Tripotassium Dicitrato Bismuthate Pharmacology

Tripotassium Dicitrato Bismuthate

About Tripotassium Dicitrato Bismuthate
An ulcer protective agent, chelates and complexes, Antiulcer ,antisecretary drug.
Mechanism of Action of Tripotassium Dicitrato Bismuthate
Tripotassium dicitrato bismuthate is an ulcer protective agent. In the acidic medium at pH <5 it stimulates the Prostaglandin PGE2 production and leads to the stimulation of mucus and bicarbonate secretion. Along with mucus, Tripotassium dicitrato bismuthate forms a glycoprotein bismuth complex which coats the ulcer and retards the migration of H+. This complex acts as a diffusion barrier for Hydrochloric acid. It also kills the H. pylori.
Pharmacokinets of Tripotassium Dicitrato Bismuthate
Absorption: Tripotassium dicitrato bismuthate is poorly absorbed (< 1%) after oral administration.
Excretion: It is excreted mainly in the urine.
Onset of Action for Tripotassium Dicitrato Bismuthate
10 - 30 minutes
Duration of Action for Tripotassium Dicitrato Bismuthate
12- 16 hours
Half Life of Tripotassium Dicitrato Bismuthate
N/A
Side Effects of Tripotassium Dicitrato Bismuthate
1. Darkening of stools
2. Nausea
3. Vomiting
4. Diarrhoea
5. Constipation
6. Dizziness
Contra-indications of Tripotassium Dicitrato Bismuthate
1. Renal failure
2. Hepatic failure
Special Precautions while taking Tripotassium Dicitrato Bismuthate
1. Prolonged use
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Contraindicated
NEONATES: Contraindicated
Indications for Tripotassium Dicitrato Bismuthate
1. Duodenal ulcer
2. Gastric ulcer
3. H. pylori infection
Interactions for Tripotassium Dicitrato Bismuthate
N/A
Typical Dosage for Tripotassium Dicitrato Bismuthate
Oral :
Adult: 120 mg in 2 - 4 times daily to be taken before meals for 4 - 8 weeks.
Children: Not recommended
Schedule of Tripotassium Dicitrato Bismuthate
H
Storage Requirements for Tripotassium Dicitrato Bismuthate
Store at room temperature. Protect from heat and moisture.
Keep out of the reach of children.
Effects of Missed Dosage of Tripotassium Dicitrato Bismuthate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Tripotassium Dicitrato Bismuthate
Give supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage. To reduce the absorption of the drug activated charcoal is given to the patient.

Home Delivery for Tripotassium Dicitrato Bismuthate in Your City

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Please be aware that you should take tripotassium dicitrato bismuthate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for tripotassium dicitrato bismuthate before they complete the sale. You can get this information while placing the order for tripotassium dicitrato bismuthate with the pharmacy.

Tripotassium Dicitrato Bismuthate is a generic medicine name and there are several brands available for it. Some of the brands for tripotassium dicitrato bismuthate might be better known than tripotassium dicitrato bismuthate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tripotassium dicitrato bismuthate in stock, you can ask for one of the branded alternatives for tripotassium dicitrato bismuthate.