the body. High magnesium levels in drinking water have been linked to resistance to heart disease. Although it is found in many foods, including dairy products, nuts, vegetables, fish, meat and seafood, deficiencies are common in America due to soil depletion, poor absorption and lack of minerals in drinking water. A diet high in carbohydrates, oxalic acid in foods like raw spinach and phytic acid found in whole grains can cause deficiencies. An excellent source of usable magnesium is beef, chicken or fish broth. High amounts of zinc and vitamin D increase magnesium requirements. Magnesium deficiency can result in coronary heart disease, chronic weight loss, obesity, fatigue, epilepsy and impaired brain function. Chocolate cravings are a sign of magnesium deficiency.

Mechanism of Action of Magnesium

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Pharmacokinets of Magnesium

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Onset of Action for Magnesium

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Duration of Action for Magnesium

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Half Life of Magnesium

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Side Effects of Magnesium

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Contra-indications of Magnesium

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Special Precautions while taking Magnesium

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Magnesium

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Interactions for Magnesium

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Typical Dosage for Magnesium

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Schedule of Magnesium

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Storage Requirements for Magnesium

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Effects of Missed Dosage of Magnesium

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Effects of Overdose of Magnesium

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Manganese

About Manganese

Mechanism of Action of Manganese

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Pharmacokinets of Manganese

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Onset of Action for Manganese

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Duration of Action for Manganese

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Half Life of Manganese

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Side Effects of Manganese

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Contra-indications of Manganese

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Special Precautions while taking Manganese

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Manganese

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Interactions for Manganese

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Typical Dosage for Manganese

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Schedule of Manganese

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Storage Requirements for Manganese

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Effects of Missed Dosage of Manganese

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Effects of Overdose of Manganese

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Zinc

About Zinc

Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.

Mechanism of Action of Zinc

Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.

Pharmacokinets of Zinc

Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.

Onset of Action for Zinc

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Duration of Action for Zinc

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Half Life of Zinc

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Side Effects of Zinc

1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes

Contra-indications of Zinc

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Special Precautions while taking Zinc

1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information

Use with caution

Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Zinc

1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia

Interactions for Zinc

Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc

Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.

Schedule of Zinc

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Storage Requirements for Zinc

Store at a temperature below 30 degree C

Effects of Missed Dosage of Zinc

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Zinc

Provide symptomatic treatment and supportive measures

Protein

About Protein

Nutrient.

Mechanism of Action of Protein

Protein is an essential nutrient for cell maintenance and repair, and regulation of a wide range of bodily functions. Our digestive system breaks down protein to its amino acid constituents. They`re involved in the nervous system, repairing and maintaining tissue such as bones and skin, and bringing energy to cells. Protein is the building block of all life and is essential for the growth of cells and tissue repair. Protein is made up of amino acids.There are 22 amino acids, divided into essential and non-essential amino acids. Essential amino acids must appear in our diet because they cannot be made by the body. The 8 essential amino acids we must eat in our diet include: isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine.

Pharmacokinets of Protein

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Onset of Action for Protein

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Duration of Action for Protein

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Half Life of Protein

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Side Effects of Protein

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Contra-indications of Protein

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Special Precautions while taking Protein

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Protein

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Interactions for Protein

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Typical Dosage for Protein

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Schedule of Protein

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Storage Requirements for Protein

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Effects of Missed Dosage of Protein

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Effects of Overdose of Protein

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