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- Pharmacology For Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acids
Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acids Pharmacology
Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acids
About Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AMechanism of Action of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/APharmacokinets of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AOnset of Action for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/ADuration of Action for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AHalf Life of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/ASide Effects of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AContra-indications of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/ASpecial Precautions while taking Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsAntioxidantInteractions for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/ATypical Dosage for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acids1 capsule / daySchedule of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AStorage Requirements for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AEffects of Missed Dosage of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/AEffects of Overdose of Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acidsN/ABeta Carotene
About Beta CaroteneA natural precursor to Vitamin A.Mechanism of Action of Beta CaroteneBeta-carotene acts as the precursor of Vitamin A and in the body it is converted in to Vitamin A. Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.Pharmacokinets of Beta CaroteneAbsorption: Completely absorbed normally. Steatorrhoea, bile deficiency, and protein poor diet adversely affects the absorption and absorption requires bile salts, pancreatic lipase, and dietary fat.
Distribution: Stored primarily as palmitate in kupffer`s cells in liver. Circulates in the form of specific alpha-1 protein; retinol binding protein and transported to cellular retinol binding protein of target cells.
Metabolism: Metabolized in the liver.
Excretion: Excreted mainly through bile and a small amount is excreted through urine.
Onset of Action for Beta CaroteneN/ADuration of Action for Beta CaroteneN/AHalf Life of Beta CaroteneN/ASide Effects of Beta CaroteneAdverse effects occurs only with higher doses and toxicity
1. Nausea
2. Vomiting
3. Itching
4. Dermatitis
5. Exfoliation
6. Alopecia
7. Bone and joint pain
8. Anorexia
9. Irritability
10. Increased intracranial pressure
11. Hepatic impairment
12. Anaphylactic shock
Contra-indications of Beta Carotene1. Hypervitaminosis A
2. Hypersensitivity to Beta Carotene
Special Precautions while taking Beta Carotene1. Oral form should not use in patients with malabsorption syndrome.
2. In inadequate bile secretion oral route may be used with concurrent administration of bile salts.
3. I. V. route is contraindicated except for special water miscible forms intended for infusion with large parenteral volumes and should not use I. V. push of vitamin A of any type.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Beta Carotene1. Vitamin A deficiency
2. Xerophthalmia
3. Acne
4. Ichthyosis
5. Bitot`s spots
6. Night blindness
Interactions for Beta CaroteneCholestyramine: Absorption of Vitamin A is reduced due to reduced availability of fat stabilizing bile salts.
Mineral oil: Interferes with intestinal absorption of Vitamin A.
Oral Contraceptives: Plasma Vitamin A levels are significantly increased.Typical Dosage for Beta CaroteneSevere vitamin A deficiency with xerophthalmia: 500000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Severe vitamin A deficiency: 100000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Children: 5000 to 10000 IU daily for 14 days.
Schedule of Beta CaroteneC1 (Oral)
C (Parenteral)
Storage Requirements for Beta CaroteneStore in a well closed, airtight container in a cool dry place.Effects of Missed Dosage of Beta CaroteneTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Beta CaroteneDiscontinue the vitamin A if hypercalcaemia persists and administer I.V. saline, prednisolone, and calcitonin if required. Monitor hepatic function tests to detect liver damage. Spirulina
About SpirulinaEdible blue-green algae, Dietary supplement.Mechanism of Action of SpirulinaSpirulina exerts its action by being a richest food supplements. It is a good source of proteins (60 to 70%) and also contains vitamins, minerals, carbohydrates, lipids, fibres, organic nitrogen, antioxidants, phycocyanobilin etc. The protein content of Spirulina is 85 to 95% digestible. Fat content (5 to 7%) of Spirulina is in the form of essential fatty acids in the form of linolenic acid and gamma linolenic acid.
Gamma linolenic acid elevates HDL levels and improves fatty acid profile and act as a precursor of PGE1 which prevents platelet aggregation in blood vessels and also controls inflammations. It is a richest source of anti oxidants like superoxide dumatase enzyme and beta-carotene. It also contains high concentrations of B complex vitamins. Phycocyanobilin which is a linear tetrapyrrole related to haem forms Phycocyanin which forms soluble complexes with iron and other minerals and is in an easily absorbable form.
Pharmacokinets of SpirulinaN/AOnset of Action for SpirulinaN/ADuration of Action for SpirulinaN/AHalf Life of SpirulinaN/ASide Effects of SpirulinaNo known adverse effectsContra-indications of SpirulinaNo known contraindicationsSpecial Precautions while taking SpirulinaN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Spirulina1.Nutritional supplement
2.Antioxidant for preventing diseases caused by free radicals
3.Stimulant for thyroid gland
4.Stimulation of immune system and prostaglandin levels
5.Probiotic for building body`s resistance
6.Prevention of atherosclerosis
7.Prevention of platelet aggregation and dilation of blood vessels
8.Prevention of xerophthalmia, cataract, and night blindness
9.Therapeutic supplement in treatment of malignancy, pancreatitis, cirrhosis, hepatitis
10.Prophylaxis against precancerous lesions like oral leukoplakia and submucous fibrosis
11.Controle of diabetes
12.Dietary supplement in adults, sportsmen, growing and malnourished childrenInteractions for SpirulinaN/ATypical Dosage for SpirulinaOral: 1000mg 12th hourly for 2months; then 500mg 12th hourly for the following two months.Schedule of SpirulinaN/AStorage Requirements for SpirulinaN/AEffects of Missed Dosage of SpirulinaN/AEffects of Overdose of SpirulinaN/AMinerals
About MineralsDietary mineral supplement, Nutritional supplement.Mechanism of Action of MineralsN/APharmacokinets of MineralsN/AOnset of Action for MineralsN/ADuration of Action for MineralsN/AHalf Life of MineralsN/ASide Effects of MineralsN/AContra-indications of MineralsN/ASpecial Precautions while taking MineralsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for MineralsN/AInteractions for MineralsN/ATypical Dosage for MineralsN/ASchedule of MineralsN/AStorage Requirements for MineralsN/AEffects of Missed Dosage of MineralsN/AEffects of Overdose of MineralsN/AMultivitamins
About MultivitaminsDietary supplement, Vitamins.Mechanism of Action of MultivitaminsN/APharmacokinets of MultivitaminsN/AOnset of Action for MultivitaminsN/ADuration of Action for MultivitaminsN/AHalf Life of MultivitaminsN/ASide Effects of MultivitaminsN/AContra-indications of MultivitaminsN/ASpecial Precautions while taking MultivitaminsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for MultivitaminsN/AInteractions for MultivitaminsN/ATypical Dosage for MultivitaminsN/ASchedule of MultivitaminsN/AStorage Requirements for MultivitaminsN/AEffects of Missed Dosage of MultivitaminsN/AEffects of Overdose of MultivitaminsN/AVit B6
About Vit B6Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization.
Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.Mechanism of Action of Vit B6Vitamin B6 is a collective term for Pyridoxine, Pyridoxal, Pyridoxamine and their phosphorylated derivatives such as Pyridoxine phosphate, Pyridoxal phosphate and Pyridoxamine derivatives respectively. Vitamin B6 is essential for the metabolism of amino acid, glycogen and fatty acids, for nerve functions, for the formation of red blood cells and also helps the skin healthy. Vitamin B6 is also used for the synthesis of nucleic acid, Haemoglobin, Sphingomyelin, other Sphingolipids, Serotonin, Dopamine, Noradrenaline and GABA.Pharmacokinets of Vit B6Absorption: Vitamin B6 is readily absorbed after oral administration.
Distribution: It is mainly distributed in the body in protein bound form. It is stored primarily in the liver and to a lesser extent muscle and brain.
Metabolism: It is metabolised in the liver
Onset of Action for Vit B6N/ADuration of Action for Vit B6N/AHalf Life of Vit B615-20 daysSide Effects of Vit B61. Neuropathy
2. Unstable gait
3. Drowsiness
4. Perioral numbness
5. Paresthesia
6. Numbness of feet
7. Somnolence
8. Sensory neuropathy
9. Ataxia
Contra-indications of Vit B61. Hypersensitivity to Vitamin B6Special Precautions while taking Vit B6N/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Contraindicated
Indications for Vit B61. Vitamin B6 deficiency including inadequate diet and drug induced causes
2. Neuropathy
3. Premenstrual syndrome
4. Hyperoxaluria type 1
5. Metabolic disorder
6. Isoniazid poisoning
Interactions for Vit B6Cycloserine, Hydralazine, Isoniazide, Oral contraceptive, Penicillamine: Increase Pyridoxine requirement.
Levodopa: Pyridoxine reverses the therapeutic effect of Levodopa.
Phenobarbital, Phenytoin: Pyridoxine decreases serum level of these anticonvulsants.
Typical Dosage for Vit B6Adult: 10 - 20 mg / day
Dietary deficiency: 2.5 -10 mg / day for effective therapeutic response is obtained.
Maintenance dose: 2 - 5 mg / day for several weeks.
Drug induced deficiency: 100 - 200 mg / day for 3 weeks.
Maintenance dose: 25 - 100 mg / day
Neuropathy: 50 - 200 mg /day
Premenstrual syndrome: 40 - 500 mg / day
Hyperoxaluria type 1: 25 - 300 mg / day
Metabolic disorder: 100-500 mg /day.
Isoniazid poisoning: Initial dose: 1 - 4 g as IV administration, then 1 g IM every 30 minute until Pyridoxine dose is equal to the Isoniazid dose has been given.
Schedule of Vit B6N/AStorage Requirements for Vit B6Store it at 15 - 30 degree C. Protect from moisture and heat.Effects of Missed Dosage of Vit B6Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vit B6Give supportive measures and symptomatic treatment. The signs of Pyridoxine overdose can be resolved by discontinuation (withdrawal) of Pyridoxine.Amino acids
About Amino acidsAn amino acid is any molecule that contains both amine and carboxyl functional groups. These amino acids are the basic components of proteins. There are twenty standard amino acids used by cells in protein biosynthesis that are specified by the general genetic code.
Amino acids are joined to each other by peptide bonds. A peptide bond is a chemical bond formed between two molecules (carboxyl group of one molecule reacts with the amino group of the other molecule), releasing a molecule of water (H2O). The resulting CO-NH bond is called a peptide bond, the chemical bond that links the amino acid monomers in a protein chain. Each protein has its own unique amino acid sequence that is known as its primary structure. Amino acids can be linked together in varying sequences to form a huge variety of proteins. The unique shape of each protein determines its function in the body.
Aminoacids are of 2 types, essential and nonessential. Essential amino acids are the ones that must be obtained in the diet and non-essential are synthesized within the body
Essential aminoacids: Methionine, Threonine, Tryptophan, Valine, Isoleucine, Leucine, Lysine, Phenylalanine, Histidine,
Nonessential aminoacids: Alanine, Asparagine, Aspartic acids, Proline, Glutamic acid, Glutamine, Serine
Amino acids Arginine, Cysteine, Glycine and Tyrosine are considered conditionally essential, meaning they are not normally required in the diet, but must be supplied exogenously to specific populations that do not synthesize it in adequate amounts
Histidine and Arginine are generally only considered essential in children, because the metabolic pathways that synthesize these amino acids are not fully developed in children.
Nutritional role of aminoacids: Aminoacids have been used orally or in relatively dilute solutions intravenously as supplementary nutrients for patients unable to metabolize intact protein adequately. For patients in whom oral or tube feeding is contraindicated or Inadequate good nutrition may be achieved or maintained by intravenous feeding known as total parenteral nutrition or intravenous or parenteral hyperalimentation. Such feeding provides essential nutrients in a sufficiently concentrated form that does not exceed normal daily fluid requirements.
Mechanism of Action of Amino acidsN/APharmacokinets of Amino acidsN/AOnset of Action for Amino acidsN/ADuration of Action for Amino acidsN/AHalf Life of Amino acidsN/ASide Effects of Amino acidsN/AContra-indications of Amino acidsN/ASpecial Precautions while taking Amino acidsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Amino acids1.Hypoproteinaemia
2.Pre and post surgeryInteractions for Amino acidsN/ATypical Dosage for Amino acidsN/ASchedule of Amino acidsN/AStorage Requirements for Amino acidsN/AEffects of Missed Dosage of Amino acidsN/AEffects of Overdose of Amino acidsN/AHome Delivery for Beta Carotene + Spirulina + Minerals + Multivitamins + Vit B6 + Amino acids in Your City
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