Gentamicin (Eye/Ear Drops) Pharmacology

Gentamicin (Eye/Ear Drops)

About Gentamicin (Eye/Ear Drops)
It is an aminoglycoside antiinfective preparation.
Mechanism of Action of Gentamicin (Eye/Ear Drops)
Gentamicin exerts its bactericidal action against gram- negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1.Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2.Misleading of m-RNA codon by bacterial ribosome, 3.Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4.Bacterial cell lysis. Some bacterial strains resistant to other amino glycosides are sensitive to Gentamicin
Pharmacokinets of Gentamicin (Eye/Ear Drops)
Absorption: Only a very small amount of the drug enter in to the systemic circulation
Onset of Action for Gentamicin (Eye/Ear Drops)
N/A
Duration of Action for Gentamicin (Eye/Ear Drops)
N/A
Half Life of Gentamicin (Eye/Ear Drops)
N/A
Side Effects of Gentamicin (Eye/Ear Drops)
1.Burning
2.Irritation
3.Itching
4.Swelling
5.Redness
6.Pain in or around the eyes or ears
7.Hearing loss
8.Ringing in the ear
9.Dizziness
10.Loss of coordination
11.Stinging
Contra-indications of Gentamicin (Eye/Ear Drops)
1. Hypersensitivity to Gentamicin
Special Precautions while taking Gentamicin (Eye/Ear Drops)
1. Prolonged use
2. If irritation occurs then discontinue the use of medicaments
3. Avoid contact lenses
Pregnancy Related Information
EYE DROPS: EAR DROPS:
Use with caution Contraindicated

Old Age Related Information
EYE DROPS: EAR DROPS:
Use with caution Use with caution
Breast Feeding Related Information
EYE DROPS: EAR DROPS:
Use with caution Contraindicated
Children Related Information
EYE DROPS: EAR DROPS:
Use with caution Use with caution
NEONATES:
EYE DROPS: EAR DROPS:
Contraindicated Contraindicated
Indications for Gentamicin (Eye/Ear Drops)
1.Bacterial Otitis externa
2.External ocular infections
Interactions for Gentamicin (Eye/Ear Drops)
N/A
Typical Dosage for Gentamicin (Eye/Ear Drops)
Gentamicin 0.3% w/v solution is available.
Eyes: 1 or 2 drops should be instilled in the affected eye up to 3 - 4 times a day, or more times if required and then reduce the dose until the infection is controlled
Ears: The area should be cleaned and 2 - 3 drops instilled in the affected ear three to four times a day and at night, or more frequently if required.
Schedule of Gentamicin (Eye/Ear Drops)
N/A
Storage Requirements for Gentamicin (Eye/Ear Drops)
Store at cool dry place. Do not freeze. Keep out of the reach of children
Effects of Missed Dosage of Gentamicin (Eye/Ear Drops)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Gentamicin (Eye/Ear Drops)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Gentamicin (Eye/Ear Drops) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including gentamicin (eye/ear drops).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for gentamicin (eye/ear drops) and other medicines and health products. Home delivery services for gentamicin (eye/ear drops) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take gentamicin (eye/ear drops) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for gentamicin (eye/ear drops) before they complete the sale. You can get this information while placing the order for gentamicin (eye/ear drops) with the pharmacy.

Gentamicin (Eye/Ear Drops) is a generic medicine name and there are several brands available for it. Some of the brands for gentamicin (eye/ear drops) might be better known than gentamicin (eye/ear drops) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have gentamicin (eye/ear drops) in stock, you can ask for one of the branded alternatives for gentamicin (eye/ear drops).