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- Pharmacology For Beta Carotene + Lutein
Beta Carotene + Lutein Pharmacology
Beta Carotene + Lutein
About Beta Carotene + LuteinN/AMechanism of Action of Beta Carotene + LuteinN/APharmacokinets of Beta Carotene + LuteinN/AOnset of Action for Beta Carotene + LuteinN/ADuration of Action for Beta Carotene + LuteinN/AHalf Life of Beta Carotene + LuteinN/ASide Effects of Beta Carotene + LuteinN/AContra-indications of Beta Carotene + LuteinN/ASpecial Precautions while taking Beta Carotene + LuteinN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Beta Carotene + Lutein1. Vitamin A deficiency
2. Xerophthalmia
3. Bitot`s spots
4. Night blindness
Interactions for Beta Carotene + LuteinN/ATypical Dosage for Beta Carotene + LuteinOne capsule / daySchedule of Beta Carotene + LuteinN/AStorage Requirements for Beta Carotene + LuteinN/AEffects of Missed Dosage of Beta Carotene + LuteinN/AEffects of Overdose of Beta Carotene + LuteinN/ABeta Carotene
About Beta CaroteneA natural precursor to Vitamin A.Mechanism of Action of Beta CaroteneBeta-carotene acts as the precursor of Vitamin A and in the body it is converted in to Vitamin A. Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.Pharmacokinets of Beta CaroteneAbsorption: Completely absorbed normally. Steatorrhoea, bile deficiency, and protein poor diet adversely affects the absorption and absorption requires bile salts, pancreatic lipase, and dietary fat.
Distribution: Stored primarily as palmitate in kupffer`s cells in liver. Circulates in the form of specific alpha-1 protein; retinol binding protein and transported to cellular retinol binding protein of target cells.
Metabolism: Metabolized in the liver.
Excretion: Excreted mainly through bile and a small amount is excreted through urine.
Onset of Action for Beta CaroteneN/ADuration of Action for Beta CaroteneN/AHalf Life of Beta CaroteneN/ASide Effects of Beta CaroteneAdverse effects occurs only with higher doses and toxicity
1. Nausea
2. Vomiting
3. Itching
4. Dermatitis
5. Exfoliation
6. Alopecia
7. Bone and joint pain
8. Anorexia
9. Irritability
10. Increased intracranial pressure
11. Hepatic impairment
12. Anaphylactic shock
Contra-indications of Beta Carotene1. Hypervitaminosis A
2. Hypersensitivity to Beta Carotene
Special Precautions while taking Beta Carotene1. Oral form should not use in patients with malabsorption syndrome.
2. In inadequate bile secretion oral route may be used with concurrent administration of bile salts.
3. I. V. route is contraindicated except for special water miscible forms intended for infusion with large parenteral volumes and should not use I. V. push of vitamin A of any type.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Beta Carotene1. Vitamin A deficiency
2. Xerophthalmia
3. Acne
4. Ichthyosis
5. Bitot`s spots
6. Night blindness
Interactions for Beta CaroteneCholestyramine: Absorption of Vitamin A is reduced due to reduced availability of fat stabilizing bile salts.
Mineral oil: Interferes with intestinal absorption of Vitamin A.
Oral Contraceptives: Plasma Vitamin A levels are significantly increased.Typical Dosage for Beta CaroteneSevere vitamin A deficiency with xerophthalmia: 500000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Severe vitamin A deficiency: 100000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Children: 5000 to 10000 IU daily for 14 days.
Schedule of Beta CaroteneC1 (Oral)
C (Parenteral)
Storage Requirements for Beta CaroteneStore in a well closed, airtight container in a cool dry place.Effects of Missed Dosage of Beta CaroteneTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Beta CaroteneDiscontinue the vitamin A if hypercalcaemia persists and administer I.V. saline, prednisolone, and calcitonin if required. Monitor hepatic function tests to detect liver damage. Lutein
About LuteinCarotenoid, Xanthophyll, Dietary antioxidant.Mechanism of Action of LuteinN/APharmacokinets of LuteinN/AOnset of Action for LuteinN/ADuration of Action for LuteinN/AHalf Life of LuteinN/ASide Effects of LuteinN/AContra-indications of LuteinN/ASpecial Precautions while taking LuteinN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for LuteinN/AInteractions for LuteinN/ATypical Dosage for LuteinN/ASchedule of LuteinN/AStorage Requirements for LuteinN/AEffects of Missed Dosage of LuteinN/AEffects of Overdose of LuteinN/AHome Delivery for Beta Carotene + Lutein in Your City
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Beta Carotene + Lutein is a generic medicine name and there are several brands available for it. Some of the brands for beta carotene + lutein might be better known than beta carotene + lutein itself. If the pharmacy that's willing to deliver medicines to your home doesn't have beta carotene + lutein in stock, you can ask for one of the branded alternatives for beta carotene + lutein.