Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate Pharmacology

Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

About Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Mechanism of Action of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Pharmacokinets of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Onset of Action for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Duration of Action for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Half Life of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Side Effects of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Contra-indications of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Special Precautions while taking Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Pregnancy Related Information

Contraindicated: since Dextromethorphan and Chlorpheniramine maleate are contraindicated in pregnancy the combination generic cannot be used in pregnancy.

Old Age Related Information

N/A

Breast Feeding Related Information

Contraindicated; since Dextromethorphan, Guaiphensin and Chlorpheniramine maleate are contraindicated in breast feeding the combination generic cannot be used in breast feeding mother.

Children Related Information

N/A

Indications for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

It is a combination of antitussive (Dextromethorpan), expectorant (Guaiphensin and Ammonium chloride) and decongestatnt (Chlorpheniramine Maleate).
1.Cough
2.Rhinitis
3.Bronchitis

Interactions for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

N/A

Typical Dosage for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

Oral
Adult: 5 - 10 ml to be taken every 6 - 8 hours
Children: 5 ml to be taken every 8 - 12 hours.

Schedule of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Storage Requirements for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Effects of Missed Dosage of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Effects of Overdose of Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate

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Dextromethorphan

About Dextromethorphan

A synthetic morphine (((dextrorotatory methyl ether of Levorphanol))) derivative,A synthetic narcotic antitussive.

Mechanism of Action of Dextromethorphan

Dextromethorphan hydrobromide is a selective antitussive which raises threshold of cough centre and suppresses the cough reflex by direct action on the cough centre in the medulla. It does not depress mucociliary function of the airway mucosa and is also devoid of constipating and addicting actions. (((Its antitussive action is not exerted through opioid receptors)))

Pharmacokinets of Dextromethorphan

Absorption: Well absorbed orally, Metabolism: Extensively metabolized by liver, Excretion: Excreted primarily through urine as metabolites; about 7 to 10% is excreted through faeces.

Onset of Action for Dextromethorphan

Below ? an hour

Duration of Action for Dextromethorphan

3 to 6 hours

Half Life of Dextromethorphan

11 hours

Side Effects of Dextromethorphan

1. Dizziness
2. Nausea
3. Vomiting
4. Stomach pain
5. Drowsiness
6. Ataxia.

Contra-indications of Dextromethorphan

Patients currently taking MAO inhibitors or within two weeks of discontinuing MAO inhibitors.

Special Precautions while taking Dextromethorphan

1. Atopic children
2. Sedated or deliberate patients
3. Those patients confined to the supine position
4. Patients sensitive to aspirin

Pregnancy Related Information

Contraindicated

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

May be used
Children below 2 years: Syrup, tablets, or lozenges are contraindicated

Indications for Dextromethorphan

Chronic nonproductive cough.

Interactions for Dextromethorphan

N/A

Typical Dosage for Dextromethorphan

Oral:
Chronic nonproductive cough:
Adults and children above 12 years: 10 to 20mg every 4 hours; or 30mg three to four times daily.
Maximum dose: 120mg daily.
Children (((age 6 to 12))): 5 to 10mg every four hours
Maximum dose: 60mg daily
Children (((age 2 to 6))): 2.5 to 5mg every four hours.
Maximum dose: 30mg daily.

Schedule of Dextromethorphan

N/A

Storage Requirements for Dextromethorphan

Store at room temperature in a well closed light resistant container. Protect from excess heat and moisture. Keep out of reach of children.

Effects of Missed Dosage of Dextromethorphan

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Dextromethorphan

Remove drug from the body by administration of activated charcoal and provide symptomatic treatment and supportive measures.

Guaiphenesin

About Guaiphenesin

Propanediol derivative, Expectorant.

Mechanism of Action of Guaiphenesin

Guaiphenesin is an expectorant which after absorption from the gastrointestinal tract secreted by tracheobronchial glands and directly increase bronchial secretion and mucosal ciliary action. It increases respiratory tract fluid by reducing adhesiveness and surface tension, reducing viscosity of the secretions and there by facilitating their removal and clears chest congestion.
Action in local vaginal preparations: Guaiphenesin helps to thin the thick or sticky cervical mucus.

Pharmacokinets of Guaiphenesin

Absorption: Well absorbed orally.Distribution: It is secreted by the tracheobronchial glands.
Metabolism: It is metabolized primarily to Beta-2-methoxyphenoxy-lactic acid. Excretion: It is excreted in the urine.

Onset of Action for Guaiphenesin

N/A

Duration of Action for Guaiphenesin

N/A

Half Life of Guaiphenesin

60 minutes

Side Effects of Guaiphenesin

1. Headache
2. Dizziness
3. Nausea
4. Vomiting
5. Rash
6. Diarrhoea
7. Drowsiness
8. Stomach pain

Contra-indications of Guaiphenesin

1. Hypersensitivity to the drug
2. Chronic or persistent cough associated with chronic lower respiratory tract diseases
3. Asthma
4. Bronchitis
5. Chronic obstructive pulmonary disease (COPD)
6. Emphysema

Special Precautions while taking Guaiphenesin

1. Porphyria

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

May be used

Indications for Guaiphenesin

1. Expectorant
2. Thick or sticky cervical mucus

Interactions for Guaiphenesin

N/A

Typical Dosage for Guaiphenesin

Oral :
Adults and children over 12 years: 100 to 400mg up to 6 times daily as required.Maximum dose: 2.4g/day
Children (age 6 to 11): 100 to 200mg up to 6 times daily as required.Maximum dose: 1.2g/day
Children (age 2 to 5): 50 to 100mg up to 6 times daily as required.Maximum dose: 600mg/day
Extended release:
Adults and children over 12 years: 600 to 1200mg twice daily. Not to exceed 2.4g in 24 hours
Children (age 6 to 12): 600mg twice daily. Not to exceed 1.2g in 24 hours
Children (age 2 to 6): 300mg twice daily. Not to exceed 600mg in 24 hours
Thick or sticky cervical mucus: 200mg 2 to 3 times daily from 4 days prior to ovulation and continue through ovulation day.

Schedule of Guaiphenesin

N/A

Storage Requirements for Guaiphenesin

Store at a temperature below 30 degree C. Keep out of reach of children.

Effects of Missed Dosage of Guaiphenesin

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Guaiphenesin

Provide symptomatic treatment and supportive measures.

Ammonium chloride

About Ammonium chloride

Ammonium compound, Acidifier,Expectorant.

Mechanism of Action of Ammonium chloride

N/A

Pharmacokinets of Ammonium chloride

N/A

Onset of Action for Ammonium chloride

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Duration of Action for Ammonium chloride

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Half Life of Ammonium chloride

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Side Effects of Ammonium chloride

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Contra-indications of Ammonium chloride

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Special Precautions while taking Ammonium chloride

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Ammonium chloride

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Interactions for Ammonium chloride

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Typical Dosage for Ammonium chloride

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Schedule of Ammonium chloride

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Storage Requirements for Ammonium chloride

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Effects of Missed Dosage of Ammonium chloride

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Effects of Overdose of Ammonium chloride

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Chlorpheniramine Maleate

About Chlorpheniramine Maleate

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Mechanism of Action of Chlorpheniramine Maleate

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Pharmacokinets of Chlorpheniramine Maleate

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Onset of Action for Chlorpheniramine Maleate

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Duration of Action for Chlorpheniramine Maleate

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Half Life of Chlorpheniramine Maleate

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Side Effects of Chlorpheniramine Maleate

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Contra-indications of Chlorpheniramine Maleate

First Generation alkylamine H1 Antagonist, Antihistamine.

Special Precautions while taking Chlorpheniramine Maleate

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Chlorpheniramine Maleate

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Interactions for Chlorpheniramine Maleate

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Typical Dosage for Chlorpheniramine Maleate

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Schedule of Chlorpheniramine Maleate

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Storage Requirements for Chlorpheniramine Maleate

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Effects of Missed Dosage of Chlorpheniramine Maleate

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Effects of Overdose of Chlorpheniramine Maleate

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Home Delivery for Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate and other medicines and health products. Home delivery services for dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate before they complete the sale. You can get this information while placing the order for dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate with the pharmacy.

Dextromethorphan + Guaiphenesin + Ammonium chloride + Chlorpheniramine Maleate is a generic medicine name and there are several brands available for it. Some of the brands for dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate might be better known than dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate in stock, you can ask for one of the branded alternatives for dextromethorphan + guaiphenesin + ammonium chloride + chlorpheniramine maleate.