Dimethindene Maleate Pharmacology

Dimethindene Maleate

About Dimethindene Maleate
A first generation histamine H1 antagonist, Antipruritic, anti-allergic agent.
Mechanism of Action of Dimethindene Maleate
This drug blocks the receptors of histamine (H1 receptors) centrally and peripherally. This results the inhibition of activation and allergic symptoms produced by histamines. The drug also have some antimuscarinic and serotonic receptor antagonistic action
Pharmacokinets of Dimethindene Maleate
N/A
Onset of Action for Dimethindene Maleate
Below 60min
Duration of Action for Dimethindene Maleate
6-8 hrs
Half Life of Dimethindene Maleate
N/A
Side Effects of Dimethindene Maleate
1. Sedation
2. CNS excitation
3. Dryness of mouth
4. Thickened respiratory mucus
5. Urinary retention
6. Constipation
7. Tachycardia
8. Arrhythmia
9. Blurred vision
10. Blood dyscriasis
Contra-indications of Dimethindene Maleate
1. Hypersensitivity to the drug
2. Asthma
3. Urinary retention
4. Paralytic ileus
Special Precautions while taking Dimethindene Maleate
1. Any work which require mental alertness such as driving and machine operations
2. Closed angle glaucoma
3. Epilepsy
4. GIT obstruction
Pregnancy Related Information
Contraindicated.
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
NEONATES- Contraindicated
Indications for Dimethindene Maleate
1. Allergic dermatitis
2. Pruritis
3. Ocular allergies
4. Urticaria
5. Angioedema
6. Rhinitis
7. Conjunctivitis
Interactions for Dimethindene Maleate
Alchohol & other CNS depressants like barbiturates, analgesics, sedatives, neuroleptics: CNS depressant effect enhanced.
MAOIs, Atropine & TCAs: Antimuscarinic effect enhanced.
Aminoglycosides: Ototoxicity masked, irreversible damage may occur.
Typical Dosage for Dimethindene Maleate
Oral-
Adult-1 tab for 1-3 times daily
Children (>6yrs) - 1 tab 3 times daily
Children (<6yrs) -1/2 tab 1-3 times daily

Schedule of Dimethindene Maleate
N/A
Storage Requirements for Dimethindene Maleate
Store in a cool dark place.Protect from heat and light.Keep out of the reach of children.
Effects of Missed Dosage of Dimethindene Maleate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose
Effects of Overdose of Dimethindene Maleate
Give symptomatic and supportive treatment

Home Delivery for Dimethindene Maleate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dimethindene maleate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dimethindene maleate and other medicines and health products. Home delivery services for dimethindene maleate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take dimethindene maleate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dimethindene maleate before they complete the sale. You can get this information while placing the order for dimethindene maleate with the pharmacy.

Dimethindene Maleate is a generic medicine name and there are several brands available for it. Some of the brands for dimethindene maleate might be better known than dimethindene maleate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dimethindene maleate in stock, you can ask for one of the branded alternatives for dimethindene maleate.