Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor Pharmacology

Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor

About Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
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Mechanism of Action of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
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Pharmacokinets of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Onset of Action for Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Duration of Action for Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Half Life of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
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Side Effects of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Contra-indications of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Special Precautions while taking Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Pregnancy Related Information
Contraindicated; since Capsaicin is contraindicated in pregnancy.So the combination generic cannot be used in pregnancy.
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated; since Capsaicin is contraindicated in breast feeding.So the combination generic cannot be used in lactating mother.
Children Related Information
N/A
Indications for Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
1.Muscle relaxant
2.Analgesic
Interactions for Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Typical Dosage for Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
Apply the medicament to the affected area when necessary.
Schedule of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Storage Requirements for Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Effects of Missed Dosage of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A
Effects of Overdose of Capsaicin + Methyl salicylate + Menthol + Eucalyptus oil + Camphor
N/A

Capsaicin

About Capsaicin
A lipophilic capsaicinoid(methyl vanillyl nonenamide),substance P release inducer, A topical analgesic ,antineuralgic and antipruritic, rubefacient.
Mechanism of Action of Capsaicin
Capsaicin is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.
Capsaicin depletes the neurochemical substance P which transmits pain and desensitizes person to pain. Capsaicin produces a temporary reduction in pain.
Pharmacokinets of Capsaicin
N/A
Onset of Action for Capsaicin
N/A
Duration of Action for Capsaicin
N/A
Half Life of Capsaicin
N/A
Side Effects of Capsaicin
1.Warm
2.Stinging
3.Burning
4.Skin redness
Contra-indications of Capsaicin
Hypersensitivity to Capsaicin
Special Precautions while taking Capsaicin
1.Wear gloves when applying cream.
2.Do not apply after a hot bath or shower or use it with a heating pad.
3.Avoid contact with eyes, mucus membranes or broken skin
4.Broken or irritated skin
5.Prolonged use
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Below 2 years:Contraindicated
Indications for Capsaicin
1.Back pain
2.Bursitis
3.Fibromyalgia
4.Joint pain
5.Muscle pain
6.Nerve Pain
7.Osteoarthritis
8.Pain due to diabetic neuropathy
9.Post-herpetic neuralgia
10.Post-surgical neuropathic pain
Interactions for Capsaicin
N/A
Typical Dosage for Capsaicin
Topical
For neuralgia or itching of the skin:
Adults: Apply 0.025% cream 3 or 4 times a day and rub well and if sufficient response is not obtained apply 0.075% cream.
Children: Same as adult dose
Below 2 years: Contraindicated
Schedule of Capsaicin
N/A
Storage Requirements for Capsaicin
Store the medicine in a closed container at room temperature. Keep away from heat, moisture and direct light. Keep out of the reach of children.
Effects of Missed Dosage of Capsaicin
Apply the missed dose as soon as remember and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the doses.
Effects of Overdose of Capsaicin
Give supportive measures and symptomatic treatment.

Methyl salicylate

About Methyl salicylate
Salicylates, Rubefacient, counterirritant.
Mechanism of Action of Methyl salicylate
Methyl salicylate is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.
Pharmacokinets of Methyl salicylate
N/A
Onset of Action for Methyl salicylate
N/A
Duration of Action for Methyl salicylate
N/A
Half Life of Methyl salicylate
N/A
Side Effects of Methyl salicylate
N/A
Contra-indications of Methyl salicylate
N/A
Special Precautions while taking Methyl salicylate
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Methyl salicylate
N/A
Interactions for Methyl salicylate
N/A
Typical Dosage for Methyl salicylate
N/A
Schedule of Methyl salicylate
N/A
Storage Requirements for Methyl salicylate
N/A
Effects of Missed Dosage of Methyl salicylate
N/A
Effects of Overdose of Methyl salicylate
N/A

Menthol

About Menthol
Terpenes and terpenoid, Antipruritic, decongestant, topical analgesic.
Mechanism of Action of Menthol
Menthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and mild local anaesthetic effect relieves itching. It has good soothing effect and acts as a demulcent. It also acts as a carminative.
Pharmacokinets of Menthol
N/A
Onset of Action for Menthol
N/A
Duration of Action for Menthol
N/A
Half Life of Menthol
N/A
Side Effects of Menthol
1.Irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
12.Contact dermatitis
13.Allergic reactions
Contra-indications of Menthol
1. Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Menthol
1.Should not apply Menthol directly in to or near the nostrils of small children or asthma patients
2.Prolonged use
3.Seizures
4.Should not take steam inhalation orally
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
below 2 years: Contraindicated
Indications for Menthol
1. Rubefacient.
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5.Sore throat
6.Cold sores
7.Hay fever
8.As an inhalant to relieve nasal, bronchial, or upper respiratory congestion
9.Sinusitis
10.Bronchial cough
11.Pharyngeal inflammation
Interactions for Menthol
N/A
Typical Dosage for Menthol
Dosage individualized based on requirements of the patient.
Lozenges: Dissolve lozenge (5%-10% menthol) slowly in the mouth hourly as needed by the patients.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Menthol (3.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1tsp of solution for each pint, up to thrice daily
Schedule of Menthol
N/A
Storage Requirements for Menthol
Store at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.
Effects of Missed Dosage of Menthol
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Menthol
Provide symptomatic treatment and supportive measures.

Eucalyptus oil

About Eucalyptus oil
Essential oil derived from eucalyptus leaves, Topical decongestant, antiseptic, insect repellent and biopesticide.
Mechanism of Action of Eucalyptus oil
Eucalyptus oil is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.
Pharmacokinets of Eucalyptus oil
N/A
Onset of Action for Eucalyptus oil
N/A
Duration of Action for Eucalyptus oil
N/A
Half Life of Eucalyptus oil
N/A
Side Effects of Eucalyptus oil
N/A
Contra-indications of Eucalyptus oil
N/A
Special Precautions while taking Eucalyptus oil
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Eucalyptus oil
N/A
Interactions for Eucalyptus oil
N/A
Typical Dosage for Eucalyptus oil
N/A
Schedule of Eucalyptus oil
N/A
Storage Requirements for Eucalyptus oil
N/A
Effects of Missed Dosage of Eucalyptus oil
N/A
Effects of Overdose of Eucalyptus oil
N/A

Camphor

About Camphor
N/A
Mechanism of Action of Camphor
Camphor acts as a rubefacient when it is rubbed on the skin and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and a mild local anaesthetic effect and relieves itching. When ingested in small amounts, it creates feelings of warmth and comfort in the epigastrium. Camphor acts as a local anesthetic on the respiratory passageways and causing cough suppression.
Pharmacokinets of Camphor
Absorption: Well absorbed through the skin, Distribution: Widely distributed in the body and crosses the placenta, Metabolism: Metabolized in liver, Excretion: Excreted mainly through urine and a minor portion is excreted through lungs.
Onset of Action for Camphor
N/A
Duration of Action for Camphor
N/A
Half Life of Camphor
N/A
Side Effects of Camphor
1.Gastric irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
Contra-indications of Camphor
1.Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Camphor
1.Should not apply camphor directly in to or near the nostrils of small children or asthma patients
2.Prolonged use may lead to accumulation in adipose tissue
3.Seizures.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Children (below 2 years): Contraindicated
Indications for Camphor
1.Rubefacient
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5. As balm for chapped lips, cold sores
6.As an inhalant to relieve nasal, bronchial or upper respiratory congestion.
Interactions for Camphor
N/A
Typical Dosage for Camphor
Dosage individualized based on requirement and condition of the patient.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Camphor (6.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1 tsp of solution for each pint, up to thrice daily.
Schedule of Camphor
N/A
Storage Requirements for Camphor
Store at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.
Effects of Missed Dosage of Camphor
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Camphor
Provide symptomatic treatment and supportive measures.
Ingestion: If camphor has been ingested recently, and the condition of the patient allows, perform gastric lavage. If only small amounts have been ingested, administer cathartics.
Inhalation: If camphor has been inhaled, remove patient from exposure, administer fresh air or oxygen, and establish respiration.
Topical: If there has been external contact with camphor, wash skin thoroughly with soap and water. Irrigate eyes with plenty of water.
In severe poisoning: Assist respiration in respiratory depression. Perform artificial respiration if required. Treat convulsions with diazepam or other suitable drugs. Protect the airway by endotracheal intubation or suitable measures, Perform gastric lavage and reduce absorption by administration of activated charcoal, and then a saline cathartic if required. Resin and charcoal haemoperfusion may be used in severe cases.

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