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- Pharmacology For L-Ornithine L-Aspartate + Nicotinamide + Riboflavin
L-Ornithine L-Aspartate + Nicotinamide + Riboflavin Pharmacology
L-Ornithine L-Aspartate + Nicotinamide + Riboflavin
About L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AMechanism of Action of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/APharmacokinets of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AOnset of Action for L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/ADuration of Action for L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AHalf Life of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/ASide Effects of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AContra-indications of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/ASpecial Precautions while taking L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AInteractions for L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/ATypical Dosage for L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/ASchedule of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AStorage Requirements for L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AEffects of Missed Dosage of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AEffects of Overdose of L-Ornithine L-Aspartate + Nicotinamide + RiboflavinN/AL-Ornithine L-Aspartate
About L-Ornithine L-AspartateA dietary supplement, a Hepatobiliary preparation., In Hepatic dysfunction.Mechanism of Action of L-Ornithine L-AspartateL-Ornithine L-Aspartate is a stable salt of Ornithine and aspartic acid. Ornithine and Aspartate are the substrate in the metabolic conversion of ammonia to urea and glutamate respectively. LOLA increases ammonia detoxification and decreases ammonia level in the blood and useful in patient with hepatic encephalopathy. It is also involved in the Krebs cycle and it is helpful in energy production.Pharmacokinets of L-Ornithine L-AspartateN/AOnset of Action for L-Ornithine L-AspartateN/ADuration of Action for L-Ornithine L-AspartateN/AHalf Life of L-Ornithine L-AspartateN/ASide Effects of L-Ornithine L-Aspartate1.Transient nausea
2.Vomiting
Contra-indications of L-Ornithine L-AspartatePatient with creatinine level more than 3 mg / 100 mlSpecial Precautions while taking L-Ornithine L-AspartateN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for L-Ornithine L-Aspartate1.Acute and chronic hepatitis
2.Cirrhosis of liver
3.Alcoholic liver damage
4.Adjunct to hepatotoxic drugs
5.Hepatocellular insufficiency- stimulus for glutamine synthesis
Interactions for L-Ornithine L-AspartateN/ATypical Dosage for L-Ornithine L-AspartateORAL
Adult: 1 - 2tablets 3 times daily each tablet contain 150 mg of L-Ornithine L-aspartate
Schedule of L-Ornithine L-AspartateN/AStorage Requirements for L-Ornithine L-AspartateStore at room temperatureEffects of Missed Dosage of L-Ornithine L-AspartateTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of L-Ornithine L-AspartateGive supportive measures and symptomatic treatment.Nicotinamide
About NicotinamideWater Soluble Vitamin(B complex- vitamin B3), Amide of nicotinic acid.Mechanism of Action of NicotinamideNicotinamide exerts its action by influencing metabolic reactions. It is converted in to coenzymes Ncotinamide adenine dinucleotide (NAD) and its phosphate Ncotinamide adenine dinucleotide phosphate (NADP) involved in oxidation reduction reactions. These pyridine nucleotides act as hydrogen acceptors in the electron transport chain in tissue respiration, glycolysis, and fat synthesis. Nicotinic acid in high doses has vasodilator effects and also improves lipid profile; reduces serum cholesterol, raises HDL level, lowers VLDL, and LDL levels.Pharmacokinets of NicotinamideAbsorption: Well absorbed orally, Distribution: Widely distributed in the body, and also secreted in to breast milk, Modest amounts are stored in liver, Metabolism: Metabolized in to active metabolites in liver, Excretion: Extra drug is excreted through urine.Onset of Action for NicotinamideN/ADuration of Action for NicotinamideN/AHalf Life of NicotinamideN/ASide Effects of Nicotinamide1.Activation of peptic ulcer
2.Nausea
3.Vomiting
4.Diarrhoea
5.Headache
6.Hypotension
7.Arrhythmias
8.Hepatic impairment
Contra-indications of Nicotinamide1.Hypersensitivity to the drug
2.Hepatic impairment
3.Peptic ulcer
4.Severe hypotension
5.Arterial haemorrhage
Special Precautions while taking Nicotinamide1.History of liver disease
2.Gall bladder diseases
3.Gout
4.Coronary artery diseases
5.Diabetes mellitus
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Nicotinamide1.Pellagra
2.Niacin deficiency
3.Hartnup disease
Interactions for NicotinamideN/ATypical Dosage for NicotinamidePellagra: 200 to 500mg daily in divided doses.
Prophylactically: 20 to 50mg daily.
Dietary supplement: 10 to 20mg daily
Hartnup disease: 50 to 200mg daily in divided doses.
Schedule of NicotinamideN/AStorage Requirements for NicotinamideStore at controlled room temperature at a range of 15 to 30 degree C.Effects of Missed Dosage of NicotinamideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of NicotinamideProvide supportive measures and symptomatic treatment.About N/AMechanism of Action of N/APharmacokinets of N/AOnset of Action for N/ADuration of Action for N/AHalf Life of N/ASide Effects of N/AContra-indications of N/ASpecial Precautions while taking N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for N/AInteractions for N/ATypical Dosage for N/ASchedule of N/AStorage Requirements for N/AEffects of Missed Dosage of N/AEffects of Overdose of N/AHome Delivery for L-Ornithine L-Aspartate + Nicotinamide + Riboflavin in Your City
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