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- Pharmacology For Iron (Ferrous sulphate) + Vitamin B-Complex
Iron (Ferrous sulphate) + Vitamin B-Complex Pharmacology
Iron (Ferrous sulphate) + Vitamin B-Complex
About Iron (Ferrous sulphate) + Vitamin B-ComplexN/AMechanism of Action of Iron (Ferrous sulphate) + Vitamin B-ComplexN/APharmacokinets of Iron (Ferrous sulphate) + Vitamin B-ComplexN/AOnset of Action for Iron (Ferrous sulphate) + Vitamin B-ComplexN/ADuration of Action for Iron (Ferrous sulphate) + Vitamin B-ComplexN/AHalf Life of Iron (Ferrous sulphate) + Vitamin B-ComplexN/ASide Effects of Iron (Ferrous sulphate) + Vitamin B-ComplexN/AContra-indications of Iron (Ferrous sulphate) + Vitamin B-ComplexN/ASpecial Precautions while taking Iron (Ferrous sulphate) + Vitamin B-ComplexN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Iron (Ferrous sulphate) + Vitamin B-ComplexN/AInteractions for Iron (Ferrous sulphate) + Vitamin B-ComplexN/ATypical Dosage for Iron (Ferrous sulphate) + Vitamin B-ComplexN/ASchedule of Iron (Ferrous sulphate) + Vitamin B-ComplexN/AStorage Requirements for Iron (Ferrous sulphate) + Vitamin B-ComplexN/AEffects of Missed Dosage of Iron (Ferrous sulphate) + Vitamin B-ComplexN/AEffects of Overdose of Iron (Ferrous sulphate) + Vitamin B-ComplexN/AIron (Ferrous sulphate)
About Iron (Ferrous sulphate)Oral iron preparation, Antianemic,hematinic.Mechanism of Action of Iron (Ferrous sulphate)Ferrous sulfate is used as a source of iron for iron-deficiency anaemia. It is given by mouth; the dried form is often used in solid dosage forms and the heptahydrate in liquid dosage forms. Usual doses of dried ferrous sulfate are up to 600 mg daily (equivalent to 180 to 195 mg of iron daily,).
Ferrous sulfate oxidised with nitric and sulfuric acids yields ferric subsulfate solution, also known as Monsel`s solution, which has been used as a haemostatic. It exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Pharmacokinets of Iron (Ferrous sulphate)Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed. Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin. Metabolism: Iron liberated by destruction of haemoglobin is reused by the body. Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.Onset of Action for Iron (Ferrous sulphate)N/ADuration of Action for Iron (Ferrous sulphate)N/AHalf Life of Iron (Ferrous sulphate)N/ASide Effects of Iron (Ferrous sulphate)1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations.
Contra-indications of Iron (Ferrous sulphate)1.Haemolytic anaemia unless iron deficiency anaemia is also present
2.Haemochromatosis
3.Haemosiderosis
4.Peptic ulcer
5.Regional enteritis
6.Ulcerative colitis
7.Those receiving repeated blood transfusions.
Special Precautions while taking Iron (Ferrous sulphate)1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related InformationMay be usedOld Age Related InformationUse with cautionBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Iron (Ferrous sulphate)1. Iron deficiency
2. Iron deficiency anaemiaInteractions for Iron (Ferrous sulphate)N/ATypical Dosage for Iron (Ferrous sulphate)Adults: 100 to 300mg; twice daily. Increases the dosage based on patient`s response if required up to 300mg 4 times daily.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Schedule of Iron (Ferrous sulphate)HStorage Requirements for Iron (Ferrous sulphate)Store in a well closed container in a cool dry place. Protect from light.Effects of Missed Dosage of Iron (Ferrous sulphate)Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Iron (Ferrous sulphate)Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl. Vitamin B-Complex
About Vitamin B-ComplexVitamin B-complex are group of vitamins, which include Thiamine (B1),Riboflavin (B2),Niacin (B3),Pantothenic acid (B5),Pyridoxine (B6),Cyanocobalamin (B12),Folic acid and Biotin.
These vitamins are essential for the breakdown of carbohydrates into glucose (this provides energy for the body),the breakdown of fats and proteins (which aids the normal functioning of the nervous system),muscle tone in the stomach and intestinal tract,Skin,Hair,Eyes,Mouth and Liver
Mechanism of Action of Vitamin B-ComplexN/APharmacokinets of Vitamin B-ComplexN/AOnset of Action for Vitamin B-ComplexN/ADuration of Action for Vitamin B-ComplexN/AHalf Life of Vitamin B-ComplexN/ASide Effects of Vitamin B-Complex1.Drowsiness
2.Headache
3.Diarrhoea
4.Nausea.
5.Numbness of the skin
Contra-indications of Vitamin B-ComplexHypersensitivity to the ingredient of Vitamin B-complexSpecial Precautions while taking Vitamin B-Complex1.Pernecious anaemia
2.Patient receiving dialysisPregnancy Related InformationMay be used.Old Age Related InformationMay be used.Breast Feeding Related InformationMay be used.Children Related InformationMay be used.Indications for Vitamin B-Complex1.Vitamin deficiency states
2. As an adjuvant to antibiotic therapy
3. Combinations with lactobacillus are indicated in aphthous stomatitis, thrush.Interactions for Vitamin B-ComplexSulfinpyrazone: Uricosuric effect of sulfinpyrazone may be inhibited by niacin.
Levodopa: Pyridoxine reduces efficacy of levodopa. Avoid supplemental vitamins that contain greater then 5 mg pyridoxine in the daily dose.
Phenobarbital: Serum levels of Phenobarbital may be decreased if used concomitantly with pyridoxine.
Phenytoin: Pyridoxine decreases serum levels of phenytoin.
Dapsone: PABA antagonizes anti-malarial effect of dapsone.
Typical Dosage for Vitamin B-ComplexI tablet /daySchedule of Vitamin B-ComplexN/AStorage Requirements for Vitamin B-ComplexStore at room temperature. Keep out of the reach of children.Protect from heat, light and moisture.Effects of Missed Dosage of Vitamin B-ComplexTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin B-ComplexGive supportive measures and symptomatic treatment.Home Delivery for Iron (Ferrous sulphate) + Vitamin B-Complex in Your City
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