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- Pharmacology For Clindamycin Topical + Miconazole + Lactobacillus
Clindamycin Topical + Miconazole + Lactobacillus Pharmacology
Clindamycin Topical + Miconazole + Lactobacillus
About Clindamycin Topical + Miconazole + LactobacillusN/AMechanism of Action of Clindamycin Topical + Miconazole + LactobacillusN/APharmacokinets of Clindamycin Topical + Miconazole + LactobacillusN/AOnset of Action for Clindamycin Topical + Miconazole + LactobacillusN/ADuration of Action for Clindamycin Topical + Miconazole + LactobacillusN/AHalf Life of Clindamycin Topical + Miconazole + LactobacillusN/ASide Effects of Clindamycin Topical + Miconazole + LactobacillusN/AContra-indications of Clindamycin Topical + Miconazole + LactobacillusN/ASpecial Precautions while taking Clindamycin Topical + Miconazole + LactobacillusN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicatedChildren Related InformationN/AIndications for Clindamycin Topical + Miconazole + LactobacillusVaginal infectionsInteractions for Clindamycin Topical + Miconazole + LactobacillusN/ATypical Dosage for Clindamycin Topical + Miconazole + LactobacillusN/ASchedule of Clindamycin Topical + Miconazole + LactobacillusN/AStorage Requirements for Clindamycin Topical + Miconazole + LactobacillusN/AEffects of Missed Dosage of Clindamycin Topical + Miconazole + LactobacillusN/AEffects of Overdose of Clindamycin Topical + Miconazole + LactobacillusN/AClindamycin Topical
About Clindamycin TopicalMacrolide, Lincosamide Antibiotic (Topical).Mechanism of Action of Clindamycin TopicalIt binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie:they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl t RNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.Pharmacokinets of Clindamycin TopicalAbsorption: It is minimally absorbed after topical application.Onset of Action for Clindamycin TopicalN/ADuration of Action for Clindamycin TopicalN/AHalf Life of Clindamycin TopicalN/ASide Effects of Clindamycin Topical1.Burning
2.Stinging
3.Dryness
4.Redness
5.Oiliness
6.Itching
7.Mild irritation
Contra-indications of Clindamycin Topical1.Hypersensitive to Clindamycin
Special Precautions while taking Clindamycin Topical1. Avoid contact with eyes, nose, mouth, and lips and if medication gets in any of these areas, wash with water
2.Avoid use of medicament to broken or irritated skin
3. Avoid using other topical products on the same area at the same
4.History of enteritis, ulcerative colitis, or antibiotic-associated colitis
Pregnancy Related InformationUse with caution.Old Age Related InformationMay be usedBreast Feeding Related InformationUse with caution.Children Related InformationUse with caution.Indications for Clindamycin Topical1.Acne vulgarisInteractions for Clindamycin TopicalN/ATypical Dosage for Clindamycin TopicalApply once daily to washed and dried areas for maximum of 15 minutes initially and increase the exposure graduallySchedule of Clindamycin TopicalN/AStorage Requirements for Clindamycin TopicalThe drug should be store at room temperature.Keep out of reach of children.Effects of Missed Dosage of Clindamycin TopicalApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Clindamycin TopicalGive supportive measures and symptomatic treatment.Miconazole
About MiconazoleAn imidazole derivative, Broad spectrum Antifungal.Mechanism of Action of MiconazoleMiconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesisPharmacokinets of MiconazoleAbsorption: Oral absorption of Miconazole is poor. Distribution: It is distributed in the body in protein bound form Metabolism: It undergoes metabolism in the liver. Excretion: It is excreted in urine and faeces.Onset of Action for MiconazoleN/ADuration of Action for MiconazoleN/AHalf Life of Miconazole1 daySide Effects of Miconazole1.Vulvovaginal burning
2.Burning
3.Irritation
4.Pruritis
5.Maceration
6.Dermatitis Contra-indications of Miconazole1.Hypersensitivity to Miconazole and other Azole antifungalsSpecial Precautions while taking Miconazole1.Hepatic dysfunctionPregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
NEONATES: contraindicated
Indications for Miconazole1.Tinea versicolor
2.Vulvovaginal candidiasis
3.Tinea pedis
4.Tinea corporis
5.Tinea cruris
6.Otomycosis
7.Onychomycosis
8.Oral candidiasis
9.Intestinal candidiasis
10.Diaper dermatitisInteractions for MiconazoleBenzoyl peroxide: Antibacterial synergism. Typical Dosage for MiconazoleAdult: Topical use:
Cutaneous infections: Apply the cream twice daily on the affected part for about 1 month
Tinea versicolor: Apply the cream once daily on the affected part
Vaginal use: Insert 300 mg suppository at bed time for 3 days or Insert 100 mg suppository at bed time for 7 days
CHILDREN:
Topical use:
Cutaneous infections: Apply the cream twice daily on the affected part for about 1 month
Tinea vericolor: Apply the cream once daily on the affected part
Schedule of MiconazoleHStorage Requirements for MiconazoleThe drug should be stored at 15 - 30 degree C.Effects of Missed Dosage of MiconazoleTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of MiconazoleGive supportive measures and treatment.
Lactobacillus
About LactobacillusLactic acid bacteria, Probiotic,Antidiarrhoeal.Mechanism of Action of LactobacillusLactobacillus is a probiotic and it is called as friendly bacteria. It is used along with antibiotic in order to restore the body`s natural microbial flora with in the digestive tract. Lactobacillus helps in the breakdown of food and leads to the production of lactic acid, hydrogen peroxide and other byproducts. This will alter the intestinal pH and that make the environment hostile for pathogens.Pharmacokinets of LactobacillusAbsorption: It is orally well absorbed after oral administration.
Onset of Action for LactobacillusN/ADuration of Action for LactobacillusN/AHalf Life of LactobacillusN/ASide Effects of Lactobacillus1.Abdominal discomfort
2.Vaginal irritation (when used vaginally)
Contra-indications of Lactobacillus1.Recent bowel surgery
2.Intestinal damage
3.Weakened immune system
Special Precautions while taking LactobacillusPatient on Inulin treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Use with cautionIndications for Lactobacillus1.Aphthous stomatitis
2.Hypochlorhydria
3.Hepatic encephalopathy
4.Adjuvant to antibiotic therapy
5.Diarrhoea.Interactions for LactobacillusN/ATypical Dosage for LactobacillusAdult: 60 - 150 million spores 3 times daily depending on the severity of infections.
Vaginal bacterial infections: 1- 2 billion bacteria 2 - 3 times daily
Suppositories:
Vaginal infections, cystitis: 1 - 2 suppositories are inserted in to vagina at night for 2 weeks. Each suppository contains 1 - 2 billion lactobacilli
Schedule of LactobacillusN/AStorage Requirements for LactobacillusRefrigerate below 5 degree C.Effects of Missed Dosage of LactobacillusN/AEffects of Overdose of LactobacillusGive supportive measures and symptomatic treatmentHome Delivery for Clindamycin Topical + Miconazole + Lactobacillus in Your City
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Clindamycin Topical + Miconazole + Lactobacillus is a generic medicine name and there are several brands available for it. Some of the brands for clindamycin topical + miconazole + lactobacillus might be better known than clindamycin topical + miconazole + lactobacillus itself. If the pharmacy that's willing to deliver medicines to your home doesn't have clindamycin topical + miconazole + lactobacillus in stock, you can ask for one of the branded alternatives for clindamycin topical + miconazole + lactobacillus.