Tobramycin (Eye Prep.) Pharmacology

Tobramycin (Eye Prep.)

About Tobramycin (Eye Prep.)
Aminoglycoside derivative, Ophthalmic Antibiotic.
Mechanism of Action of Tobramycin (Eye Prep.)
Tobramycin is a water soluble amino glycoside antibiotic active against a variety of ophthalmic bacterial pathogens.Tobramycin exerts its bactericidal action against gram- negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1.Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2.Misleading of m-RNA codon by bacterial ribosome, 3.Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4.Bacterial cell lysis. Some bacterial strains like pseudomonas are more sensitive to Tobramycin than Gentamicin
Pharmacokinets of Tobramycin (Eye Prep.)
Absorption: Absorption after ophthalmic use is minimal.
Onset of Action for Tobramycin (Eye Prep.)
N/A
Duration of Action for Tobramycin (Eye Prep.)
N/A
Half Life of Tobramycin (Eye Prep.)
N/A
Side Effects of Tobramycin (Eye Prep.)
1. Burning
2. Stinging
3. Swelling of the eyelids
4. Blurred vision
5. Rredness
6. Irritation
7. Itching
8. Sensitivity to light may occur
9. Conjunctival Erythema
Contra-indications of Tobramycin (Eye Prep.)
1. Hypersensitivity to Tobramycin
Special Precautions while taking Tobramycin (Eye Prep.)
1. Prolonged use
2. If irritation occurs then discontinue the use of medicaments
3. Avoid contact lenses
4. Wear sun glasses if sensitivity to sunlight occurs
5. Avoid driving vehicle, operating machine since it produces blurred vision
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Contraindicated
NEONATES : Contraindicated
Indications for Tobramycin (Eye Prep.)
Treatment of external infections of the eye and its adnexa caused by susceptible bacteria
Interactions for Tobramycin (Eye Prep.)
N/A
Typical Dosage for Tobramycin (Eye Prep.)
0.3% Tobramycin eye drops or ointment is used.
Eye Drops:
Mild to moderate disease: Instill 1 - 2 drops into the affected eye every 4 hours for 7 to 10 days.
In severe infections: Instill 2drops into the eye every 1 hour until improvement, and then reduce the dose.
Eye Ointment contains 3 mg/g Tobramycin
Mild to moderate disease: apply a 1 - 1.5 cm ribbon into the affected eye 2-3 times per day.
In severe infection, instill a 1 - 1.5 cm ribbon into the affected eye every 3 - 4 hours until improvement, and then reduce the dose.
Schedule of Tobramycin (Eye Prep.)
N/A
Storage Requirements for Tobramycin (Eye Prep.)
Store at cool dry place. Protect from light. Do not freeze. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Tobramycin (Eye Prep.)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Tobramycin (Eye Prep.)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Tobramycin (Eye Prep.) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including tobramycin (eye prep.).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for tobramycin (eye prep.) and other medicines and health products. Home delivery services for tobramycin (eye prep.) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take tobramycin (eye prep.) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for tobramycin (eye prep.) before they complete the sale. You can get this information while placing the order for tobramycin (eye prep.) with the pharmacy.

Tobramycin (Eye Prep.) is a generic medicine name and there are several brands available for it. Some of the brands for tobramycin (eye prep.) might be better known than tobramycin (eye prep.) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tobramycin (eye prep.) in stock, you can ask for one of the branded alternatives for tobramycin (eye prep.).