Iron (Ferrous glycine sulphate) Pharmacology

Iron (Ferrous glycine sulphate)

About Iron (Ferrous glycine sulphate)
Oral iron preparation, An iron-containing salt, Antianemic,hematinic
Mechanism of Action of Iron (Ferrous glycine sulphate)
Ferrous glycine sulfate is a chelate of ferrous sulfate and glycine used as a source of iron for iron-deficiency anaemia. It is given by mouth in doses containing the equivalent of up to 150 mg of iron daily. It exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
It has relatively high bioavailability in the presence of dietary inhibitors. Chelates prevent iron from binding to inhibitors in food or precipitating as insoluble ferric hydroxide in the pH of the small intestine.
Pharmacokinets of Iron (Ferrous glycine sulphate)
Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed. Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin. Metabolism: Iron liberated by destruction of haemoglobin is reused by the body. Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.
Onset of Action for Iron (Ferrous glycine sulphate)
N/A
Duration of Action for Iron (Ferrous glycine sulphate)
N/A
Half Life of Iron (Ferrous glycine sulphate)
N/A
Side Effects of Iron (Ferrous glycine sulphate)
1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations
Contra-indications of Iron (Ferrous glycine sulphate)
1.Haemolytic anaemia unless iron deficiency anaemia is also present
2.Haemochromatosis
3.Haemosiderosis
4.Peptic ulcer
5.Regional enteritis
6.Ulcerative colitis
7.Those receiving repeated blood transfusions.
Special Precautions while taking Iron (Ferrous glycine sulphate)
1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
Indications for Iron (Ferrous glycine sulphate)
1. Iron deficiency
2. Iron deficiency anaemia
Interactions for Iron (Ferrous glycine sulphate)
N/A
Typical Dosage for Iron (Ferrous glycine sulphate)
Adult: I capsule or 10ml once or twice daily after meals.
Children: 5-10 ml twice daily after meals.
Schedule of Iron (Ferrous glycine sulphate)
N/A
Storage Requirements for Iron (Ferrous glycine sulphate)
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Iron (Ferrous glycine sulphate)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron (Ferrous glycine sulphate)
Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

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Iron (Ferrous glycine sulphate) is a generic medicine name and there are several brands available for it. Some of the brands for iron (ferrous glycine sulphate) might be better known than iron (ferrous glycine sulphate) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron (ferrous glycine sulphate) in stock, you can ask for one of the branded alternatives for iron (ferrous glycine sulphate).