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- Pharmacology For Magnesium Hydroxide + Paraffin + Phenolphthalein
Magnesium Hydroxide + Paraffin + Phenolphthalein Pharmacology
Magnesium Hydroxide + Paraffin + Phenolphthalein
About Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AMechanism of Action of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/APharmacokinets of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AOnset of Action for Magnesium Hydroxide + Paraffin + PhenolphthaleinN/ADuration of Action for Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AHalf Life of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/ASide Effects of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AContra-indications of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/ASpecial Precautions while taking Magnesium Hydroxide + Paraffin + PhenolphthaleinN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AInteractions for Magnesium Hydroxide + Paraffin + PhenolphthaleinN/ATypical Dosage for Magnesium Hydroxide + Paraffin + PhenolphthaleinN/ASchedule of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AStorage Requirements for Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AEffects of Missed Dosage of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AEffects of Overdose of Magnesium Hydroxide + Paraffin + PhenolphthaleinN/AMagnesium Hydroxide
About Magnesium HydroxideMineral, Magnesium compound, Antacid and laxative.Mechanism of Action of Magnesium HydroxideIt neutralize the gastric acid (where the hydroxide ions from the Mg(OH)2 combine with acidic H+ ions produced in the form of hydrochloric acid by parietal cells in the stomach). This relieves the hyperacidity problems in the stomach.Pharmacokinets of Magnesium HydroxideN/AOnset of Action for Magnesium HydroxideN/ADuration of Action for Magnesium HydroxideN/AHalf Life of Magnesium HydroxideN/ASide Effects of Magnesium Hydroxide1. Stomach cramps
2. Upset stomach
3. Vomiting
4. Diarrhea
5. Black/tarry stools
6. Rectal bleeding.
7. Constipation
8. Loss of appetite
9. Unusual tiredness
10. Muscle weakness
11. Hypermagnesaemia
12. Renal failure
Contra-indications of Magnesium Hydroxide1. Hypersensitivity to the drug
2. Kidney disease
3. Stomach/abdominal pain
4. Nausea
5. Vomiting
Special Precautions while taking Magnesium Hydroxide1. Colostomy
2. Dehydration
3. Diarrhea
4. Intestinal problems like colitis
5.Do not take any other medication within 1 to 2 hours of taking this medication.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationLess than 6 Years : ContraindicatedIndications for Magnesium Hydroxide1. Constipation
2. Peptic ulcer
3. Hiatal herniaInteractions for Magnesium HydroxideN/ATypical Dosage for Magnesium HydroxideOral-
Adult-
Antacid:
Tab-500mg to 1.5g daily.
Liquid-5-15ml daily.
Laxative:
Tab-2.4-4.8g daily.
Liquid -30-60ml daily.
Schedule of Magnesium HydroxideN/AStorage Requirements for Magnesium HydroxideStore it at room temperature (15-30 degree C) and away from excess heat and moisture.Effects of Missed Dosage of Magnesium HydroxideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Magnesium HydroxideGive symptomatic and supportive treatment.Paraffin
About ParaffinPetroleum based lubricant, A lubricative laxative(faecal softner).Mechanism of Action of ParaffinParaffin liquid is a lubricant laxative. It acts by softening and lubricating the faeces. Liquid Paraffin lubricates the intestinal tract, soften the fecal contents and retard the absorption of water and facilitate the passage of feces. By doing this it relieves constipation and reduces the pain of some conditions such as piles (haemorrhoids).Pharmacokinets of ParaffinAbsorption: After oral administration it is minimally absorbed.Distribution: it is distributed mainly in the colon.Excretion: excreted mainly in the feces.
Onset of Action for Paraffin6 - 8 hours(oral)
2 - 15 minutes(rectal)Duration of Action for ParaffinvariableHalf Life of ParaffinN/ASide Effects of Paraffin1.Abdominal pain
2.Irritation of the back passage
3.Nausea
4.Vomiting
5.Diarrhoea
6.Decreased absorption of nutrients and fat soluble vitamins
7.Lipid pneumonia
8.Anal pruritis
9.Laxative dependence
Contra-indications of Paraffin1.Hypersensitivity to Paraffin liquid
2.Abdominal pain
3.Nausea
4.Vomiting
5.Appendicitis
6.Acute surgical abdomen
7.Intestinal obstruction
8.Colostomy
9.Ileostomy
9.Ulcerative colitis
Special Precautions while taking Paraffin1. Avoid prolonged use
2. Debilitated patients
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: contraindicatedIndications for ParaffinConstipationInteractions for ParaffinN/ATypical Dosage for ParaffinOral:
Adults: 15 - 45 ml as single or divided doses.Take the drug at bed time
Enema: 120ml
CHILDREN:
Above 12 years: same as adult dose
6 - 11 years: 5 - 15 ml as single or divided doses.Take the drug at bed time
Enema: 30 - 60ml
Schedule of ParaffinN/AStorage Requirements for ParaffinStore at room temperature. Protect from heat and light. Keep out of the reach of children.Effects of Missed Dosage of ParaffinN/AEffects of Overdose of ParaffinGive supportive measures and symptomatic treatmentPhenolphthalein
About PhenolphthaleinTriarylmethane dye, Contact(stimulant) laxative.Mechanism of Action of PhenolphthaleinPhenolphthalein is a stimulant laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation.
Nitric oxide (NO) is produced in the intestine, where it stimulates electrolyte secretion and relaxes smooth muscle
Pharmacokinets of PhenolphthaleinN/AOnset of Action for PhenolphthaleinN/ADuration of Action for PhenolphthaleinN/AHalf Life of PhenolphthaleinN/ASide Effects of PhenolphthaleinN/AContra-indications of PhenolphthaleinN/ASpecial Precautions while taking Phenolphthalein1. Symptoms of appendicitis
2. Stomach or bowel conditions that need surgery
3. Hypersensitive to PhenolphthaleinPregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Phenolphthalein1. It is given to treat long-term constipation and to prevent straining.
2. It is given to patients recovering from surgery and those with heart disease or high blood pressureInteractions for PhenolphthaleinN/ATypical Dosage for PhenolphthaleinN/ASchedule of PhenolphthaleinN/AStorage Requirements for PhenolphthaleinN/AEffects of Missed Dosage of PhenolphthaleinN/AEffects of Overdose of PhenolphthaleinN/AHome Delivery for Magnesium Hydroxide + Paraffin + Phenolphthalein in Your City
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