Filgrastim Pharmacology

Filgrastim

About Filgrastim
A cytokine glycoprotein, a human granulocyte colony-stimulating factor (G-CSF) analog, Immunostimulant.
Mechanism of Action of Filgrastim
Filgrastim is a cytokine glycoprotein that stimulates proliferation, differentiation and functional activity of neutrophils.This will produce a rapid increase in WBC counts.
Pharmacokinets of Filgrastim
Absorption: It is rapidly absorbed after subcutaneous administration.
Onset of Action for Filgrastim
5 - 60 minutes
Duration of Action for Filgrastim
1 - 7 days
Half Life of Filgrastim
3.5 hours
Side Effects of Filgrastim
1.Headache
2.Fatigue
3.Nausea
4.Vomiting
5.Diarrhoea
6.Stomatitis
7.Thrombocytopenia
8.Bone pain
9.Weakness
10.Muscle aches
11.Arrhythmia
12.Skeletal pain
13.Fever
14.Dyspnea
Contra-indications of Filgrastim
1.Hypersensitivity to Filgrastim
Special Precautions while taking Filgrastim
Heart disease
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Filgrastim
1.To decrease incidence of infection after cancer chemotherapy for non myeloid malignancies
2.Chonic severe neutropenia
3.After bone marrow transplantation in cancer patients
4.Agranulocytosis
5.Apastic anaemia
6.Hairy cell leukaemia
Interactions for Filgrastim
N/A
Typical Dosage for Filgrastim
Subcutaneous or Intravenous Injection
Adult:5mcg/kg as single dose if required dose can be increased by 5mcg/kg for each couse of chemotherapy
Schedule of Filgrastim
N/A
Storage Requirements for Filgrastim
Store at refrigerator.Do not freeze. Keep out of the reach of children.
Effects of Missed Dosage of Filgrastim
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.
Effects of Overdose of Filgrastim
Give supportive measures and symptomatic treatment.

Home Delivery for Filgrastim in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including filgrastim.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for filgrastim and other medicines and health products. Home delivery services for filgrastim may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take filgrastim only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for filgrastim before they complete the sale. You can get this information while placing the order for filgrastim with the pharmacy.

Filgrastim is a generic medicine name and there are several brands available for it. Some of the brands for filgrastim might be better known than filgrastim itself. If the pharmacy that's willing to deliver medicines to your home doesn't have filgrastim in stock, you can ask for one of the branded alternatives for filgrastim.