Chlormezanone Pharmacology

Chlormezanone

About Chlormezanone

A non-benzodiazepine derivative,indirect GABA-A agonist, Anxiolytic, Antipsychotics and Central muscle relaxant.

Mechanism of Action of Chlormezanone

Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways.

Pharmacokinets of Chlormezanone

N/A

Onset of Action for Chlormezanone

15-30 min

Duration of Action for Chlormezanone

6 - 8 hrs

Half Life of Chlormezanone

N/A

Side Effects of Chlormezanone

1. Drowsiness
2. Weakness
3. Nausea
4. Dizziness
5. Abdominal pain
6. Cerebral oedema
7. Renal tubular necrosis
8. Hyperglycemia
9. Hypoglycemia
10. Liver damage
11. Encephalopathy
12. Coma
13. Death

Contra-indications of Chlormezanone

1. Hypersensitivity to the patient

Special Precautions while taking Chlormezanone

1. Impaired hepatic function
2. Renal impairment

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Chlormezanone

1. Painful muscle spasm associated with trauma
2. Lumbago
3. Inflammatory & degenerative processes
4. Neuritic vasomotor pain
5. Premenstrual tension
6. Dysmenorrhea
7. Musculoskeletal disorders

Interactions for Chlormezanone

Alcohol or other CNS depressants like barbiturates, narcotics: Additive effects.

Typical Dosage for Chlormezanone

Oral-
Adults-
100 - 200 mg thrice daily.
Children (5-12 years) -
50-100mg 3-4 times daily.
Preparations are available in combination with other analgesic and anti-inflammatory drugs.

Schedule of Chlormezanone

Storage Requirements for Chlormezanone

Store at room temperature, away from heat and direct light. Keep out of the reach of children.

Effects of Missed Dosage of Chlormezanone

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Chlormezanone

Give symptomatic and supportive treatment.

Home Delivery for Chlormezanone in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including chlormezanone.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for chlormezanone and other medicines and health products. Home delivery services for chlormezanone may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take chlormezanone only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for chlormezanone before they complete the sale. You can get this information while placing the order for chlormezanone with the pharmacy.

Chlormezanone is a generic medicine name and there are several brands available for it. Some of the brands for chlormezanone might be better known than chlormezanone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have chlormezanone in stock, you can ask for one of the branded alternatives for chlormezanone.