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- Pharmacology For Lycopene + Calcium + Selenium + Zinc + Amino acids
Lycopene + Calcium + Selenium + Zinc + Amino acids Pharmacology
Lycopene + Calcium + Selenium + Zinc + Amino acids
About Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AMechanism of Action of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/APharmacokinets of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AOnset of Action for Lycopene + Calcium + Selenium + Zinc + Amino acidsN/ADuration of Action for Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AHalf Life of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/ASide Effects of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AContra-indications of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/ASpecial Precautions while taking Lycopene + Calcium + Selenium + Zinc + Amino acidsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Lycopene + Calcium + Selenium + Zinc + Amino acids1.Pre-eclampsia
2.Infertility
3.Cancer
4.Atherosclerosis and CVD
Interactions for Lycopene + Calcium + Selenium + Zinc + Amino acidsN/ATypical Dosage for Lycopene + Calcium + Selenium + Zinc + Amino acids1 per daySchedule of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AStorage Requirements for Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AEffects of Missed Dosage of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/AEffects of Overdose of Lycopene + Calcium + Selenium + Zinc + Amino acidsN/ALycopene
About LycopeneCarotenoid;Terpenes and terpenoids, Dietary antioxidant.Mechanism of Action of LycopeneN/APharmacokinets of LycopeneN/AOnset of Action for LycopeneN/ADuration of Action for LycopeneN/AHalf Life of LycopeneN/ASide Effects of LycopeneN/AContra-indications of LycopeneN/ASpecial Precautions while taking LycopeneN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for LycopeneN/AInteractions for LycopeneN/ATypical Dosage for LycopeneN/ASchedule of LycopeneN/AStorage Requirements for LycopeneN/AEffects of Missed Dosage of LycopeneN/AEffects of Overdose of LycopeneN/ACalcium
About CalciumCalcium is necessary for cardiac function, muscle contraction, nervous activity, coagulation of blood and for maintaining structural integrity of cell membranes.
Plasma concentration of calcium is kept in normal range by three endocrine factors which control metabolism of calcium. These are (a) Parathyroid hormone, (b) Calcitonin, (c) Vitamin D. Calcium in plasma is bound to albumin, is complexed with anions (e.g. phosphate) and as diffusible ionic calcium. The physiological effects are exerted by ionic calcium. The predominant source of calcium is dairy products and the daily intake varies from 200 - 2500 mg. Adequate calcium intake is particularly important during periods of bone growth in childhood and adolescence and during pregnancy and lactation.
Patients with advanced renal insufficiency exhibit phosphate retention and some degree of hyperphosphataemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy and soft tissue calcification. Calcium acetate, when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the faeces.
Deficiency signs and symptoms: Osteoporosis, pathological fractures, brittle nails and hair.Mechanism of Action of CalciumCalcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and
A-V conduction. Calcium is also required for blood-coagulation.
Pharmacokinets of CalciumAbsorption: Actively absorbed from gastrointestinal tract in an ionized form; and vitamin D in it`s active form is required for calcium absorption, Distribution: Distributed mainly in to skeletal tissue (99%) and 1% is distributed equally between the intracellular and extra cellular fluid. CSF levels are about half of the serum calcium levels, Metabolism: Not significantly metabolized in the body, Excretion: Excreted mainly through faeces and a small amount is excreted through urine.Onset of Action for CalciumN/ADuration of Action for CalciumN/AHalf Life of CalciumN/ASide Effects of Calcium1.Constipation
2.Bloating
3.Excess gas
4.Anorexia
5.Nausea
6.Vomiting
7.Abdominal pain
8.Thirst
9.Hypercalcaemia
10.Polyuria
11.Dry mouth
12.Delirium
13.Confusion
Contra-indications of Calcium1.Renal calculi
2.Hypophosphataemia
3.Hypercalcaemia
4.Ventricular fibrillation.
Special Precautions while taking Calcium1.Renal impairment
2.Cardiac diseases
3.Sarcoidosis
4.Cor pulmonale
5.Respiratory acidosis
6.Respiratory failure
7.End stage renal failure
8.Hypoparathyroid patients
9.Digitalized patients
10.Prolonged use of therapeutic amounts.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Calcium1.Hypocalcaemia
2.Calcium and vitamin D deficiency
3.Calcium deficiency during pregnancy and lactation
4.Rickets
5.Prevention of osteoporosis in postmenopausal women
6.Chronic renal failure.
Interactions for CalciumN/ATypical Dosage for CalciumOral: 500mg to 2g daily in two to four divided doses.
Hypocalcaemia:
Adults: 1g daily. Increases to 2g daily if required.
Prevention of osteoporosis: 1 to 1.5g daily.
Children: 45 to 65mg/kg daily.
Neonates: 50 to 150mg/kg and should not exceed 1g.
Schedule of CalciumN/AStorage Requirements for CalciumStore in a well closed container in a cool and dry place. Protect from light.
Effects of Missed Dosage of CalciumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CalciumRemove calcium from stomach by induced emesis and gastric lavage. Provide symptomatic treatment and supportive measures.Selenium
About SeleniumA vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.Mechanism of Action of SeleniumN/APharmacokinets of SeleniumN/AOnset of Action for SeleniumN/ADuration of Action for SeleniumN/AHalf Life of SeleniumN/ASide Effects of SeleniumN/AContra-indications of SeleniumN/ASpecial Precautions while taking SeleniumN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for SeleniumN/AInteractions for SeleniumN/ATypical Dosage for SeleniumN/ASchedule of SeleniumN/AStorage Requirements for SeleniumN/AEffects of Missed Dosage of SeleniumN/AEffects of Overdose of SeleniumN/AZinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresAmino acids
About Amino acidsAn amino acid is any molecule that contains both amine and carboxyl functional groups. These amino acids are the basic components of proteins. There are twenty standard amino acids used by cells in protein biosynthesis that are specified by the general genetic code.
Amino acids are joined to each other by peptide bonds. A peptide bond is a chemical bond formed between two molecules (carboxyl group of one molecule reacts with the amino group of the other molecule), releasing a molecule of water (H2O). The resulting CO-NH bond is called a peptide bond, the chemical bond that links the amino acid monomers in a protein chain. Each protein has its own unique amino acid sequence that is known as its primary structure. Amino acids can be linked together in varying sequences to form a huge variety of proteins. The unique shape of each protein determines its function in the body.
Aminoacids are of 2 types, essential and nonessential. Essential amino acids are the ones that must be obtained in the diet and non-essential are synthesized within the body
Essential aminoacids: Methionine, Threonine, Tryptophan, Valine, Isoleucine, Leucine, Lysine, Phenylalanine, Histidine,
Nonessential aminoacids: Alanine, Asparagine, Aspartic acids, Proline, Glutamic acid, Glutamine, Serine
Amino acids Arginine, Cysteine, Glycine and Tyrosine are considered conditionally essential, meaning they are not normally required in the diet, but must be supplied exogenously to specific populations that do not synthesize it in adequate amounts
Histidine and Arginine are generally only considered essential in children, because the metabolic pathways that synthesize these amino acids are not fully developed in children.
Nutritional role of aminoacids: Aminoacids have been used orally or in relatively dilute solutions intravenously as supplementary nutrients for patients unable to metabolize intact protein adequately. For patients in whom oral or tube feeding is contraindicated or Inadequate good nutrition may be achieved or maintained by intravenous feeding known as total parenteral nutrition or intravenous or parenteral hyperalimentation. Such feeding provides essential nutrients in a sufficiently concentrated form that does not exceed normal daily fluid requirements.
Mechanism of Action of Amino acidsN/APharmacokinets of Amino acidsN/AOnset of Action for Amino acidsN/ADuration of Action for Amino acidsN/AHalf Life of Amino acidsN/ASide Effects of Amino acidsN/AContra-indications of Amino acidsN/ASpecial Precautions while taking Amino acidsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Amino acids1.Hypoproteinaemia
2.Pre and post surgeryInteractions for Amino acidsN/ATypical Dosage for Amino acidsN/ASchedule of Amino acidsN/AStorage Requirements for Amino acidsN/AEffects of Missed Dosage of Amino acidsN/AEffects of Overdose of Amino acidsN/AHome Delivery for Lycopene + Calcium + Selenium + Zinc + Amino acids in Your City
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