Bromazepam Pharmacology

Bromazepam

About Bromazepam
Benzodiazepine derivative,Anxiolytic,Sedative,Hypnotic,Skeletal muscle relaxant
Mechanism of Action of Bromazepam
Bromazepam binds to the GABA receptor GABAA. These will facilitates GABA mediated chloride channel opening and produce hyperpolarisation.This will produce an increase in the concentration of inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neurons.These alter normal excitatory functions of the body.
Pharmacokinets of Bromazepam
Absorption: Absorbed after oral administration
Distribution: Protein binding is 70%
Metabolism: Metabolised in the liver
Excretion: Excreted through urine
Onset of Action for Bromazepam
2 to 3 hrs
Duration of Action for Bromazepam
8 to 12 hrs
Half Life of Bromazepam
12 to 20 hrs
Side Effects of Bromazepam
1.Dizziness
2.Headache
3.Drowsiness
4.Fatigue
5.Irritability
6.Confusion
7.Hallucination
8.Muscle weakness
Contra-indications of Bromazepam
1.Respiratory insufficiency
2.Hepatic insufficiency
3.Sleep apnea syndrome
4.Hypersensitivity.
Special Precautions while taking Bromazepam
1.Hypersensitivity to benzodiazepines
2.Closed angle glaucoma
3.Myasthenia gravis
4.Liver or kidney disease
5.Chronic lung disease
6.Epilepsy
7.Mental illness or depression
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Neonates: Contraindicated
Indications for Bromazepam
1.Anxiety
2.Preanaesthetic medication
3.Epigastric pain
4.Hypertension
5.Insomnia
Interactions for Bromazepam
Alcohol and other CNS depressants>>Enhanced CNS effect
Cemetidine,Disulfiram,Fluoxetine,Isoniazid,Ketoconazole,Propranalol,Propoxyphene,
Valproic Acid: Bromazepam activity enhanced
Digoxin,Imipiramine&Desipramine:Enhanced activity of these drugs
Levodopa:Decrease in antiparkinsonism efficacy
Typical Dosage for Bromazepam
3 mg twice or thrice daily, In Severe condition s up to 6 to 12 mg twice or thrice daily
Schedule of Bromazepam
H
Storage Requirements for Bromazepam
Store this medication at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat and light.Keep out of the reach of children

Effects of Missed Dosage of Bromazepam
N/A
Effects of Overdose of Bromazepam
N/A

Home Delivery for Bromazepam in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including bromazepam.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for bromazepam and other medicines and health products. Home delivery services for bromazepam may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take bromazepam only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for bromazepam before they complete the sale. You can get this information while placing the order for bromazepam with the pharmacy.

Bromazepam is a generic medicine name and there are several brands available for it. Some of the brands for bromazepam might be better known than bromazepam itself. If the pharmacy that's willing to deliver medicines to your home doesn't have bromazepam in stock, you can ask for one of the branded alternatives for bromazepam.