Cyclopentolate Pharmacology

Cyclopentolate

About Cyclopentolate
Ophthalmic Anticholinergic(anti-muscarinic), A mydriatic and cycloplegic agent for diagnostic purposes.
Mechanism of Action of Cyclopentolate
Cyclopentolate is a muscarinic receptor blocker. It nonselectively inhibits the muscarinic actions of Acetylcholine. Cyclopentolate blocks the muscarinic receptors in the muscles of the eye which are involved in controlling the pupil size and the shape of the lens. Cyclopentolate blocks the cholinergic nerves supplying the smooth muscles of iris and produces Mydriasis. It also causes paralysis of ciliary muscle and produces a tightening of the suspensory ligament and results in flattening of the lens and a consequent increase in focal length. Because of paralysis of muscle cannot constrict the pupils for viewing near object or prevents the eye from accommodating for near vision (Cycloplegia).
Cyclopentolate is given as eye drops to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly. It is often used to aid eye examinations in young children.
Pharmacokinets of Cyclopentolate
Absorption: Cyclopentolate is readily absorbed after ophthalmic use.
Onset of Action for Cyclopentolate
Rapid
Duration of Action for Cyclopentolate
6 - 24 days
Half Life of Cyclopentolate
N/A
Side Effects of Cyclopentolate
1.Photophobia
2.Irritation
3.Contact dermatitis
4.Blurring
5.Mydriasis
6.Tachycardia
7.Ataxia
8.Pain
9.Lacrimation (hyperemia)
10.Increased intraocular pressure
Contra-indications of Cyclopentolate
1 Hypersensitivity to Cyclopentolate and other belladonna alkaloids
2.Aangle closure glaucoma
Special Precautions while taking Cyclopentolate
1.Avoid the use of medicament if any allergic reactions occur
2.Any work that require good vision like driving vehicle operating machine
3.Wear sun glasses
4.Raised intraocular pressure
5.Avoid use of soft contact lens

Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Cyclopentolate
1 Dilating the pupil to aid examination of the eye
2.Cycloplegic refraction
Interactions for Cyclopentolate
N/A
Typical Dosage for Cyclopentolate
Adult and children
Cyclopentolate 0.5,1 and 2 % eye drops are available.
Eye drop: Instill 1 drop 40 - 50 minutes before procedure and repeat 1 drop in 5 minutes if needed.
Schedule of Cyclopentolate
N/A
Storage Requirements for Cyclopentolate
Store in a cool dry place in a tightly closed container. Protect from heat and light. Keep out of the reach of children. Discard the drug 1 month after opening.
Effects of Missed Dosage of Cyclopentolate
Instill the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Cyclopentolate
A topical ocular overdose of an ophthalmic product containing Cyclopentolate may be flushed from the eye with warm tap water.

Home Delivery for Cyclopentolate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cyclopentolate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cyclopentolate and other medicines and health products. Home delivery services for cyclopentolate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cyclopentolate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cyclopentolate before they complete the sale. You can get this information while placing the order for cyclopentolate with the pharmacy.

Cyclopentolate is a generic medicine name and there are several brands available for it. Some of the brands for cyclopentolate might be better known than cyclopentolate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cyclopentolate in stock, you can ask for one of the branded alternatives for cyclopentolate.