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- Pharmacology For Magaldrate + Methyl Polysiloxane + Oxethazaine
Magaldrate + Methyl Polysiloxane + Oxethazaine Pharmacology
Magaldrate + Methyl Polysiloxane + Oxethazaine
About Magaldrate + Methyl Polysiloxane + OxethazaineN/AMechanism of Action of Magaldrate + Methyl Polysiloxane + OxethazaineN/APharmacokinets of Magaldrate + Methyl Polysiloxane + OxethazaineN/AOnset of Action for Magaldrate + Methyl Polysiloxane + OxethazaineN/ADuration of Action for Magaldrate + Methyl Polysiloxane + OxethazaineN/AHalf Life of Magaldrate + Methyl Polysiloxane + OxethazaineN/ASide Effects of Magaldrate + Methyl Polysiloxane + OxethazaineN/AContra-indications of Magaldrate + Methyl Polysiloxane + OxethazaineN/ASpecial Precautions while taking Magaldrate + Methyl Polysiloxane + OxethazaineN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Magaldrate + Methyl Polysiloxane + OxethazaineN/AInteractions for Magaldrate + Methyl Polysiloxane + OxethazaineN/ATypical Dosage for Magaldrate + Methyl Polysiloxane + OxethazaineN/ASchedule of Magaldrate + Methyl Polysiloxane + OxethazaineN/AStorage Requirements for Magaldrate + Methyl Polysiloxane + OxethazaineN/AEffects of Missed Dosage of Magaldrate + Methyl Polysiloxane + OxethazaineN/AEffects of Overdose of Magaldrate + Methyl Polysiloxane + OxethazaineN/AMagaldrate
About MagaldrateChemical complex of aluminum and magnesium hydroxides, Antacid.Mechanism of Action of MagaldrateThis neutralizes the gastric acid and increases the gastric pH. This reduces the direct acid irritant effect. It also enhances mucosal barrier integrity and improves gastroesophageal sphincter tone.Pharmacokinets of MagaldrateAbsorption- Moderately absorbed after oral administration. Distribution- It is distributed through locally. Excretion- Excreted through feces and a small amount through breast milk.Onset of Action for Magaldrate20minutesDuration of Action for Magaldrate20 to 180 minutesHalf Life of MagaldrateN/ASide Effects of Magaldrate1. Constipation
2. Diarrhea
3. Increased urine pH
4. Decreased serum potassium levels
5. Increased serum calcium levels
Contra-indications of Magaldrate1. Hypersensitivity to the drug or any ingredients of it
2. Renal impairment or diseases
3. Hypophosphatemia
Special Precautions while taking Magaldrate1.Take this medicine between meals and at bedtime.
2.Shake the oral liquid well before each use.
3.Chew the chewable tablet before swallowing.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Magaldrate1. Peptic ulcer
2. Gastritis
3. Reflux oesophagitis
4. Gastric hyperacidity
Interactions for MagaldrateN/ATypical Dosage for MagaldrateOral-
Adults-
Suspension: 5 to 10 ml between meals and at bedtime with water
Schedule of MagaldrateN/AStorage Requirements for MagaldrateStore at room temperature (15 - 25 degree C). Keep out of reach of children.Effects of Missed Dosage of MagaldrateTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MagaldrateGive symptomatic and supportive treatment.Methyl Polysiloxane
About Methyl PolysiloxaneSiloxanes, Antiflatulent.Mechanism of Action of Methyl PolysiloxaneMethyl Polysiloxane relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus.
Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas.Pharmacokinets of Methyl PolysiloxaneN/AOnset of Action for Methyl PolysiloxaneN/ADuration of Action for Methyl PolysiloxaneN/AHalf Life of Methyl PolysiloxaneN/ASide Effects of Methyl PolysiloxaneN/AContra-indications of Methyl PolysiloxaneHypersensitivity to Methyl PolysiloxaneSpecial Precautions while taking Methyl PolysiloxaneKidney failurePregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Methyl Polysiloxane1. Flatulent dyspepsia
2. Postoperative distension
3. Gastric Distention
4. Functional digestive disorders
5. Stomach pain
6. Burning
7. Nausea and excess gas (dyspepsia)
Interactions for Methyl PolysiloxaneN/ATypical Dosage for Methyl Polysiloxane125 - 166 mg taken half an hour before food.
Methyl Polysiloxane in a coated chewing gum: 5 mg - 200 mg per piece of coated gum.
With an antacid: 20 mg -50 mg of Methyl Polysiloxane
Schedule of Methyl PolysiloxaneN/AStorage Requirements for Methyl PolysiloxaneStored at room temperature (15-30?C) away from moisture and heat.Effects of Missed Dosage of Methyl PolysiloxaneTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Methyl PolysiloxaneGive symptomatic and supportive treatment.About N/AMechanism of Action of N/APharmacokinets of N/AOnset of Action for N/ADuration of Action for N/AHalf Life of N/ASide Effects of N/AContra-indications of N/ASpecial Precautions while taking N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for N/AInteractions for N/ATypical Dosage for N/ASchedule of N/AStorage Requirements for N/AEffects of Missed Dosage of N/AEffects of Overdose of N/AHome Delivery for Magaldrate + Methyl Polysiloxane + Oxethazaine in Your City
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