Ketoconazole (Eye Prep.) Pharmacology

Ketoconazole (Eye Prep.)

About Ketoconazole (Eye Prep.)
Imidazole derivative, A broad spectrum Antifungal.
Mechanism of Action of Ketoconazole (Eye Prep.)
Ketoconazole is fungicidal or fungistatic depending on the drug concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair biosynthesis of ergosterol for the cytoplasmic membrane. This will leads to accumulation of 14 - alpha-methyl sterols and impair the functions of certain membrane bound enzymes such as ATPase and enzymes of electron transport system and also disrupt the close packing of acyl chains of phospholipids. These will produce inhibition of fungal growth
Pharmacokinets of Ketoconazole (Eye Prep.)
Absorption: Absorption after application in to the eye is limited
Onset of Action for Ketoconazole (Eye Prep.)
N/A
Duration of Action for Ketoconazole (Eye Prep.)
N/A
Half Life of Ketoconazole (Eye Prep.)
N/A
Side Effects of Ketoconazole (Eye Prep.)
1.Irritation
2.Burning sensation
Contra-indications of Ketoconazole (Eye Prep.)
1.Hypersensitivity to Ketoconazole and other azoles
Special Precautions while taking Ketoconazole (Eye Prep.)
1.Stop the use of medicaments if allergic reactions occurs
2.Avoid driving vehicle, operating machine since it produce blurred vision
3.Avoid wearing of contact lenses
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Ketoconazole (Eye Prep.)
1. Fungal infections of the eye
Interactions for Ketoconazole (Eye Prep.)
N/A
Typical Dosage for Ketoconazole (Eye Prep.)
0.3% Eye drop is available.
Initial dose: 1 drop should be instilled in to the affected eye every 4 hours for 3 - 4 days followed by 1 drop every 6 hours for 2 - 3 weeks.
Schedule of Ketoconazole (Eye Prep.)
N/A
Storage Requirements for Ketoconazole (Eye Prep.)
Store in a cool, dry place. Protect from direct light and heat. Discard this preparation four weeks after opening. Keep out of reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Ketoconazole (Eye Prep.)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Ketoconazole (Eye Prep.)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes

Home Delivery for Ketoconazole (Eye Prep.) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including ketoconazole (eye prep.).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for ketoconazole (eye prep.) and other medicines and health products. Home delivery services for ketoconazole (eye prep.) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take ketoconazole (eye prep.) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for ketoconazole (eye prep.) before they complete the sale. You can get this information while placing the order for ketoconazole (eye prep.) with the pharmacy.

Ketoconazole (Eye Prep.) is a generic medicine name and there are several brands available for it. Some of the brands for ketoconazole (eye prep.) might be better known than ketoconazole (eye prep.) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have ketoconazole (eye prep.) in stock, you can ask for one of the branded alternatives for ketoconazole (eye prep.).