Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin Pharmacology

Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin

About Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Mechanism of Action of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
ATP:ATP has the significance for all the metabolic processes in living beings, including spermatozoa, as they are the principal donors of energy in all the reactions of biosynthesis.ATP is produced more through the process of Glycolysis than through the process of Oxidative Phosphorylation in Human Spermatozoa..ATP broken down to Adenosine in the liver positively crosses the BTB to contribute in the process of Quality spermatogenesis..Direct supplementation of ATP improves sperm and semen parameters..ATP enhances sperm motility and Fertilization potential of spermatozoa.

IDEBENONE:Idebenone with its similar molecular structure to Co-enzyme Q10 exhibits superior Antioxidant properties due to its increased H+ atoms .Idebenone does not get oxidized under anaerobic conditions and provides superior antioxidant support during Spermatogenesis.Idebenone helps in recycling of Vit E and other antioxidants more efficiently when compared to Co-enzyme Q10 and thus prevents lipid peroxidation and hence can be more useful in maintaining Sperm Membrane Integrity and Fertilization Potential of Spermatozoa.Idebenone inhibits excessive Catecholamine release from the Adrenal medulla in smokers to prevent damage of seminiferous tubules specially in men with Varicocele wherein there is a retrograde flow of blood carrying Catecholamines from the adrenal gland to the testis through the spermatic vein.
L-Arginine:Inhibits Somatostatin and enhances HGH to help in antiaging of all glands including Testes. Helps in Glycolytic ATP production for sperm motility.Regulates Spermatogenesis .Required for the formation of Putrescine, Spermadine & Spermine in Spermatozoa during spermatogenesis.
Selenium:Selenium forms sperm seleno proteins required for sperm tail stability and thereby helps in motility. Influences Leydig cells for the production of Testosterone
Proanthocyanidin:Is a potent antioxidant that is 50 times more powerful than Vit E.20 times more powerful than Vit C and effectively prevents oxidative damage to spermatozoa and enhances the defense mechanism of seminal plasma to protect and nourish spermatozoa.

Pharmacokinets of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Onset of Action for Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Duration of Action for Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Half Life of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Side Effects of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Contra-indications of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Special Precautions while taking Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Pregnancy Related Information
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Old Age Related Information
N/A
Breast Feeding Related Information
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Children Related Information
N/A
Indications for Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
Idiopathic Oligo Asthenospermia
Interactions for Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
N/A
Typical Dosage for Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
One capsule thrice daily for a period of 90 days to form a Complete Course or as directed by physician.
Schedule of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
N/A
Storage Requirements for Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Effects of Missed Dosage of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Effects of Overdose of Idebenone + L-Arginine + Zinc Sulphate + Selenium + Proanthocyanidin
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Idebenone

About Idebenone
Antioxidant
Mechanism of Action of Idebenone
Idebenone with its similar molecular structure to Co-enzyme Q10 exhibits superior Antioxidant properties due to its increased H+ atoms.
Pharmacokinets of Idebenone
N/A
Onset of Action for Idebenone
N/A
Duration of Action for Idebenone
N/A
Half Life of Idebenone
N/A
Side Effects of Idebenone
1.Gastrointestinal disturbances
2.Dizziness
3.Headaches
4.Anxiety
5.Uneasiness
6.Sleep alterations
Contra-indications of Idebenone
Hypersensitivity
Special Precautions while taking Idebenone
N/A
Pregnancy Related Information
Contraindicated
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Idebenone
1.Treatment of mental impairment associated with cerebrovascular disorders like dementia and Alzheimer's.
2.Anti-ageing and as an antioxidant
Interactions for Idebenone
N/A
Typical Dosage for Idebenone
The usual recommended dosage for adults is 90 mg/day in divided dose.
Schedule of Idebenone
N/A
Storage Requirements for Idebenone
N/A
Effects of Missed Dosage of Idebenone
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Effects of Overdose of Idebenone
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L-Arginine

About L-Arginine
Proteinogenic , a-amino acid, Essential amino acid.
Mechanism of Action of L-Arginine
L-arginine is converted in the body into a chemical called nitric oxide. Nitric oxide causes blood vessels to open wider for improved blood flow. L-arginine also stimulates the release of growth hormone, insulin, and other substances in the body.
Pharmacokinets of L-Arginine
N/A
Onset of Action for L-Arginine
N/A
Duration of Action for L-Arginine
N/A
Half Life of L-Arginine
N/A
Side Effects of L-Arginine
1.Abdominal pain
2.Bloating
3.Diarrhea
4.Gout
5.Blood abnormalities
6.Allergies
7.Airway inflammation
8.Worsening of asthma
9.Low blood pressure.
Contra-indications of L-Arginine
N/A
Special Precautions while taking L-Arginine
1.Allergies or asthma: L-arginine can cause an allergic response or make swelling in the airways worse. If you decide to take L-arginine, use it with caution.
2.Herpes: There is a concern that L-arginine might make herpes worse. There is some evidence that L-arginine is needed for the herpes virus to multiply.
3.Low blood pressure: L-arginine might lower blood pressure. This could be a problem if you already have low blood pressure.
4.Recent heart attack: There is a concern that L-arginine might increase the risk of death after a heart attack, especially in older people. If you have had a heart attack recently, don?t take L-arginine.
5.Surgery: L-arginine might affect blood pressure. There is a concern that it might interfere with blood pressure control during and after surgery. Stop taking L-arginine at least 2 weeks before a scheduled surgery.
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for L-Arginine
1.Angina
2.Erectile Dysfunction
3.Congestive Heart Failure
Interactions for L-Arginine
1.L-arginine seems to decrease blood pressure. Taking L-arginine along with medications for high blood pressure might cause your blood pressure to go too low.
2.Medications that increase blood flow to the heart (Nitrates) interacts with L-ARGININE
3.Sildenafil (Viagra) can lower blood pressure. L-arginine can also lower blood pressure
Typical Dosage for L-Arginine
1.For congestive heart failure: doses range from 6-20 grams per day, as three divided doses.
2.For chest pain associated with coronary artery disease (angina pectoris): 3-6 grams three times per day for up to one month.
3.For preventing the loss of the effectiveness of nitroglycerin in relieving pain in people with chest pain due to coronary artery disease (angina pectoris): 700 mg four times daily.
4.For organic erectile dysfunction (ED): 5 grams per day. Taking lower doses might not be effective.
5.For preventing inflammation of the digestive tract in premature infants: 261 mg/kg added to oral feedings daily for the first 28 days of life.
Schedule of L-Arginine
N/A
Storage Requirements for L-Arginine
N/A
Effects of Missed Dosage of L-Arginine
N/A
Effects of Overdose of L-Arginine
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Zinc Sulphate

About Zinc Sulphate
Zinc compound, An astringent , Adjunctive treatment of Wilson?s disease.
Mechanism of Action of Zinc Sulphate
N/A
Pharmacokinets of Zinc Sulphate
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Onset of Action for Zinc Sulphate
N/A
Duration of Action for Zinc Sulphate
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Half Life of Zinc Sulphate
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Side Effects of Zinc Sulphate
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Contra-indications of Zinc Sulphate
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Special Precautions while taking Zinc Sulphate
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Zinc Sulphate
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Interactions for Zinc Sulphate
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Typical Dosage for Zinc Sulphate
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Schedule of Zinc Sulphate
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Storage Requirements for Zinc Sulphate
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Effects of Missed Dosage of Zinc Sulphate
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Effects of Overdose of Zinc Sulphate
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Selenium

About Selenium
A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.
Mechanism of Action of Selenium
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Pharmacokinets of Selenium
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Onset of Action for Selenium
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Duration of Action for Selenium
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Half Life of Selenium
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Side Effects of Selenium
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Contra-indications of Selenium
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Special Precautions while taking Selenium
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Selenium
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Interactions for Selenium
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Typical Dosage for Selenium
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Schedule of Selenium
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Storage Requirements for Selenium
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Effects of Missed Dosage of Selenium
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Effects of Overdose of Selenium
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Proanthocyanidin

About Proanthocyanidin
Flavanoid,antioxidant
Mechanism of Action of Proanthocyanidin
Antioxidant: neutralizing free radicals, blocking lipid peroxidation and stabilizing cell membranes.

Inhibit the destruction of collagen by stabilizing the activity of 1-antitrypsin. 1-antitrypsin inhibits the actions of destructive enzymes.

Inhibit the release of histamine and prostaglandins.

Inhibit platelet aggregation.
Pharmacokinets of Proanthocyanidin
N/A
Onset of Action for Proanthocyanidin
N/A
Duration of Action for Proanthocyanidin
N/A
Half Life of Proanthocyanidin
N/A
Side Effects of Proanthocyanidin
N/A
Contra-indications of Proanthocyanidin
N/A
Special Precautions while taking Proanthocyanidin
1.Proanthocyanidins inhibit platelet aggregation, and thus patients with bleeding disorders should use with caution.
2.Patients should not use grape see extract for more than 14 days before surgery.
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Proanthocyanidin
1.To prevent coronary heart disease (CHD), stroke, and to strengthen capillaries and improve circulation to the extremities.
2.To treat conditions associated with vascular function such as diabetes mellitus, varicose veins, impotence, and tingling in the arms and legs.
Interactions for Proanthocyanidin
Caution should be used in patients who are taking anticoagulants, aspirin, and anti-platelet drugs.
Typical Dosage for Proanthocyanidin
100-300mg per day
Schedule of Proanthocyanidin
N/A
Storage Requirements for Proanthocyanidin
N/A
Effects of Missed Dosage of Proanthocyanidin
N/A
Effects of Overdose of Proanthocyanidin
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