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- Pharmacology For Econazole + Triamcinolone acetonide
Econazole + Triamcinolone acetonide Pharmacology
Econazole + Triamcinolone acetonide
About Econazole + Triamcinolone acetonideN/AMechanism of Action of Econazole + Triamcinolone acetonideN/APharmacokinets of Econazole + Triamcinolone acetonideN/AOnset of Action for Econazole + Triamcinolone acetonideN/ADuration of Action for Econazole + Triamcinolone acetonideN/AHalf Life of Econazole + Triamcinolone acetonideN/ASide Effects of Econazole + Triamcinolone acetonide1.Burning
2.Itching
Contra-indications of Econazole + Triamcinolone acetonideN/ASpecial Precautions while taking Econazole + Triamcinolone acetonideN/APregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Econazole + Triamcinolone acetonideSkin infectionsInteractions for Econazole + Triamcinolone acetonideN/ATypical Dosage for Econazole + Triamcinolone acetonideN/ASchedule of Econazole + Triamcinolone acetonideN/AStorage Requirements for Econazole + Triamcinolone acetonideStore in a well closed container at temperature between 15 to 30 degree celcius. Keep out of the reach of children.Effects of Missed Dosage of Econazole + Triamcinolone acetonideN/AEffects of Overdose of Econazole + Triamcinolone acetonideN/AEconazole
About EconazoleSynthetic Imidazole derivative, Antifungal.Mechanism of Action of EconazoleEconazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.Pharmacokinets of EconazoleAbsorption:It is minimally absorbed after topical application.Onset of Action for EconazoleN/ADuration of Action for EconazoleN/AHalf Life of EconazoleN/ASide Effects of Econazole1.Burning
2.Pruritis
3.Stinging
4.Erythema
Contra-indications of EconazoleHypersensitivity to EconazoleSpecial Precautions while taking Econazole1.Use medication as directed for entire period of treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Econazole1.Cutaneous candidiasis
2.Tinea pedis
3.Tinea cruris
4.Tinea versicolor
Interactions for EconazoleN/ATypical Dosage for EconazoleCutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily.
Tinea infection:Gently rub in to the affected area once daily.Schedule of EconazoleHStorage Requirements for EconazoleThe drug should be stored at 15 - 30 degree C.Effects of Missed Dosage of EconazoleApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of EconazoleGive supportive measures and treatment.
Triamcinolone acetonide
About Triamcinolone acetonideA synthetic glucocorticoid, Topical anti-inflammatory(steroidal).Mechanism of Action of Triamcinolone acetonideThe drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts more selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-a, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Triamcinolone acetonideAbsorption: Triamcinolone acetonide is absorbed after topical application. Distribution: It is distributed mainly in protein bound form. Metabolism: It is metabolized primarily in the liver. Excretion: It is excreted by the kidneys and small amount is excreted through bile also.Onset of Action for Triamcinolone acetonideN/ADuration of Action for Triamcinolone acetonideN/AHalf Life of Triamcinolone acetonideN/ASide Effects of Triamcinolone acetonide1.Burning
2.Itching
3.Irritation
4.Dryness
5.Folliculitis
6.Hypertrichosis
7.Acneiform eruptions
8.Hypopigmentation
9.Dermatitis
10.Secondary infection
11.Skin atrophy
Contra-indications of Triamcinolone acetonideHypersensitivity to Triamcinolone acetonideSpecial Precautions while taking Triamcinolone acetonide1.Occlusive dressingsPregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Triamcinolone acetonide1. Inflammations of corticosteroid-responsive dermatoses
2. Treatment of skin disorders: Dermatitis, Psoriasis
Interactions for Triamcinolone acetonideN/ATypical Dosage for Triamcinolone acetonideTopical application: Apply the cream on the affected area 2-4 times daily; depending on the severity of the condition. Schedule of Triamcinolone acetonideN/AStorage Requirements for Triamcinolone acetonideStore at room temperature at a range of 15 to 30 degree C. Protect from light and moisture. Keep out of reach of children.Effects of Missed Dosage of Triamcinolone acetonideApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Triamcinolone acetonideProvide symptomatic treatment and supportive measures.Home Delivery for Econazole + Triamcinolone acetonide in Your City
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Econazole + Triamcinolone acetonide is a generic medicine name and there are several brands available for it. Some of the brands for econazole + triamcinolone acetonide might be better known than econazole + triamcinolone acetonide itself. If the pharmacy that's willing to deliver medicines to your home doesn't have econazole + triamcinolone acetonide in stock, you can ask for one of the branded alternatives for econazole + triamcinolone acetonide.