Acrivastine Pharmacology

Acrivastine

About Acrivastine
A Second Generation Histamine H1 Antagonist, Alkylamine derivative, Antihistaminic.
Mechanism of Action of Acrivastine
Acrivastine medicine contains the active ingredient Acrivastine, which is a type of medicine called a non-sedating antihistamine. It works by preventing the actions of histamine. Histamine is a substance produced by the body as part of its defense mechanisms. It is stored in cells called mast cells, in almost all tissues of the body. When the body reacts to a foreign substance (known as an allergen, eg flower pollen), the mast cells stimulated by the allergen release their stores of histamine. The released histamine then binds to its receptors (H1 receptors), causing a chain reaction that results in allergic symptoms. It causes an increase in blood flow to the area of the allergy, and the release of other chemicals that add to the allergic response and results in allergic reaction. In hay fever and other nasal allergies (allergic rhinitis), histamine causes inflammation of the nose, eyes, skin or airways and results in itchy watery eyes, a runny nose, sneezing and nasal congestion. Acrivastine works by blocking histamine H1 receptors. It does not prevent the actual release of histamine from mast cells, but prevents it binding to its receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of nasal allergies such as hay fever. Acrivastine can also be used to relieve the symptoms of various itchy rashes and hives. Blocking the actions of histamine relieves the itching and reduces the rash. Acrivastine is called a non-sedating antihistamine as it does not enter the brain, and is therefore unlikely to cause drowsiness. However, people react differently to medicines and extremely rarely some people may experience some drowsiness.

Pharmacokinets of Acrivastine
N/A
Onset of Action for Acrivastine
N/A
Duration of Action for Acrivastine
N/A
Half Life of Acrivastine
N/A
Side Effects of Acrivastine
1.Drowsiness
2.Headache
3.Difficulty urinating
4.Dry mouth
5.Blurred vision
6.Abdominal upset
7.Dizziness
8.Confusion
Contra-indications of Acrivastine
Hypersensitivity to Acrivastine
Special Precautions while taking Acrivastine
1.Hepatic impairment
2.Kidney impairment
3.Epilepsy
4.Porphyria
5.Prostatic hypertrophy
6.Urinary retention
7.Glaucoma
8.Pyloroduodenal obstruction
Pregnancy Related Information
use with caution
Old Age Related Information
Contraindicated
Breast Feeding Related Information
use with caution
Children Related Information
Below 12 years:Contraindicated
Indications for Acrivastine
1.Allergy (urticaria, hay fever)
Interactions for Acrivastine
N/A
Typical Dosage for Acrivastine
Adult:24mg/day in 3 divided doses
Children:
Above 12 years:same as adult dose
Below 12years:Contraindicated
Schedule of Acrivastine
N/A
Storage Requirements for Acrivastine
Store at 15 - 30 degree C. Keep out of the reach of children
Effects of Missed Dosage of Acrivastine
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Acrivastine
Give supportive measures and treatment.

Home Delivery for Acrivastine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including acrivastine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for acrivastine and other medicines and health products. Home delivery services for acrivastine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take acrivastine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for acrivastine before they complete the sale. You can get this information while placing the order for acrivastine with the pharmacy.

Acrivastine is a generic medicine name and there are several brands available for it. Some of the brands for acrivastine might be better known than acrivastine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have acrivastine in stock, you can ask for one of the branded alternatives for acrivastine.