Bisacodyl Pharmacology

Bisacodyl

About Bisacodyl
Diphenyl methane derivative ,Stimulant (irritant)Laxative
Mechanism of Action of Bisacodyl
Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation.
Pharmacokinets of Bisacodyl
Absorption: 5% of the drug is absorbed after oral administration.Distribution: It is distributed locally. Metabolism: It is hydrolyzed by intestinal enzymes esterases and bacteria in the bowel to active desacetyl forms.Excretion: Bisacodyl is excreted mainly in the stool. Absorbed drug is excreted in urine.

Onset of Action for Bisacodyl
Tablets: 6 - 12 hours
Suppositories: 15 - 60 minutes
Enema: 5 - 20 minutes
Tablets: 6 - 12 hours
Suppositories: 15 - 60 minutes
Enema: 5 - 20 minutes
Tablets: 6 - 12 hours
Suppositories: 15 - 60 minutes
Enema: 5 - 20 minutes
6 - 12 hours
Duration of Action for Bisacodyl
N/A
Half Life of Bisacodyl
N/A
Side Effects of Bisacodyl
1.Abdominal discomfort
2.Abdominal cramps
3.Diarrhea
4.Rectal irritation
Contra-indications of Bisacodyl
1.Hypersensitivity to Bisacodyl
2.Intestinal obstruction
3.Obstruction of the intestines due to loss of intestinal movement
4.Severe dehydration
5.Sudden abdominal conditions requiring surgery (appendicitis)
6.Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease)
7.Anal fissure
8.Ulcerative proctitis
Special Precautions while taking Bisacodyl
1.Nausea
2.Vomiting
3.Abdominal pain
4.Prolong use
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution.
Enema is contraindicated in children below 12 years
NEONATES: contraindicated
Indications for Bisacodyl
1.Bowel evacuation in prior to radiological examinations
2.Constipation
3.Laxative in postoperative, ante partum, or postpartum care
Interactions for Bisacodyl
N/A
Typical Dosage for Bisacodyl
Oral
Adult: 5 - 15 mg / day if needed dose can be increased to 30 mg as a single dose.
Children: 5 - 10 mg / day
Suppositories: Adult: 1 suppository (10 mg / day) /day
Children: ? - 1 suppository (5 - 10mg / day) /day
Enema: Adult: use 30 ml of solution rectally.
Schedule of Bisacodyl
N/A
Storage Requirements for Bisacodyl
Store at room temperature. Keep out of the reach of children
Effects of Missed Dosage of Bisacodyl
Do not apply
Effects of Overdose of Bisacodyl
Give supportive measures and symptomatic treatment.

Home Delivery for Bisacodyl in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including bisacodyl.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for bisacodyl and other medicines and health products. Home delivery services for bisacodyl may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take bisacodyl only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for bisacodyl before they complete the sale. You can get this information while placing the order for bisacodyl with the pharmacy.

Bisacodyl is a generic medicine name and there are several brands available for it. Some of the brands for bisacodyl might be better known than bisacodyl itself. If the pharmacy that's willing to deliver medicines to your home doesn't have bisacodyl in stock, you can ask for one of the branded alternatives for bisacodyl.