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- Pharmacology For Iron lll Hydroxide Polymaltose (IPC) + Folic acid
Iron lll Hydroxide Polymaltose (IPC) + Folic acid Pharmacology
Iron lll Hydroxide Polymaltose (IPC) + Folic acid
About Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AMechanism of Action of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/APharmacokinets of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AOnset of Action for Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/ADuration of Action for Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AHalf Life of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/ASide Effects of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AContra-indications of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/ASpecial Precautions while taking Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AInteractions for Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/ATypical Dosage for Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/ASchedule of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AStorage Requirements for Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AEffects of Missed Dosage of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AEffects of Overdose of Iron lll Hydroxide Polymaltose (IPC) + Folic acidN/AIron lll Hydroxide Polymaltose (IPC)
About Iron lll Hydroxide Polymaltose (IPC)It is a water soluble iron oxide, macro molecular complex of poly nuclear iron (III) hydroxide and partially hydrolysed dextrin (polymaltose).
Mechanism of Action of Iron lll Hydroxide Polymaltose (IPC)The absorption of ferric iron from IPC is controlled by a feedback mechanism. When IPC comes in contact with the iron binding sides at the mucosal surface, a physiological exchange is assumed to occur. IPC releases the required amount of ferric iron, which is actively transported into the mucosal cell by a carrier protein and from there released for binding to ferritin or transferrin.Pharmacokinets of Iron lll Hydroxide Polymaltose (IPC)N/AOnset of Action for Iron lll Hydroxide Polymaltose (IPC)N/ADuration of Action for Iron lll Hydroxide Polymaltose (IPC)N/AHalf Life of Iron lll Hydroxide Polymaltose (IPC)N/ASide Effects of Iron lll Hydroxide Polymaltose (IPC)There is a very low incidence of adverse effects. Occasionally gastrointestinal symptoms such as sensation of repletion, pressure in the epigastric reagion, nausea, constipation or diarrhoea can occur.Contra-indications of Iron lll Hydroxide Polymaltose (IPC)N/ASpecial Precautions while taking Iron lll Hydroxide Polymaltose (IPC)N/APregnancy Related InformationMay be used.Old Age Related InformationMay be used.Breast Feeding Related InformationMay be used.Children Related InformationN/AIndications for Iron lll Hydroxide Polymaltose (IPC)Treatment of latent iron deficiency and iron deficiency anaemia. Prevention of iron and folic acid deficiency before, during and after pregnancy. For prophylatic therapy of iron deficiency to cover the recommended daily dietary allowence during pregnancy and lactation.
Interactions for Iron lll Hydroxide Polymaltose (IPC)N/ATypical Dosage for Iron lll Hydroxide Polymaltose (IPC)Dosage and duration of therapy are dependent upon the extent of iron deficiency. It should be taken during or immediately after meals.Schedule of Iron lll Hydroxide Polymaltose (IPC)N/AStorage Requirements for Iron lll Hydroxide Polymaltose (IPC)Store at room temperature.Protect from heat and light.Keep out of the reach of children.Effects of Missed Dosage of Iron lll Hydroxide Polymaltose (IPC)Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Iron lll Hydroxide Polymaltose (IPC)Relatively non toxic. Provide symptomatic treatment and supportive measures.Folic Acid
About Folic AcidDietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.Mechanism of Action of Folic AcidFolic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.Pharmacokinets of Folic AcidAbsorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic AcidOral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic AcidOral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic AcidN/ASide Effects of Folic AcidN/AContra-indications of Folic AcidN/ASpecial Precautions while taking Folic Acid1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Folic Acid1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic AcidOral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic AcidC1 (Oral)
C (Parenteral)
Storage Requirements for Folic AcidStore at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.Effects of Missed Dosage of Folic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Folic AcidRelatively non toxic. Provide symptomatic treatment and supportive measures.Home Delivery for Iron lll Hydroxide Polymaltose (IPC) + Folic acid in Your City
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Iron lll Hydroxide Polymaltose (IPC) + Folic acid is a generic medicine name and there are several brands available for it. Some of the brands for iron lll hydroxide polymaltose (ipc) + folic acid might be better known than iron lll hydroxide polymaltose (ipc) + folic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron lll hydroxide polymaltose (ipc) + folic acid in stock, you can ask for one of the branded alternatives for iron lll hydroxide polymaltose (ipc) + folic acid.