Apraclonidine Pharmacology

Apraclonidine

About Apraclonidine

Adrenergic Alpha2 Agonist, Ophthalmic, Ocular hypotensive ,Anti glucoma.

Mechanism of Action of Apraclonidine

Apraclonidine is a derivative of Clonidine.It is a relatively selective alpha adrenergic agonist.When instilled into the eye, Apraclonidine reduces intraocular pressure by the reduction of aqueous formation.

Pharmacokinets of Apraclonidine

N/A

Onset of Action for Apraclonidine

within 1 hour

Duration of Action for Apraclonidine

N/A

Half Life of Apraclonidine

N/A

Side Effects of Apraclonidine

Surgical Use
1.Upper lid elevation
2.Conjunctival blanching
3.Mydriasis
Glaucoma Therapy:
1.Hyperemia
2.Pruritus
3.Discomfort
4.Foreign body sensation
5.Tearing
6.Oedema of the lids and conjunctiva

Contra-indications of Apraclonidine

1.Hypersensitivity to Apraclonidine
2.Patient on MAOI therapy
3.Severe cardiovascular diseases

Special Precautions while taking Apraclonidine

1.History of angina
2.Severe coronary insufficiency
3.Recent myocardial infarction
4.Heart failure
5.Cerebrovascular diseases
6.Vasovagal attack
7.Chronic renal failure
8.Depresssion
9.Monitor intraoccular pressure and visual fields

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Contraindicated

Indications for Apraclonidine

1.To control intraoccular pressure

Interactions for Apraclonidine

Topical Beta blocker or Pilocarpine: May produce additive lowering of intraocular pressure.

Typical Dosage for Apraclonidine

Apraclonidine 0.5% and 1% ophthalmic solutions are available,
1.Control of post operative elevation of intraocular pressure after anterir segment laser surgery: Apply 1 drop 1 hour before laser surgery and 1 drop immediately after completion of procedure.
2.Short term treatment of chronic glaucoma: 1 drop 3 times daily usually used for maximum of 1 month.

Schedule of Apraclonidine

N/A

Storage Requirements for Apraclonidine

Store between 2 and 30?C. Do not freeze. Protect from light.

Effects of Missed Dosage of Apraclonidine

Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.

Effects of Overdose of Apraclonidine

Give supportive measures and symptomatic treatment.

Home Delivery for Apraclonidine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including apraclonidine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for apraclonidine and other medicines and health products. Home delivery services for apraclonidine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take apraclonidine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for apraclonidine before they complete the sale. You can get this information while placing the order for apraclonidine with the pharmacy.

Apraclonidine is a generic medicine name and there are several brands available for it. Some of the brands for apraclonidine might be better known than apraclonidine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have apraclonidine in stock, you can ask for one of the branded alternatives for apraclonidine.