Clioquinol + Betamethasone valerate Pharmacology

Clioquinol + Betamethasone valerate

About Clioquinol + Betamethasone valerate
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Mechanism of Action of Clioquinol + Betamethasone valerate
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Pharmacokinets of Clioquinol + Betamethasone valerate
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Onset of Action for Clioquinol + Betamethasone valerate
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Duration of Action for Clioquinol + Betamethasone valerate
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Half Life of Clioquinol + Betamethasone valerate
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Side Effects of Clioquinol + Betamethasone valerate
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Contra-indications of Clioquinol + Betamethasone valerate
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Special Precautions while taking Clioquinol + Betamethasone valerate
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Clioquinol + Betamethasone valerate
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Interactions for Clioquinol + Betamethasone valerate
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Typical Dosage for Clioquinol + Betamethasone valerate
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Schedule of Clioquinol + Betamethasone valerate
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Storage Requirements for Clioquinol + Betamethasone valerate
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Effects of Missed Dosage of Clioquinol + Betamethasone valerate
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Effects of Overdose of Clioquinol + Betamethasone valerate
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Clioquinol

About Clioquinol
Hydroxyquinolines derivative, Antifungal drug , Antibacterial and antiprotozoal.
Mechanism of Action of Clioquinol
Clioquinol topical is an antifungal and antibacterial medication. Clioquinol topical prevents fungus from growing on skin.
Pharmacokinets of Clioquinol
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Onset of Action for Clioquinol
N/A
Duration of Action for Clioquinol
N/A
Half Life of Clioquinol
N/A
Side Effects of Clioquinol
1.Blistering
2.Itching
3.Redness
4.Peeling
5.Dryness
6.Swelling
7.Irritation of the skin.
Contra-indications of Clioquinol
1.Hypersensitivity to Clioquinol
Special Precautions while taking Clioquinol
N/A
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Clioquinol
1.Eczema
2.Athlete`s foot
Interactions for Clioquinol
N/A
Typical Dosage for Clioquinol
Clean and dry the affected area. Apply a small amount of the cream two or three times daily as directed for up to 1 week.
Schedule of Clioquinol
N/A
Storage Requirements for Clioquinol
Store in cool, dry and dark place.Keep out of the reach of children.
Effects of Missed Dosage of Clioquinol
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Clioquinol
Give symptomatic and supportive treatment

Betamethasone valerate

About Betamethasone valerate
It is a topical steroid
Mechanism of Action of Betamethasone valerate
The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Betamethasone valerate
Absorption: It is absorbed in to the systemic circulation and the amount is depending on the potency, amount applied and the nature of the skin at the site of application. Absorption increases at the site of skin damage, inflammation or occlusion.

Onset of Action for Betamethasone valerate
N/A
Duration of Action for Betamethasone valerate
N/A
Half Life of Betamethasone valerate
N/A
Side Effects of Betamethasone valerate
1.Thinning of the skin
2.Loss of elasticity
3.Increased hair growth
4.Acne at the site of application
5.Mild depigmentation
6.Rosacea
Contra-indications of Betamethasone valerate
1.Untreated bacterial, virus or fungal infections
2.Acne vulgaris,
3.Peri-oral dermatitis,
4.Scabies,
5.Leg ulcers,
6.Tuberculosis of the skin,
7.Varicose ulcers,
8.Skin lesions caused by infections with ring worm,. fungi (e.g. Candida, Tinea) or bacteria (e.g. impetigo)
9.Hypersensitivity to Betamethasone and other corticosteroids.
10.Discoid lupus Erythematosus
Special Precautions while taking Betamethasone valerate
1.Avoid contact with eyes
2.For external use only
3.Prolonged use
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Betamethasone valerate
1.Psoriasis,
2.Eczema,
3.Otitis externa,
4.Lichen simplex and planus,
5.Anal and vulval Pruritis,
6.Seborrheic dermatitis,
7.Contact dermatitis,
8.Steroidal responsive dermatoses of the scalp
Interactions for Betamethasone valerate
N/A
Typical Dosage for Betamethasone valerate
Topical:
Betamethasone Valerate: Apply to the affected area as thin film 1 - 4 times daily depending upon the severity, skin and rate of absorption.
Dermatoses of the scalp: (Betamethasone Valerate 0.12%): Small amount of foam is applied in to the scalp with gentle massage 2 times a day for up to 2 weeks.
Schedule of Betamethasone valerate
N/A
Storage Requirements for Betamethasone valerate
Store at room temperature in a well closed; light resistant container. Protect from excess heat and moisture. Keep out of reach of children.
Effects of Missed Dosage of Betamethasone valerate
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Betamethasone valerate
Provide symptomatic treatment and supportive measures.

Home Delivery for Clioquinol + Betamethasone valerate in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for clioquinol + betamethasone valerate and other medicines and health products. Home delivery services for clioquinol + betamethasone valerate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take clioquinol + betamethasone valerate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for clioquinol + betamethasone valerate before they complete the sale. You can get this information while placing the order for clioquinol + betamethasone valerate with the pharmacy.

Clioquinol + Betamethasone valerate is a generic medicine name and there are several brands available for it. Some of the brands for clioquinol + betamethasone valerate might be better known than clioquinol + betamethasone valerate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have clioquinol + betamethasone valerate in stock, you can ask for one of the branded alternatives for clioquinol + betamethasone valerate.