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- Pharmacology For Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic Acid
Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic Acid Pharmacology
Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic Acid
About Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AMechanism of Action of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/APharmacokinets of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AOnset of Action for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/ADuration of Action for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AHalf Life of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/ASide Effects of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AContra-indications of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/ASpecial Precautions while taking Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidAlginic acid is used for reflux oesophagitis.
Indications
1.Reflux oesophagitis
2.Heart-burn
3.Regurgitation
Interactions for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/ATypical Dosage for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic Acid2-4 tablets to be chewed after meals and at bed timeSchedule of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AStorage Requirements for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AEffects of Missed Dosage of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AEffects of Overdose of Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic AcidN/AAluminium Hydroxide
About Aluminium HydroxideAntacid,Antidote,Protectant( Topical), In hyperacidity; hyperphosphatemia.Mechanism of Action of Aluminium HydroxideIt neutralizes and reduces stomach acid relieving heartburn (acid reflux, GERD) and indigestion. This results increased pH and reduce the pepsin activity. It also binds to the phosphate in the gut and form a nonsoluble nonabsorbable aluminium phosphate complex.Pharmacokinets of Aluminium HydroxideAbsorption- Poorly absorbed.Excretion- Excreted through feces and breast milkOnset of Action for Aluminium HydroxideN/ADuration of Action for Aluminium Hydroxide20 to 180minutesHalf Life of Aluminium HydroxideN/ASide Effects of Aluminium Hydroxide1. Loss of appetite
2. Constipation
3. Hypophosphatemia
4. Osteomalacia
5. Confusion
6. Unusual tiredness or discomfort
7. Muscle weakness
8. Encephalopathy
Contra-indications of Aluminium Hydroxide1. Hypersensitivity to the drug
2. Renal failure
3. Hypertension
4. Heart disease
5. Kidney disease
6. Gastrointestinal bleeding.
Special Precautions while taking Aluminium Hydroxide1. Stomach problems
2. Allergies
Pregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Aluminium Hydroxide1. Gastric hyperacidity
2. Ulcers
3. Digestive disorders
4. Hyperphosphatemia
5. Oesophagitis
6. Hiatal hernia
7. Gastritis
Interactions for Aluminium HydroxideN/ATypical Dosage for Aluminium HydroxideOral-
Acidity and Hyperphosphatemia -
Adult-
500-1500mg tablet or capsule 1 hr after meals and at bed time
5 to 30 ml suspension1 hr after meals and at bed time as needed
Schedule of Aluminium HydroxideN/AStorage Requirements for Aluminium HydroxideStore it at room temperature and away from excess heat and moisture. Refrigerate the suspension. Do not freeze.Effects of Missed Dosage of Aluminium HydroxideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Aluminium HydroxideGive symptomatic and supportive treatmentMagnesium Trisilicate
About Magnesium TrisilicateMineral, Magnesium compound, Antacid.Mechanism of Action of Magnesium TrisilicateN/APharmacokinets of Magnesium TrisilicateN/AOnset of Action for Magnesium TrisilicateN/ADuration of Action for Magnesium TrisilicateN/AHalf Life of Magnesium TrisilicateN/ASide Effects of Magnesium TrisilicateN/AContra-indications of Magnesium TrisilicateN/ASpecial Precautions while taking Magnesium TrisilicateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Magnesium TrisilicateN/AInteractions for Magnesium TrisilicateN/ATypical Dosage for Magnesium TrisilicateN/ASchedule of Magnesium TrisilicateN/AStorage Requirements for Magnesium TrisilicateN/AEffects of Missed Dosage of Magnesium TrisilicateN/AEffects of Overdose of Magnesium TrisilicateN/ASodium Bicarbonate
About Sodium BicarbonateSodium compound, Systemic Antacid ,alkalinizer.Mechanism of Action of Sodium BicarbonateSodium bicarbonate in water dissociates to sodium (Na+) and bicarbonate (HCO3 -) ions. Sodium (Na+) is the principal cation of the extracellular fluid and it maintains fluid and electrolyte disturbances. Bicarbonate (HC03 -) is a normal constituent of body fluids. Plasma concentration is regulated by the kidney through acidification of the urine when there is a deficit or by alkalinization of the urine when there is an excess. Bicarbonate anion is considered ``labile`` since at a proper concentration of hydrogen ion (H+) it may be converted to carbonic acid (H2CO3) and hence to its volatile form, carbon dioxide (CO2) which is excreted by the lung.
Sodium bicarbonate can neutralize or reduce acids in the blood, or urine. It is also used in emergency medical situations (heart attacks, serious kidney or lung problems) to correct the normal acid-base balance in the blood or as an aid in treating overdoses with certain types of medications.Intravenous sodium bicarbonate therapy increases plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and reverses the clinical manifestations of acidosis.
Sodium bicarbonate is used in a serious condition called metabolic acidosis. This is when the acidity of blood and tissues is abnormally high. It arises when the body`s normal acid balancing mechanisms fail, for example, in cardiac arrest or severe kidney disease. Sodium bicarbonate neutralises the excess acid.
Pharmacokinets of Sodium BicarbonateAbsorption: Sodium bicarbonate is well absorbed and reabsorbed after parenteral administration in ionized forms.
Excretion: Less than 1% is excreted in urine.Onset of Action for Sodium BicarbonateN/ADuration of Action for Sodium BicarbonateN/AHalf Life of Sodium BicarbonateN/ASide Effects of Sodium Bicarbonate1. Gastric disturbances
2. Belching
3. Flatulence
4. Hypernatraemia
5. Alkalosis
6. Pain at the site of injection
7. Venous irritation
8. Chemical cellulites
9. Ulceration
10. Tissue necrosis at the site of infiltration confusion
11. Swelling of the feet and legs
Contra-indications of Sodium Bicarbonate1. Metabolic alkalosis
2. Respiratory alkalosis
3. Patients losing chlorides by vomiting or from continuous suction
4. Patient on diuretics which produces hypochloremic alkalosis
5. Hypocalcaemia in which alkalosis may produce tetany
6. Hypertension
7. Seizure
8. Heart failure
6. Hypernatreamia
Special Precautions while taking Sodium Bicarbonate1. Renal impairment
2. Edema with sodium retention
3. Oliguria
4. Cushing`s syndrome
5. Dehydration
6. Heart problems
7. Hyperventilation
8. Low blood levels of calcium or potassium
9. Ulcers in the esophagus
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Sodium Bicarbonate1. Metabolic acidosis
2. Severe diarrhoea
3. Urine alkalinization
Interactions for Sodium BicarbonateThe renal clearance of the following agents may be :
a) increased - Chlorpropamide, lithium, methotrexate, salicylate, tetracycline.
b) decreased - Anorexients, quinidine, sympathomimetics.
Incompatibility : Avoid adding sodium bicarbonate to parenteral solution containing calcium, precipitation may result. Norepinephrine and dobutamine are incompatible.Typical Dosage for Sodium BicarbonateAdult:
Parenteral
In cardiac arrest: 200 - 300 mEq of a 7.5 - 8.4 % solution as rapidly as possible and in emergency inject 300 - 500 ml of 5% solution.
Metabolic acidosis: 90 - 180 mEq/L as IV during first hour and then adjust the dose depending on patients response.
Urinary alkalization: 0.325 - 2 g in 3- 4 times daily for patients above 60 years maximum dose is 8g and in patients below 60 years is 17 g.
Children: 1 - 10 mEq/kg / day
Children up to two years of age: 1 mEq / kg IV bolus of 4.2% solution and dose may be repeated every 10 minutes. Maximum daily dose: 8 mEq/ kgSchedule of Sodium BicarbonateN/AStorage Requirements for Sodium BicarbonateStore at room temperature between 15 and 30 degrees C Do not freeze. Keep out of the reach of childrenEffects of Missed Dosage of Sodium BicarbonateDo not applyEffects of Overdose of Sodium BicarbonateGive supportive measures and symptomatic treatment. Correct the electrolyte balance. Ammonium chloride can be given in severe alkalosis.Alginic Acid
About Alginic AcidNaturally occurring hydrophilic colloidal polysaccharide, Protective agent against GERDs.Mechanism of Action of Alginic AcidThis naturally occurring hydrophilic colloidal polysaccharide obtained from Sargassum Seaweeds reacts with saliva and produces a foamy froth that layers on the liquid in the stomach. Alginic acid powder swells when wetted with water. This may prevent reflux of acid into the esophagus by keeping the gastric contents in place and reduce the likelihood of reflux irritating the lining of the esophagus. The sodium calcium alginate fibres in haemostatic wound dressings absorbed by body fluids, as the calcium in the fiber is exchanged for sodium from the body fluids mixed salts of sodium and calcium alginate, and processed into non-woven fabric that is used in wound dressings. It binds with heavy metals and radioactive substances to its own molecules. It cannot be broken down by bile or saliva to be absorbed and secreted from the body together with heavy metals and radioactive substances.Pharmacokinets of Alginic AcidWhen ingested, almost all of the alginic acid remains undigested and is excreted either unchanged or as an alginate.Onset of Action for Alginic AcidN/ADuration of Action for Alginic Acid30 to 60 minutesHalf Life of Alginic AcidN/ASide Effects of Alginic Acid1. Abdominal distension
2. Flatulence
3. Chalky taste in your mouth
4. Constipation
5. Diarrhea
6. Nausea
7. Vomiting.
Contra-indications of Alginic Acid1. Hypersensitivity to the drug
2. Heart failure.
3. Renal failure.
Special Precautions while taking Alginic Acid1.Allergies to medicines, foods, or other substances
2.Alzheimer disease
3.Appendicitis
4.Diarrhoea
5.Stomach blockage
6.Kidney problems
7.Liver problems
8.Ileostomy
9.Congestive heart failure
10.Decreased urination
11.Fluid retention
12.Rectal bleeding of unknown cause
13.Recently had stomach bleeding
14.Patient on low salt dietPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Alginic Acid1. Heartburn (including heartburn of pregnancy)
2. Dyspepsia
3. Reflux oesophagitis
4. Hiatus hernia.
5. Protect inflamed areas near the entrance to the stomach (Sodium alginate)
Interactions for Alginic AcidN/ATypical Dosage for Alginic AcidTake the drug as directed by the physician.Schedule of Alginic AcidN/AStorage Requirements for Alginic AcidStore below 25?C in a tightly closed container.Effects of Missed Dosage of Alginic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Alginic AcidGive symptomatic and supportive treatment.Home Delivery for Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic Acid in Your City
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Aluminium Hydroxide + Magnesium Trisilicate + Sodium Bicarbonate + Alginic Acid is a generic medicine name and there are several brands available for it. Some of the brands for aluminium hydroxide + magnesium trisilicate + sodium bicarbonate + alginic acid might be better known than aluminium hydroxide + magnesium trisilicate + sodium bicarbonate + alginic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have aluminium hydroxide + magnesium trisilicate + sodium bicarbonate + alginic acid in stock, you can ask for one of the branded alternatives for aluminium hydroxide + magnesium trisilicate + sodium bicarbonate + alginic acid.