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- Pharmacology For Triprolidine + Dextromethorphan
Triprolidine + Dextromethorphan Pharmacology
Triprolidine + Dextromethorphan
About Triprolidine + DextromethorphanN/AMechanism of Action of Triprolidine + DextromethorphanN/APharmacokinets of Triprolidine + DextromethorphanN/AOnset of Action for Triprolidine + DextromethorphanN/ADuration of Action for Triprolidine + DextromethorphanN/AHalf Life of Triprolidine + DextromethorphanN/ASide Effects of Triprolidine + DextromethorphanN/AContra-indications of Triprolidine + DextromethorphanN/ASpecial Precautions while taking Triprolidine + DextromethorphanN/APregnancy Related InformationContraindicatedOld Age Related InformationMay be usedBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Triprolidine + DextromethorphanAllergic coughInteractions for Triprolidine + DextromethorphanN/ATypical Dosage for Triprolidine + DextromethorphanN/ASchedule of Triprolidine + DextromethorphanN/AStorage Requirements for Triprolidine + DextromethorphanN/AEffects of Missed Dosage of Triprolidine + DextromethorphanN/AEffects of Overdose of Triprolidine + DextromethorphanN/ATriprolidine
About TriprolidineFirst generation histamine H1 antagonist, Alkylamine derivative, Antihistamine.Mechanism of Action of TriprolidineTriprolidine hydrochloride exerts it`s action by acting as an H1 receptor antagonist. It antagonizes most of the pharmacological actions of Histamine and reduces allergic symptoms. It also has anticholinergic properties and reduces secretions
Pharmacokinets of TriprolidinePharmacokinetics: Absorption: Well absorbed orally, Distribution: Widely distributed in the body, Metabolism: Metabolized in the body by carboxylation in to metabolites,
Excretion: Excreted through urine.Onset of Action for TriprolidineN/ADuration of Action for TriprolidineN/AHalf Life of TriprolidineN/ASide Effects of Triprolidine1. Sedation
2. Inability to concentrate
3. Diminished alertness
4. Motor incordination
5. Fatigue
6. Insomnia
7. Somnolence
8. Dry mouth
9. Urinery hesitancy
10. Alterd bowel movement
11. Orthostatic hypotension
12. Palpitations
13. Tachycardia
14. Drowsiness
15. Dizziness
16. Excitation
17. Headache
18. Nervousness
19. Blurred vision
20. Nasal stuffiness
21. Anorexia
22. Epigastric distress
23. Nausea
24. Vomiting
25. Diarrhea
26. Constipation
27. Thickening of bronchial secretions
Contra-indications of Triprolidine1. Hypersensitivity to the drug
2. Coronary insufficiency
3. Hypertension
4. Prostatism
5. Thyrotoxicosis
6. Bladder dysfunction
7. Narrow angle glaucoma
8. Phaeochromocytoma
9. Asthma
Special Precautions while taking Triprolidine1. Driving or any work requiring mental alertness
2. Peptic ulcer
3. Pyloroduodenal obstruction
4. Prostatic hypertrophy
5. Bladder neck obstruction
6. Urinary retention
7. Increased intraocular pressure
8. Hyperthyroidism
9. Sleep apnea
10. Cardiovascular disease
11. Along with other medication
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Triprolidine1. Common cold
2. Allergic respiratory diseases
3. Runny nose
4. Sneezing
5. Itchy nose and throat
6. Itchy,watery eyes
7. Cough
Interactions for TriprolidineN/ATypical Dosage for TriprolidineOral: 2.5 to 5mg dosage forms are availableSchedule of TriprolidineGStorage Requirements for TriprolidineStore at room temperature at a range of 15 to 30 degree C. Protect from light, heat, and moisture.Effects of Missed Dosage of TriprolidineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of TriprolidineProvide symptomatic treatment and supportive measures. Dextromethorphan
About DextromethorphanA synthetic morphine (((dextrorotatory methyl ether of Levorphanol))) derivative,A synthetic narcotic antitussive.Mechanism of Action of DextromethorphanDextromethorphan hydrobromide is a selective antitussive which raises threshold of cough centre and suppresses the cough reflex by direct action on the cough centre in the medulla. It does not depress mucociliary function of the airway mucosa and is also devoid of constipating and addicting actions. (((Its antitussive action is not exerted through opioid receptors)))Pharmacokinets of DextromethorphanAbsorption: Well absorbed orally, Metabolism: Extensively metabolized by liver, Excretion: Excreted primarily through urine as metabolites; about 7 to 10% is excreted through faeces.Onset of Action for DextromethorphanBelow ? an hourDuration of Action for Dextromethorphan3 to 6 hoursHalf Life of Dextromethorphan11 hoursSide Effects of Dextromethorphan1. Dizziness
2. Nausea
3. Vomiting
4. Stomach pain
5. Drowsiness
6. Ataxia.Contra-indications of DextromethorphanPatients currently taking MAO inhibitors or within two weeks of discontinuing MAO inhibitors.Special Precautions while taking Dextromethorphan1. Atopic children
2. Sedated or deliberate patients
3. Those patients confined to the supine position
4. Patients sensitive to aspirin
Pregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationMay be used
Children below 2 years: Syrup, tablets, or lozenges are contraindicated
Indications for DextromethorphanChronic nonproductive cough.Interactions for DextromethorphanN/ATypical Dosage for DextromethorphanOral:
Chronic nonproductive cough:
Adults and children above 12 years: 10 to 20mg every 4 hours; or 30mg three to four times daily.
Maximum dose: 120mg daily.
Children (((age 6 to 12))): 5 to 10mg every four hours
Maximum dose: 60mg daily
Children (((age 2 to 6))): 2.5 to 5mg every four hours.
Maximum dose: 30mg daily.
Schedule of DextromethorphanN/AStorage Requirements for DextromethorphanStore at room temperature in a well closed light resistant container. Protect from excess heat and moisture. Keep out of reach of children.Effects of Missed Dosage of DextromethorphanTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DextromethorphanRemove drug from the body by administration of activated charcoal and provide symptomatic treatment and supportive measures.Home Delivery for Triprolidine + Dextromethorphan in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for triprolidine + dextromethorphan and other medicines and health products. Home delivery services for triprolidine + dextromethorphan may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take triprolidine + dextromethorphan only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for triprolidine + dextromethorphan before they complete the sale. You can get this information while placing the order for triprolidine + dextromethorphan with the pharmacy.
Triprolidine + Dextromethorphan is a generic medicine name and there are several brands available for it. Some of the brands for triprolidine + dextromethorphan might be better known than triprolidine + dextromethorphan itself. If the pharmacy that's willing to deliver medicines to your home doesn't have triprolidine + dextromethorphan in stock, you can ask for one of the branded alternatives for triprolidine + dextromethorphan.