Satranidazole Pharmacology

Satranidazole

About Satranidazole

Nitroimidazole derivative, Anti-protozoal.

Mechanism of Action of Satranidazole

Satranidazole is nitro imidazoles which have broad spectrum cidal activity against Protozoa and some anaerobic bacteria. Its selective toxicity to anaerobic microbes involves 1. Drug enters the cell by diffusion, 2. Nitro group of drug is reduced by redox proteins present only in anaerobic organisms to reactive nitro radical which excerts cytotoxic action by damaging DNA and other critical biomolecules. 3.DNA helix destabilization &strand breakage has been observed.

Pharmacokinets of Satranidazole

Absorption: Well absorbed orally, Distribution: Widely distributed,
Metabolism: Metabolized in liver, Excretion: Excreted in urine.

Onset of Action for Satranidazole

N/A

Duration of Action for Satranidazole

12 hours

Half Life of Satranidazole

14 hours

Side Effects of Satranidazole

1.Headache
2.Dizziness
3.Dry mouth
4.Weakness

Contra-indications of Satranidazole

1.Hypersensitivity to the drug
2.Blood dyscrasias

Special Precautions while taking Satranidazole

N/A

Pregnancy Related Information

Contraindicated

Old Age Related Information

May be used

Breast Feeding Related Information

Contraindicated

Children Related Information

Use with caution
Neonates: Contraindicated

Indications for Satranidazole

1.Amoebiasis
2.Giardiasis
3.Trichomonas vaginitis
4.Anaerobic bacterial infections

Interactions for Satranidazole

Alcohol: It does not produce any disulfiram-like reaction with alcohol.

Typical Dosage for Satranidazole

Amoebiasis:
300mg 12hourly for 5 days
Giardiasis and Trichomoniasis:
600mg as a single dose

Schedule of Satranidazole

Storage Requirements for Satranidazole

Store in a well closed container and protect from light. Keep out of the reach of children.

Effects of Missed Dosage of Satranidazole

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Satranidazole

Treatment is supportive & symptomatic.

Home Delivery for Satranidazole in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including satranidazole.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for satranidazole and other medicines and health products. Home delivery services for satranidazole may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take satranidazole only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for satranidazole before they complete the sale. You can get this information while placing the order for satranidazole with the pharmacy.

Satranidazole is a generic medicine name and there are several brands available for it. Some of the brands for satranidazole might be better known than satranidazole itself. If the pharmacy that's willing to deliver medicines to your home doesn't have satranidazole in stock, you can ask for one of the branded alternatives for satranidazole.