Polydimethyl Siloxane Pharmacology

Polydimethyl Siloxane

About Polydimethyl Siloxane
Polymeric organosilicon compound(silicone), Antiflatulent.
Mechanism of Action of Polydimethyl Siloxane
Polydimethyl Siloxane relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus.
Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas. Polydimethyl Siloxane is occasionally called as Dimethicone. The most common antigas material is Dimethicone and when mixed with silicone dioxide becomes Simethicone. Simethicone is also referred to as activated Dimethicone. Simethicone is the most common antigas material and may be the only drug approved antiflatulent.
As the antacid chewing tablet is chewed, the active antacid and antiflatulent in the gum coating is released into the saliva and ingested to give relief from gastrointestinal disturbances in the gastro-intestinal tract.
Besides its antigas effect, Simethicone used in a gum coating can also improve the smoothness of the coating. Activated Dimethicone helps to relieve pain and bloating caused by trapped wind.
Pharmacokinets of Polydimethyl Siloxane
N/A
Onset of Action for Polydimethyl Siloxane
N/A
Duration of Action for Polydimethyl Siloxane
N/A
Half Life of Polydimethyl Siloxane
N/A
Side Effects of Polydimethyl Siloxane
N/A
Contra-indications of Polydimethyl Siloxane
Hypersensitivity to Polydimethyl Siloxane
Special Precautions while taking Polydimethyl Siloxane
Kidney failure
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Polydimethyl Siloxane
1. Flatulent dyspepsia
2. Postoperative distension
3. Gastric Distention
4. Functional digestive disorders
5. Stomach pain
6. Burning
7. Nausea and excess gas (dyspepsia)
Interactions for Polydimethyl Siloxane
N/A
Typical Dosage for Polydimethyl Siloxane
125 - 166 mg taken half an hour before food.
Polydimethyl Siloxane in a coated chewing gum: 5 mg - 200 mg per piece of coated gum.
With an antacid: 20 mg -50 mg of Polydimethyl Siloxane
Schedule of Polydimethyl Siloxane
N/A
Storage Requirements for Polydimethyl Siloxane
Stored at room temperature (15-30?C) away from moisture and heat.
Effects of Missed Dosage of Polydimethyl Siloxane
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Polydimethyl Siloxane
Give symptomatic and supportive treatment.

Home Delivery for Polydimethyl Siloxane in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including polydimethyl siloxane.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for polydimethyl siloxane and other medicines and health products. Home delivery services for polydimethyl siloxane may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take polydimethyl siloxane only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for polydimethyl siloxane before they complete the sale. You can get this information while placing the order for polydimethyl siloxane with the pharmacy.

Polydimethyl Siloxane is a generic medicine name and there are several brands available for it. Some of the brands for polydimethyl siloxane might be better known than polydimethyl siloxane itself. If the pharmacy that's willing to deliver medicines to your home doesn't have polydimethyl siloxane in stock, you can ask for one of the branded alternatives for polydimethyl siloxane.