- Medicine India
- Generic Medicines
- I
- Pharmacology For Iron (Ferrous Ascorbate) + Folic Acid
Iron (Ferrous Ascorbate) + Folic Acid Pharmacology
Iron (Ferrous Ascorbate) + Folic Acid
About Iron (Ferrous Ascorbate) + Folic AcidN/AMechanism of Action of Iron (Ferrous Ascorbate) + Folic AcidN/APharmacokinets of Iron (Ferrous Ascorbate) + Folic AcidN/AOnset of Action for Iron (Ferrous Ascorbate) + Folic AcidN/ADuration of Action for Iron (Ferrous Ascorbate) + Folic AcidN/AHalf Life of Iron (Ferrous Ascorbate) + Folic AcidN/ASide Effects of Iron (Ferrous Ascorbate) + Folic Acid1.Stomach cramps
2.Constipation
3.Heartburn
4.Nausea
5.Vomiting
6.Iron may impact the stools by turning them black
Contra-indications of Iron (Ferrous Ascorbate) + Folic Acid1.Pernicious anaemia
2.Intestinal diverticula or any intestinal obstruction
3.Hemochromatosis and hemosiderosis
4.Patients receiving repeated blood transfusions
5.Concomitant parenteral iron therapy
Special Precautions while taking Iron (Ferrous Ascorbate) + Folic AcidN/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Iron (Ferrous Ascorbate) + Folic Acid1.For prevention and treatment of iron deficiency anaemia in pregnancy and to supply maintainance dosage of folic acid
2.Treatment of iron deficiency concomitant with folic acid deficiency in non pregnant patients
Interactions for Iron (Ferrous Ascorbate) + Folic AcidN/ATypical Dosage for Iron (Ferrous Ascorbate) + Folic AcidN/ASchedule of Iron (Ferrous Ascorbate) + Folic AcidN/AStorage Requirements for Iron (Ferrous Ascorbate) + Folic AcidN/AEffects of Missed Dosage of Iron (Ferrous Ascorbate) + Folic AcidTake the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.Effects of Overdose of Iron (Ferrous Ascorbate) + Folic AcidAn overdose of iron with folic acid supplements may pose serious health risks.Symptoms of an overdose include paleness, weak and quick heartbeat, nausea, vomiting and green diarrhea. It is important to ensure that dosages of these supplements be taken correctly to avoid potential problems.If an over dosage is suspected,contact immediate medical help.
Iron (Ferrous ascorbate)
About Iron (Ferrous ascorbate)Fe II Salt of iron,oral iron formulation ,antianaemic,heamatinic.Mechanism of Action of Iron (Ferrous ascorbate)Addition of ascorbic acid converts the ferric form to ferrous form thus making it absorbable from duodenum and upper jejunum, resulting in considerable enhancement of the absorption of iron. It has been demonstrated that Fe(II) ascorbate is less easily oxidized than Fe(II) in ferrous sulphate. Absorption of ferrous ascorbate averaged 52% higher than ferrous sulphate in subjects with ID. (Marx et al., 1982) Thus when administered as ferrous ascorbate, Fe(II) salt is more resistant to oxidation at alkaline pH,delivers maximum amount of ferrous iron to the duodenal brush border and at the same time produces minimum GI adverse effects.Pharmacokinets of Iron (Ferrous ascorbate)1.Absorption:Increased in iron deficiency anaemia
2.Distribution:Transported in a transferring bound form to bone marrow
3.Elimination:Excretion is minimal
Onset of Action for Iron (Ferrous ascorbate)N/ADuration of Action for Iron (Ferrous ascorbate)N/AHalf Life of Iron (Ferrous ascorbate)N/ASide Effects of Iron (Ferrous ascorbate)1.Nausea
2.Vomiting
3.Constipation
4.Diarrhea
5.Abdominal pain
Contra-indications of Iron (Ferrous ascorbate)1.Hyper sensitivity
2.Haemolytic anaemia unless iron deficiency anaemia is present
3.Haemochromatosis
4.Haemosiderosis
5.Peptic ulcer
6.Regional enteritis
7.Ulcerative colitis
8.Those receiving repeated blood transfution
Special Precautions while taking Iron (Ferrous ascorbate)N/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Iron (Ferrous ascorbate)Prevention and treatment of Iron Deficiency Anemia in pregnant women and children.Interactions for Iron (Ferrous ascorbate)N/ATypical Dosage for Iron (Ferrous ascorbate)Ferrous ascorbate equivalent to 100 mg elemental iron is used for the treatment of Iron Deficiency Anemia in pregnancy and 30 to 60 mg is used as a prophylaxis for iron deficiency anemia in pregnancy, and also for treatment of iron deficiency anemia in children.Schedule of Iron (Ferrous ascorbate)N/AStorage Requirements for Iron (Ferrous ascorbate)N/AEffects of Missed Dosage of Iron (Ferrous ascorbate)Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
Effects of Overdose of Iron (Ferrous ascorbate)Symptoms: Nausea, vomiting, abdominal pain, diarrhea, haematemesis and rectal bleeding. Hypotension, coma and hepatocellular necrosis may occur later.
Treatment: Empty stomach contents by gastric lavage within 1 hr of ingestion. In severe toxicity, IV desferrioxamine may be given. Whole bowel irrigation may also be considered in severe poisoning.
Folic Acid
About Folic AcidDietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.Mechanism of Action of Folic AcidFolic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.Pharmacokinets of Folic AcidAbsorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic AcidOral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic AcidOral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic AcidN/ASide Effects of Folic AcidN/AContra-indications of Folic AcidN/ASpecial Precautions while taking Folic Acid1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Folic Acid1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic AcidOral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic AcidC1 (Oral)
C (Parenteral)
Storage Requirements for Folic AcidStore at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.Effects of Missed Dosage of Folic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Folic AcidRelatively non toxic. Provide symptomatic treatment and supportive measures.Home Delivery for Iron (Ferrous Ascorbate) + Folic Acid in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including iron (ferrous ascorbate) + folic acid.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for iron (ferrous ascorbate) + folic acid and other medicines and health products. Home delivery services for iron (ferrous ascorbate) + folic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take iron (ferrous ascorbate) + folic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for iron (ferrous ascorbate) + folic acid before they complete the sale. You can get this information while placing the order for iron (ferrous ascorbate) + folic acid with the pharmacy.
Iron (Ferrous Ascorbate) + Folic Acid is a generic medicine name and there are several brands available for it. Some of the brands for iron (ferrous ascorbate) + folic acid might be better known than iron (ferrous ascorbate) + folic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron (ferrous ascorbate) + folic acid in stock, you can ask for one of the branded alternatives for iron (ferrous ascorbate) + folic acid.