Temazepam Pharmacology

Temazepam

About Temazepam
Benzodiazepine derivative, Sedative ? hypnotic,anti-anxiety, anticonvulsant, skeletal muscle relaxant.
Mechanism of Action of Temazepam
Temazepam mainly acts on Limbic system and ascending reticular formation in the CNS and binds to the BZD receptor. The binding will facilitates GABA mediated chloride channel opening and produce hyperpolarisation. This will produce an increase in the concentration of the inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neuron. These in turn alters normal functions of the body. Temazepam works by acting on receptors in the brain called GABA receptors. This causes the release of an inhibitory neurotransmitter called GABA in the brain. GABA inhibits many of the activities of the brain. Temazepam increases total sleep time and relieves from insomnia.
Pharmacokinets of Temazepam
Absorption:It is well absorbed after oral administration.Distribution:It is widely distributed mainly in protein bound form.Metabolism:It undergoes metabolism the liver.Excretion:Excreted mainly in the urine.
Onset of Action for Temazepam
30 - 60minutes
Duration of Action for Temazepam
N/A
Half Life of Temazepam
4 - 20 hours
Side Effects of Temazepam
1.Dizziness
2.Headache
3.Drowsiness
4.Lethargy
5.Vertigo
6.Blurred vision
7.Nausea
8.Diarrhoea
9.Dry mouth
10.Nervousness
11.Fatigue
Contra-indications of Temazepam
Hypersensitivity to Temazepam and other Benzodiazepines
Special Precautions while taking Temazepam
1.Renal impairment
2.Hepatic impairment
3.Pulmonary insufficiency
4.Suicidal tendencies
5.Drug abuse
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Temazepam
Insomnia
Interactions for Temazepam
N/A
Typical Dosage for Temazepam
Adult: 7.5mg to be taken 30minutes before bedtime. Dose can be gradually increased up to 30mg if needed.
Schedule of Temazepam
N/A
Storage Requirements for Temazepam
The drug should be kept at 15 - 30 degree C in a tightly closed container.Keep out of the reach of children.
Effects of Missed Dosage of Temazepam
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.
Effects of Overdose of Temazepam
Give support and symptomatic treatment. Flumazenil can be given as antagonist. Hypotension can be treated with vasopressors.If the patient is conscious induce emesis followed by charcoal administration

Home Delivery for Temazepam in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including temazepam.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for temazepam and other medicines and health products. Home delivery services for temazepam may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take temazepam only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for temazepam before they complete the sale. You can get this information while placing the order for temazepam with the pharmacy.

Temazepam is a generic medicine name and there are several brands available for it. Some of the brands for temazepam might be better known than temazepam itself. If the pharmacy that's willing to deliver medicines to your home doesn't have temazepam in stock, you can ask for one of the branded alternatives for temazepam.