Co Enzyme Q10 Pharmacology
Co Enzyme Q10
CoQH2+ 2 FeIII-cytochrome c ? CoQ + 2 FeII-cytochrome c. main function of this transport is adenosine triphosphate production. Coenzyme Q10 also increases adenosine triphosphate levels by preventing the loss of the adenine nucleotide pool from cardiac cells. Coenzyme Q10 has activity as an antioxidant scavenger and an indirect stabilizer of calcium channels to decrease calcium overload. It also inhibits the oxidation of LDL-cholesterol. LDL-cholesterol oxidation is believed to play a significant role in the pathogenesis of atherosclerosis.
2. Vomiting
3. Stomach upset
4. Heartburn
5. Diarrhea
6. Loss of appetite
7. Skin itching
8. Rash
9. Insomnia
10. Headache
11. Dizziness
12. Irritability
13. Increased light sensitivity of the eyes
14. Fatigue
15. Flu-like symptoms
2. Antioxidant
3. Migraine headaches
4. Parkinson`s Disease
5. Mitochondrial Encephalomyopathies
6. Migraine
7. CHF
8. Hypertension
9. Diabetes
10. Cancer
Oral-
Mitochondrial cytopathies: 150 mg per day or 2 mg per kg per day with titration up to 3,000 mg per day in some patients
Parkinson`s disease: 300 to 1,200 mg per day in four divided doses
Cardiovascular problems: 50 to 200 mg per day
Migraine 100 to 200 mg per day
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