Telmisartan Pharmacology

Telmisartan

About Telmisartan
Angiotensin II Receptor antagonist, Antihypertensive.
Mechanism of Action of Telmisartan
It is a competitive antagonist of angiotensin-2 at AT-1 receptor. It decreases peripheral resistance and lowers BP in hypertensive individuals. It blocks all overt actions of angiotensin-2 such as: - 1. Vasoconstriction, 2. Central & Peripheral sympathetic stimulus, 3. Release of aldosterone and adrenaline, 4. Salt and water reabsorption, 5. Central actions like thirst, vasopressin release, and growth promoting actions on heart and blood vessels.
Pharmacokinets of Telmisartan
Absorption: Absorbed orally, bioavailability is about 42% Distribution: It is distributed in to the body in a highly protein bound form, Metabolism: Metabolized by glucuronide conjugation in to an inactive metabolite. Excretion: Excreted mainly through faeces and rest is excreted through urine.
Onset of Action for Telmisartan
N/A
Duration of Action for Telmisartan
24 hours
Half Life of Telmisartan
24 hours
Side Effects of Telmisartan
1.Dizziness
2.Headache
3.Coughing
4.Edema
5.Nausea
6.Abdominal pain
7.Diarrhoea
8.Dyspepsia
9.Pharyngitis
10.Sinusitis
11.Upper respiratory tract infections
12.Urinary tract infections
13.Elevated liver enzymes
14.Weakness
15.Chest pain
16.Myalgia
17.Back pain
18.Neutropenia
19.Fetopathic
20.Precipitate renal failure in renal artery stenosis, and in insufficient renal blood flow
21.Urticaria
22.Rashes
23.Hyperkalemia

Contra-indications of Telmisartan
Hypersensitivity to the drug
Special Precautions while taking Telmisartan
1.Renal impairment
2.Hepatic impairment
3.Heart failure
4.Aortic or mitral valve stenosis
5.Obstructive cardiomyopathy
6.Use cautiously in volume depleted and salt depleted individuals, these conditions should be corrected before starting the therapy
7.Patient should be cautiously involve in driving or operating heavy machinery during therapy
8.Avoid alcohol or use with caution during therapy
9.Use with caution in hyperkalemia and along with potassium sparing diuretics

Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Telmisartan
1.Hypertension
Interactions for Telmisartan
N/A
Typical Dosage for Telmisartan
40mg once daily
Maintenance dose: 20 to 80mg once daily

Schedule of Telmisartan
H
Storage Requirements for Telmisartan
Store at room temperature at a range of 15 to 30 degree C. protects from direct heat and light and store in a tightly closed container. Do not remove blisters until just before taking tablets


Effects of Missed Dosage of Telmisartan
Take the missed dose as soon as remember; if it is the time of next dose then skip the missed dose and take the regular dose
Effects of Overdose of Telmisartan
Treatment is supportive and symptomatic. If hypotension occur kept patient in supine position and if required give I.V. infusion of normal saline

Home Delivery for Telmisartan in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including telmisartan.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for telmisartan and other medicines and health products. Home delivery services for telmisartan may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take telmisartan only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for telmisartan before they complete the sale. You can get this information while placing the order for telmisartan with the pharmacy.

Telmisartan is a generic medicine name and there are several brands available for it. Some of the brands for telmisartan might be better known than telmisartan itself. If the pharmacy that's willing to deliver medicines to your home doesn't have telmisartan in stock, you can ask for one of the branded alternatives for telmisartan.