Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol Pharmacology

Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

About Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Mechanism of Action of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Pharmacokinets of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Onset of Action for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Duration of Action for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Half Life of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Side Effects of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Contra-indications of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Special Precautions while taking Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Interactions for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Typical Dosage for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Schedule of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Storage Requirements for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Effects of Missed Dosage of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Effects of Overdose of Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol

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Guaiphenesin

About Guaiphenesin

Propanediol derivative, Expectorant.

Mechanism of Action of Guaiphenesin

Guaiphenesin is an expectorant which after absorption from the gastrointestinal tract secreted by tracheobronchial glands and directly increase bronchial secretion and mucosal ciliary action. It increases respiratory tract fluid by reducing adhesiveness and surface tension, reducing viscosity of the secretions and there by facilitating their removal and clears chest congestion.
Action in local vaginal preparations: Guaiphenesin helps to thin the thick or sticky cervical mucus.

Pharmacokinets of Guaiphenesin

Absorption: Well absorbed orally.Distribution: It is secreted by the tracheobronchial glands.
Metabolism: It is metabolized primarily to Beta-2-methoxyphenoxy-lactic acid. Excretion: It is excreted in the urine.

Onset of Action for Guaiphenesin

N/A

Duration of Action for Guaiphenesin

N/A

Half Life of Guaiphenesin

60 minutes

Side Effects of Guaiphenesin

1. Headache
2. Dizziness
3. Nausea
4. Vomiting
5. Rash
6. Diarrhoea
7. Drowsiness
8. Stomach pain

Contra-indications of Guaiphenesin

1. Hypersensitivity to the drug
2. Chronic or persistent cough associated with chronic lower respiratory tract diseases
3. Asthma
4. Bronchitis
5. Chronic obstructive pulmonary disease (COPD)
6. Emphysema

Special Precautions while taking Guaiphenesin

1. Porphyria

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

May be used

Indications for Guaiphenesin

1. Expectorant
2. Thick or sticky cervical mucus

Interactions for Guaiphenesin

N/A

Typical Dosage for Guaiphenesin

Oral :
Adults and children over 12 years: 100 to 400mg up to 6 times daily as required.Maximum dose: 2.4g/day
Children (age 6 to 11): 100 to 200mg up to 6 times daily as required.Maximum dose: 1.2g/day
Children (age 2 to 5): 50 to 100mg up to 6 times daily as required.Maximum dose: 600mg/day
Extended release:
Adults and children over 12 years: 600 to 1200mg twice daily. Not to exceed 2.4g in 24 hours
Children (age 6 to 12): 600mg twice daily. Not to exceed 1.2g in 24 hours
Children (age 2 to 6): 300mg twice daily. Not to exceed 600mg in 24 hours
Thick or sticky cervical mucus: 200mg 2 to 3 times daily from 4 days prior to ovulation and continue through ovulation day.

Schedule of Guaiphenesin

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Storage Requirements for Guaiphenesin

Store at a temperature below 30 degree C. Keep out of reach of children.

Effects of Missed Dosage of Guaiphenesin

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Guaiphenesin

Provide symptomatic treatment and supportive measures.

Phenylpropanolamine

About Phenylpropanolamine

Alfa-and Beta-adrenergic agonist, Phenethylamine derivative, a stimulant, decongestant,anorectic.

Mechanism of Action of Phenylpropanolamine

It is a mixed acting sympathomimetic amine with predominant alpha adrenergic agonistic action. It exerts nasal decongestant action by acting through alpha adrenergic receptors in the respiratory tract mucosa; and produces vasoconstriction. It temporarily reduces the swelling associated with inflammation of nasal mucosa.
Phenylpropanolamine also suppresses the appetite control center in the hypothalamus

Pharmacokinets of Phenylpropanolamine

Absorption: Well absorbed orally, Metabolism: Metabolized in to an active metabolite in liver, Excretion: Excreted mainly through urine.

Onset of Action for Phenylpropanolamine

15 to 30 minutes

Duration of Action for Phenylpropanolamine

3 hours

Half Life of Phenylpropanolamine

N/A

Side Effects of Phenylpropanolamine

1. Hypertension
2. Stroke
3. Arrhythmias
4. Renal failure
5. Rhabdomyolysis
6. Psychotic disturbances
7. Hallucinations
8. Seizures

Contra-indications of Phenylpropanolamine

1. Hypersensitivity to Phenylpropanolamine or other sympathomimetics
2. Coronary artery disease
3. Hypertension
4. Arteriosclerosis
5. Depression
6. Angle-closure glaucoma
7. Diabetes
8. Renal impairment
9. Hyperthyroidism
10. During or within 14 days of use of MAO inhibitors
11. Use as an anorexiant for children less than 12 years of age
12. Sustained-release forms during lactation and in children less than 12 years of age

Special Precautions while taking Phenylpropanolamine

1. Cardiovascular disorders
2. Mild Hypertension
3. Prostatic hypertrophy
4. Psychosis or other psychiatric disorders (Phenylpropanolamine may precipitate psychiatric disorders)
5. Not drinking large amounts of caffeine-containing beverages, such as coffee, tea, or colas
6. Do not engage in driving, using machines, or doing anything else that requires mental alertness while taking medication
7. Inform the physician if cold symptoms do not improve within 7 days or if fever is present

Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Phenylpropanolamine

1. Nasal congestion

Interactions for Phenylpropanolamine

N/A

Typical Dosage for Phenylpropanolamine

Oral:
Adults:
As decongestant: 25mg every four hours or 50mg every 8 hours daily. Not to exceed 150mg/day
Anorexiant: 25mg thrice daily; 30minutes before meals.
Extended release tablets or capsules:As decongestant: 75mg twice daily
Anorexiant: 75mg once daily in the morning.
As decongestant:
Children (6 to 12 years): 12.5mg up to every four hours. Not to exceed 75mg/day
Children (2 to 6years): 6.25mg up to every four hours. Not to exceed 37.5mg/day

Schedule of Phenylpropanolamine

Storage Requirements for Phenylpropanolamine

Store at controlled room temperature at range of 15 to 30 degree C.; in a well closed container. Protect from light.

Effects of Missed Dosage of Phenylpropanolamine

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Phenylpropanolamine

Provide symptomatic treatment and supportive measures.Remove drug from the body by induced emesis or gastric lavage. Barbiturate sedatives are sometimes used to control excessive CNS stimulation. Monitor Cardiovascular and respiratory functions. Administer intravenous fluids to control hypotension. Correct hypertension with Intravenous phentolamine or nitrates. Perform forced diuresis by acidification of urine.

Chlorpheniramine Maleate

About Chlorpheniramine Maleate

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Mechanism of Action of Chlorpheniramine Maleate

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Pharmacokinets of Chlorpheniramine Maleate

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Onset of Action for Chlorpheniramine Maleate

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Duration of Action for Chlorpheniramine Maleate

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Half Life of Chlorpheniramine Maleate

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Side Effects of Chlorpheniramine Maleate

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Contra-indications of Chlorpheniramine Maleate

First Generation alkylamine H1 Antagonist, Antihistamine.

Special Precautions while taking Chlorpheniramine Maleate

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Chlorpheniramine Maleate

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Interactions for Chlorpheniramine Maleate

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Typical Dosage for Chlorpheniramine Maleate

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Schedule of Chlorpheniramine Maleate

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Storage Requirements for Chlorpheniramine Maleate

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Effects of Missed Dosage of Chlorpheniramine Maleate

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Effects of Overdose of Chlorpheniramine Maleate

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Ambroxol

About Ambroxol

Active N-desmethyl metabolite of bromhexine,systemically active mucolytic agent, Secretomotoric and expectoration improver.

Mechanism of Action of Ambroxol

Ambroxol hydrochloride acts as an expectoration improver and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and by breaking network of fibres in tenacious sputum . It induces thin copious bronchial secretion and possesses antioxidant properties.

Pharmacokinets of Ambroxol

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Onset of Action for Ambroxol

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Duration of Action for Ambroxol

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Half Life of Ambroxol

N/A

Side Effects of Ambroxol

1. Rhinorrhoea
2. Lacrimations
3. Allergic reactions
4. Gastric irritation.

Contra-indications of Ambroxol

Hypersensitivity to the Ambroxol hydrochloride or Bromhexine.

Special Precautions while taking Ambroxol

1.Hepatic impairment
2.Renal impairment
3.Gastric and duodenal ulcer
4.Convulsive disorders

Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Use with caution

Indications for Ambroxol

1. As Expectorant and mucolytic
2. Conditions associated with production of viscid mucous
3. Bronchitis
4. Pharyngitis
5. Laryngitis
6. Rhinitis
7. Sinusitis
8. Asthmatic bronchitis
9. Mucous bronchiectasis
10. Chronic Pneumonia.

Interactions for Ambroxol

N/A

Typical Dosage for Ambroxol

Oral: 15mg to 30mg three times daily.
Children (6 to 12years): 5ml 2 to 3 times daily
Children (2 to 6years): 2.5ml thrice daily. (5ml liquid contains 30mg Ambroxol hydrochloride)
Children up to 2 years: 7.5mg two times daily

Schedule of Ambroxol

Storage Requirements for Ambroxol

Store in a cool dry place and protect from light. Keep out of reach of children.

Effects of Missed Dosage of Ambroxol

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Ambroxol

Provide symptomatic treatment and supportive measures.

Home Delivery for Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for guaiphenesin + phenylpropanolamine + chlorpheniramine maleate + ambroxol and other medicines and health products. Home delivery services for guaiphenesin + phenylpropanolamine + chlorpheniramine maleate + ambroxol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

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Guaiphenesin + Phenylpropanolamine + Chlorpheniramine Maleate + Ambroxol is a generic medicine name and there are several brands available for it. Some of the brands for guaiphenesin + phenylpropanolamine + chlorpheniramine maleate + ambroxol might be better known than guaiphenesin + phenylpropanolamine + chlorpheniramine maleate + ambroxol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have guaiphenesin + phenylpropanolamine + chlorpheniramine maleate + ambroxol in stock, you can ask for one of the branded alternatives for guaiphenesin + phenylpropanolamine + chlorpheniramine maleate + ambroxol.