Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal) Pharmacology

Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)

About Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
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Mechanism of Action of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Pharmacokinets of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Onset of Action for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Duration of Action for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Half Life of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Side Effects of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Contra-indications of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Special Precautions while taking Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Pregnancy Related Information
Contraindicated;since Betamethasone and Neomycin are contraindicated in pregnancy
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated;since Betamethasone and Neomycin are contraindicated in breast feeding
Children Related Information
N/A
Indications for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
Nasal allergy
Interactions for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Typical Dosage for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
Instill 1 - 2 drops to the affected nose 1 - 3 times daily
Schedule of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Storage Requirements for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Effects of Missed Dosage of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A
Effects of Overdose of Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal)
N/A

Betamethasone (Nasal)

About Betamethasone (Nasal)
Glucocorticoid steroid, seasonal or perennial allergic and nonallergic (vasomotor) .
Mechanism of Action of Betamethasone (Nasal)
Betamethasone exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.Betamethasone can be given as a nasal spray to treat and prevent the inflammation that can occur in conditions such as allergies.
Pharmacokinets of Betamethasone (Nasal)
N/A
Onset of Action for Betamethasone (Nasal)
N/A
Duration of Action for Betamethasone (Nasal)
N/A
Half Life of Betamethasone (Nasal)
N/A
Side Effects of Betamethasone (Nasal)

1.Bronchospasm
2.Epistaxis
3.Smell and taste disturbances
4.Irritation of the tissues in the nose
5.Dryness of the nose and throat
6.Local sensitivity reactions
Contra-indications of Betamethasone (Nasal)
1.Perforated ear drum
2.After nasal surgery
3.Tuberculosis
Special Precautions while taking Betamethasone (Nasal)
1.Glaucoma
2.Herpes-type infection of the eye infection
3.Recent nasal surgery
4.Nasal sores
5.Liver disease
6.Tuberculosis
7.Underactive thyroid
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Betamethasone (Nasal)
1.Otitis externa
2.Non-allergic rhinitis
Interactions for Betamethasone (Nasal)
N/A
Typical Dosage for Betamethasone (Nasal)
Appy the medicament as directed by the Physician
Schedule of Betamethasone (Nasal)
N/A
Storage Requirements for Betamethasone (Nasal)
Store this medication at room temperature away from moisture and heat.Keep out of the reach of children.
Effects of Missed Dosage of Betamethasone (Nasal)
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Betamethasone (Nasal)
Give supportive measures and symptomatic treatment.

Naphazoline

About Naphazoline
Imidazoline derivative,Alpha-adrenergic agonist, A decongestant,vasoconstrictor.
Mechanism of Action of Naphazoline
Naphazoline exerts its vasoconstrictor action by acting as a selective alpha-1 adrenergic agonist. Thus it reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion.
Pharmacokinets of Naphazoline
Absorption:It is well absorbed intranasally
Onset of Action for Naphazoline
10minutes
Duration of Action for Naphazoline
2 - 6 hours
Half Life of Naphazoline
N/A
Side Effects of Naphazoline
1.Rebound nasal congestion
2.Sneezing
3.Stinging
4.Dryness of mucosa
Contra-indications of Naphazoline
Hypersensitivity to Naphazoline
Special Precautions while taking Naphazoline
1.Prolonged use
2.Untreated nasal infection
3.Hyperthyroidism
4.Cardiac diseases
5.Hypertension
6.Diabetic mellitus
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Naphazoline
Nasal congestion
Interactions for Naphazoline
N/A
Typical Dosage for Naphazoline
Adult:
Instil 1 -2 drops of or sprays into the nostrils whenever necessary. Dose can be repeated every 3 - 6 hours if needed up to 5 days.
Children:
Above 12years: same as adult dose
6 - 12 years: 1- 2 drops or sprays into the nostrils as needed
Schedule of Naphazoline
N/A
Storage Requirements for Naphazoline
Store at room temperature in a tightly closed container. Keep away from children.
Effects of Missed Dosage of Naphazoline
Instil the missed dose of nasal drop in to the nostrils as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Naphazoline
Provide supportive measures and symptomatic treatment.

Neomycin (Nasal)

About Neomycin (Nasal)
An aminoglycoside, Antibiotic in bacterial infections of nose.
Mechanism of Action of Neomycin (Nasal)
This aminoglycoside cause protein synthesis inhibition by "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically Neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.
Pharmacokinets of Neomycin (Nasal)
N/A
Onset of Action for Neomycin (Nasal)
N/A
Duration of Action for Neomycin (Nasal)
N/A
Half Life of Neomycin (Nasal)
N/A
Side Effects of Neomycin (Nasal)
1.Irritation
2.Dryness
3.Sneezing
4.Headache
5.Lightheadedness
6.Itching
7.Feeling sick
8.Nose bleeds
9.Loss of smell
Contra-indications of Neomycin (Nasal)
1.Hypersensitivity to Neomycin
2.Fungal infections of the nose
Special Precautions while taking Neomycin (Nasal)
Prolonged use
Pregnancy Related Information
contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
contraindicated
Children Related Information
Use with caution
Indications for Neomycin (Nasal)
Bacterial infection of the nose
Interactions for Neomycin (Nasal)
N/A
Typical Dosage for Neomycin (Nasal)
2 - 3 drops instilled into the each nostrils 2 - 3 times a day.
Schedule of Neomycin (Nasal)
N/A
Storage Requirements for Neomycin (Nasal)
Stored at controlled room temperature. Protect from light and excessive heat. Keep out of reach of children.
Effects of Missed Dosage of Neomycin (Nasal)
Instil the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Neomycin (Nasal)
Give supportive measures and symptomatic treatment.

Home Delivery for Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal) in Your City

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Betamethasone (Nasal) + Naphazoline + Neomycin (Nasal) is a generic medicine name and there are several brands available for it. Some of the brands for betamethasone (nasal) + naphazoline + neomycin (nasal) might be better known than betamethasone (nasal) + naphazoline + neomycin (nasal) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have betamethasone (nasal) + naphazoline + neomycin (nasal) in stock, you can ask for one of the branded alternatives for betamethasone (nasal) + naphazoline + neomycin (nasal).