Terlipressin Pharmacology

Terlipressin

About Terlipressin
A long acting synthetic vasopressin analogue, In bleeding esophageal varices.
Mechanism of Action of Terlipressin
Terlipressin is a long acting synthetic analogue of vasopressin, which has been used in the treatment of acute variceal hemorrhage. It also directly constricts blood vessels through V1 (Vasopressin receptor 1)receptors and controls bleeding.
Pharmacokinets of Terlipressin
Absorption: It is completely absorbed after parenteral administration.
Onset of Action for Terlipressin
N/A
Duration of Action for Terlipressin
N/A
Half Life of Terlipressin
N/A
Side Effects of Terlipressin
1.Headache
2.Nausea
3.Vomiting
4.Tremor
5.Vertigo
6.Angina
7.Arrhythmias
8.Cardiac arrest
9.Myocardial ischaemia
10.Pallor
11.Decreased cardiac out put
12.Flatulence
13.Abdominal cramps
14.Cutaneous gangrene
15.Water intoxication
16.Hypersensitivity reactions
17.Urticaria
18.Angioedema
19.Bronchoconstriction
20.Anaphylaxis
21.Hypertension
Contra-indications of Terlipressin
1. Hypersensitivity to the drug
2. Chronic nephritis
3. Coronary artery disease
4. Hypertension
5. Psychogenic polydypsia
Special Precautions while taking Terlipressin
Seizure
2. Migraine
3. Asthma
4. Cardiovascular disease
5. Renal impairment
6. Heart failure
7. Goiter
8. Fluid overload
Pregnancy Related Information
Contraindicated
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Terlipressin
Oesophageal variceal bleeding
Interactions for Terlipressin
N/A
Typical Dosage for Terlipressin
IV
Adult: 2mg every 4 - 6 hours until bleeding is controlled for up to 3days
Schedule of Terlipressin
H
Storage Requirements for Terlipressin
Store the injections at 2 to 8 degree C. Keep out of reach of children
Effects of Missed Dosage of Terlipressin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose
Effects of Overdose of Terlipressin
Give supportive measures and symptomatic treatment.

Home Delivery for Terlipressin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including terlipressin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for terlipressin and other medicines and health products. Home delivery services for terlipressin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take terlipressin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for terlipressin before they complete the sale. You can get this information while placing the order for terlipressin with the pharmacy.

Terlipressin is a generic medicine name and there are several brands available for it. Some of the brands for terlipressin might be better known than terlipressin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have terlipressin in stock, you can ask for one of the branded alternatives for terlipressin.