Cetrorelix acetate Pharmacology

Cetrorelix acetate

About Cetrorelix acetate
GnRH antagonist, A systemic female anti infertility agent.
Mechanism of Action of Cetrorelix acetate
GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner. Cetrorelix blocks the effects of the naturally occurring gonadotropin-releasing hormone (GnRH). GnRH controls the release of another hormone, luteinizing hormone (LH), which induces ovulation (release of an egg from the ovary) during the menstrual cycle. During hormone treatment for ovarian stimulation, premature ovulation may lead to eggs that are not suitable for fertilization. Cetrorelix blocks this undesirable premature ovulation.
Pharmacokinets of Cetrorelix acetate
Absorption:It is rapidly absorbed after subcutaneous administration.Distribution:It is distributed mainly in protein bound form. Metabolism:It undergoes hepatic metabolism.Excretion:Drug and its metabolites are excreted mainly in urine and bile.
Onset of Action for Cetrorelix acetate
N/A
Duration of Action for Cetrorelix acetate
N/A
Half Life of Cetrorelix acetate
N/A
Side Effects of Cetrorelix acetate
1.Nausea
2.Headache
3.Redness
4.Bruising
5.Itching
6.Swelling at the injection site.
Contra-indications of Cetrorelix acetate
1. Hypersensitivity to Cetrorelix acetate
2. Known hypersensitivity to GnRH or any other GnRH analogs.
3. Severe renal impairment
4. Allergic reaction to mannitol
5. Severe liver function
6. Post-menopausal women

Special Precautions while taking Cetrorelix acetate
1.Renal impairment
2.Hepatic impairment
Pregnancy Related Information
Contraindicated
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated
Children Related Information
N/A
Indications for Cetrorelix acetate
1.Treatment of female infertility
Interactions for Cetrorelix acetate
N/A
Typical Dosage for Cetrorelix acetate
Adult:
Subcuaneous injection in to the lower abdominal wall.
Ovarian stimulation therapy with gonadotropins is started on cycle Day 2 or 3. The dose of gonadotropins should be adjusted according to individual response.The drug to be taken either once daily (0.25 mg dose) or once (3 mg dose) during the early- to mid-follicular phase.
Schedule of Cetrorelix acetate
N/A
Storage Requirements for Cetrorelix acetate
Store at controlled room temperature.Protect from heat,light and moisture.Keep out of the reach of children.
Effects of Missed Dosage of Cetrorelix acetate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.
Effects of Overdose of Cetrorelix acetate
Give supportie measures and symptomatic treatment.

Home Delivery for Cetrorelix acetate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cetrorelix acetate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cetrorelix acetate and other medicines and health products. Home delivery services for cetrorelix acetate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cetrorelix acetate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cetrorelix acetate before they complete the sale. You can get this information while placing the order for cetrorelix acetate with the pharmacy.

Cetrorelix acetate is a generic medicine name and there are several brands available for it. Some of the brands for cetrorelix acetate might be better known than cetrorelix acetate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cetrorelix acetate in stock, you can ask for one of the branded alternatives for cetrorelix acetate.