Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc Pharmacology

Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

About Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Mechanism of Action of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Pharmacokinets of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Onset of Action for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Duration of Action for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Half Life of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Side Effects of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Contra-indications of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Special Precautions while taking Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Interactions for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Typical Dosage for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Schedule of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Storage Requirements for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Effects of Missed Dosage of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Effects of Overdose of Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc

N/A

Iron (Ferrous sulphate)

About Iron (Ferrous sulphate)

Oral iron preparation, Antianemic,hematinic.

Mechanism of Action of Iron (Ferrous sulphate)

Ferrous sulfate is used as a source of iron for iron-deficiency anaemia. It is given by mouth; the dried form is often used in solid dosage forms and the heptahydrate in liquid dosage forms. Usual doses of dried ferrous sulfate are up to 600 mg daily (equivalent to 180 to 195 mg of iron daily,).
Ferrous sulfate oxidised with nitric and sulfuric acids yields ferric subsulfate solution, also known as Monsel`s solution, which has been used as a haemostatic. It exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.

Pharmacokinets of Iron (Ferrous sulphate)

Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed. Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin. Metabolism: Iron liberated by destruction of haemoglobin is reused by the body. Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.

Onset of Action for Iron (Ferrous sulphate)

N/A

Duration of Action for Iron (Ferrous sulphate)

N/A

Half Life of Iron (Ferrous sulphate)

N/A

Side Effects of Iron (Ferrous sulphate)

1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations.

Contra-indications of Iron (Ferrous sulphate)

1.Haemolytic anaemia unless iron deficiency anaemia is also present
2.Haemochromatosis
3.Haemosiderosis
4.Peptic ulcer
5.Regional enteritis
6.Ulcerative colitis
7.Those receiving repeated blood transfusions.

Special Precautions while taking Iron (Ferrous sulphate)

1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients

Pregnancy Related Information

May be used

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Iron (Ferrous sulphate)

1. Iron deficiency
2. Iron deficiency anaemia

Interactions for Iron (Ferrous sulphate)

N/A

Typical Dosage for Iron (Ferrous sulphate)

Adults: 100 to 300mg; twice daily. Increases the dosage based on patient`s response if required up to 300mg 4 times daily.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.

Schedule of Iron (Ferrous sulphate)

Storage Requirements for Iron (Ferrous sulphate)

Store in a well closed container in a cool dry place. Protect from light.

Effects of Missed Dosage of Iron (Ferrous sulphate)

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Iron (Ferrous sulphate)

Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

Iron (Ferrous fumarate)

About Iron (Ferrous fumarate)

Iron (II) salt of fumaric acid, Oral iron preparation, Antianemic,hematinic.

Mechanism of Action of Iron (Ferrous fumarate)

Ferrous fumarate is used as a source of iron for iron-deficiency anaemia. It is given by mouth in usual doses of up to 600 mg daily (equivalent to about 200 mg of iron daily). Iron formulations exert haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Ferrous fumarate has similar efficacy as that of Ferrous sulphate.But it is more stable and almost tasteless as compared to Ferrous fumarate and it does not precipitate proteins and does not interfere with enzymes of digestive system.

Pharmacokinets of Iron (Ferrous fumarate)

Onset of Action for Iron (Ferrous fumarate)

N/A

Duration of Action for Iron (Ferrous fumarate)

N/A

Half Life of Iron (Ferrous fumarate)

N/A

Side Effects of Iron (Ferrous fumarate)

1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations.

Contra-indications of Iron (Ferrous fumarate)

Special Precautions while taking Iron (Ferrous fumarate)

Pregnancy Related Information

May be used

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Iron (Ferrous fumarate)

1. Iron deficiency
2. Iron deficiency anaemia

Interactions for Iron (Ferrous fumarate)

N/A

Typical Dosage for Iron (Ferrous fumarate)

Oral:
Adults: Starts with 50 to 100mg 2 to 3 times daily. Adjust the dosage based on patient`s response.
Children: 4 to 6mg/kg daily in three divided doses.

Schedule of Iron (Ferrous fumarate)

Storage Requirements for Iron (Ferrous fumarate)

Store in a well closed container in a cool dry place. Protect from light.

Effects of Missed Dosage of Iron (Ferrous fumarate)

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Iron (Ferrous fumarate)

Vit B6

About Vit B6

Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization.
Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.

Mechanism of Action of Vit B6

Vitamin B6 is a collective term for Pyridoxine, Pyridoxal, Pyridoxamine and their phosphorylated derivatives such as Pyridoxine phosphate, Pyridoxal phosphate and Pyridoxamine derivatives respectively. Vitamin B6 is essential for the metabolism of amino acid, glycogen and fatty acids, for nerve functions, for the formation of red blood cells and also helps the skin healthy. Vitamin B6 is also used for the synthesis of nucleic acid, Haemoglobin, Sphingomyelin, other Sphingolipids, Serotonin, Dopamine, Noradrenaline and GABA.

Pharmacokinets of Vit B6

Absorption: Vitamin B6 is readily absorbed after oral administration.
Distribution: It is mainly distributed in the body in protein bound form. It is stored primarily in the liver and to a lesser extent muscle and brain.
Metabolism: It is metabolised in the liver

Onset of Action for Vit B6

N/A

Duration of Action for Vit B6

N/A

Half Life of Vit B6

15-20 days

Side Effects of Vit B6

1. Neuropathy
2. Unstable gait
3. Drowsiness
4. Perioral numbness
5. Paresthesia
6. Numbness of feet
7. Somnolence
8. Sensory neuropathy
9. Ataxia

Contra-indications of Vit B6

1. Hypersensitivity to Vitamin B6

Special Precautions while taking Vit B6

N/A

Pregnancy Related Information

May be used

Old Age Related Information

May be used

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution
NEONATES: Contraindicated

Indications for Vit B6

1. Vitamin B6 deficiency including inadequate diet and drug induced causes
2. Neuropathy
3. Premenstrual syndrome
4. Hyperoxaluria type 1
5. Metabolic disorder
6. Isoniazid poisoning

Interactions for Vit B6

Cycloserine, Hydralazine, Isoniazide, Oral contraceptive, Penicillamine: Increase Pyridoxine requirement.
Levodopa: Pyridoxine reverses the therapeutic effect of Levodopa.
Phenobarbital, Phenytoin: Pyridoxine decreases serum level of these anticonvulsants.

Typical Dosage for Vit B6

Adult: 10 - 20 mg / day
Dietary deficiency: 2.5 -10 mg / day for effective therapeutic response is obtained.
Maintenance dose: 2 - 5 mg / day for several weeks.
Drug induced deficiency: 100 - 200 mg / day for 3 weeks.
Maintenance dose: 25 - 100 mg / day
Neuropathy: 50 - 200 mg /day
Premenstrual syndrome: 40 - 500 mg / day
Hyperoxaluria type 1: 25 - 300 mg / day
Metabolic disorder: 100-500 mg /day.
Isoniazid poisoning: Initial dose: 1 - 4 g as IV administration, then 1 g IM every 30 minute until Pyridoxine dose is equal to the Isoniazid dose has been given.

Schedule of Vit B6

N/A

Storage Requirements for Vit B6

Store it at 15 - 30 degree C. Protect from moisture and heat.

Effects of Missed Dosage of Vit B6

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Vit B6

Give supportive measures and symptomatic treatment. The signs of Pyridoxine overdose can be resolved by discontinuation (withdrawal) of Pyridoxine.

Folic Acid

About Folic Acid

Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.

Mechanism of Action of Folic Acid

Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.

Pharmacokinets of Folic Acid

Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.

Onset of Action for Folic Acid

Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes

Duration of Action for Folic Acid

Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours

Half Life of Folic Acid

N/A

Side Effects of Folic Acid

N/A

Contra-indications of Folic Acid

N/A

Special Precautions while taking Folic Acid

1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient

Pregnancy Related Information

May be used

Old Age Related Information

May be used

Breast Feeding Related Information

May be used

Children Related Information

May be used

Indications for Folic Acid

1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue

Interactions for Folic Acid

1. Hypersensitivity reactions with injection form
2. Bronchospasm

Typical Dosage for Folic Acid

Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.

Schedule of Folic Acid

C1 (Oral)
C (Parenteral)

Storage Requirements for Folic Acid

Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.

Effects of Missed Dosage of Folic Acid

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Folic Acid

Relatively non toxic. Provide symptomatic treatment and supportive measures.

Zinc

About Zinc

Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.

Mechanism of Action of Zinc

Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.

Pharmacokinets of Zinc

Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.

Onset of Action for Zinc

N/A

Duration of Action for Zinc

N/A

Half Life of Zinc

N/A

Side Effects of Zinc

1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes

Contra-indications of Zinc

N/A

Special Precautions while taking Zinc

1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information

Use with caution

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Zinc

1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia

Interactions for Zinc

Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc

Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.

Schedule of Zinc

N/A

Storage Requirements for Zinc

Store at a temperature below 30 degree C

Effects of Missed Dosage of Zinc

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Zinc

Provide symptomatic treatment and supportive measures

Home Delivery for Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc and other medicines and health products. Home delivery services for iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc before they complete the sale. You can get this information while placing the order for iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc with the pharmacy.

Iron (Ferrous sulphate) + Iron (Ferrous fumarate) + Vit B6 + Folic acid + Zinc is a generic medicine name and there are several brands available for it. Some of the brands for iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc might be better known than iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc in stock, you can ask for one of the branded alternatives for iron (ferrous sulphate) + iron (ferrous fumarate) + vit b6 + folic acid + zinc.