Norfloxacin (Eye Drops) Pharmacology

Norfloxacin (Eye Drops)

About Norfloxacin (Eye Drops)
N/A
Mechanism of Action of Norfloxacin (Eye Drops)
Norfloxacin is a bacteriostatic at low concentration and bactericidal at high concentration. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Norfloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.
Pharmacokinets of Norfloxacin (Eye Drops)
Absorption: Absorption after ophthalmic application is minimal
Onset of Action for Norfloxacin (Eye Drops)
N/A
Duration of Action for Norfloxacin (Eye Drops)
N/A
Half Life of Norfloxacin (Eye Drops)
N/A
Side Effects of Norfloxacin (Eye Drops)
1. Burning
2. Irritation
3. Itching
4. Bitter taste
5. Blurred vision
6. Increased sensitivity of the eyes to light
7. Redness
8. Swelling
9. Pain
Contra-indications of Norfloxacin (Eye Drops)
1. Hypersensitivity to Norfloxacin and other Fluoroquinolones
2. Not use injection or subconjunctivally in to the eye
Special Precautions while taking Norfloxacin (Eye Drops)
1. Prolonged use
2. If irritation occurs then discontinue the use of medicaments
3. Avoid contact lenses
4. Wear sun glasses if sensitivity to sunlight occurs
5. Avoid driving vehicle since it causes blurred vision
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Contraindicated
NEONATES : Contraindicated
Indications for Norfloxacin (Eye Drops)
1. Conjunctivitis
2. Corneal ulcers
3. Keratitis
4. Blepharitis
5. Dacrocystitis
6. Trachoma
7. Keratoconjunctivitis
8. Acute meibomianitis
9. Prophylaxis of ocular infections
Interactions for Norfloxacin (Eye Drops)
N/A
Typical Dosage for Norfloxacin (Eye Drops)
Norfloxacin 0.3 %w/v drops and ointments are available.
Eye drops: 1-2 drops 6 times daily.
Severe infections: 2 drops should be applied every hour.
Eye ointment: Apply ? inch ribbon 6 - 8 times daily and then reduce the dose depending on infection

Schedule of Norfloxacin (Eye Drops)
N/A
Storage Requirements for Norfloxacin (Eye Drops)
Store at cool dry place. Protect from light. Do not freeze. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Norfloxacin (Eye Drops)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Norfloxacin (Eye Drops)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Norfloxacin (Eye Drops) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including norfloxacin (eye drops).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for norfloxacin (eye drops) and other medicines and health products. Home delivery services for norfloxacin (eye drops) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take norfloxacin (eye drops) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for norfloxacin (eye drops) before they complete the sale. You can get this information while placing the order for norfloxacin (eye drops) with the pharmacy.

Norfloxacin (Eye Drops) is a generic medicine name and there are several brands available for it. Some of the brands for norfloxacin (eye drops) might be better known than norfloxacin (eye drops) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have norfloxacin (eye drops) in stock, you can ask for one of the branded alternatives for norfloxacin (eye drops).