Oxymetazoline Pharmacology

Oxymetazoline

About Oxymetazoline
Alpha Adrenergic Agonist, Imidazoline Derivative, Vasoconstrictor (nasal decongestant).
Mechanism of Action of Oxymetazoline
It is a nasal decongestant with selective alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion
Pharmacokinets of Oxymetazoline
Absorption: Administered intranasally, occasional systemic absorption may occur.
Onset of Action for Oxymetazoline
Nasal: 5 to 10 minutes

Duration of Action for Oxymetazoline
Nasal: Below12hours

Half Life of Oxymetazoline
N/A
Side Effects of Oxymetazoline
1. Dryness of nose and throat
2. Irritation
3. Burning sensation
4. Stinging
5. Sneezing
6. Rebound congestion
7. Hypertension
Contra-indications of Oxymetazoline
1. Hypersensitivity to the drug
2. Glaucoma
Special Precautions while taking Oxymetazoline
1. Type 2 diabetes mellitus
2. Dry membranes in nose
3. Enlarged prostate
4. Crdiovascular diseases
5. Hyperthyroidism
6. Hypertension
7. Along with MAO inhibitors
8. 0. 05% solution is contraindicated in children below 6 years and use 0. 01% solution in children below 2 years
9. Avoid prolonged use







Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Oxymetazoline
1.Nasal congestion
Interactions for Oxymetazoline
N/A
Typical Dosage for Oxymetazoline
Nasal congestion:
Adults and children over 6 years: Apply 2 to 3 drops or sprays of 0.05% solution in each nostril every 10 to 12 hours. Should not use; more than 3 to 5 days.
Children (below 6 years): Apply 1 to 3 drops of 0.025% solution in each nostril every 6 to 12 hours. Should not use; more than 3 to 5 days.
Infants: Apply 1 to 2 drops of 0.01% solution in each nostril every 8 to 12 hours under medical supervision. Should not use; more than 3 to 5 days.

Schedule of Oxymetazoline
H
Storage Requirements for Oxymetazoline
Store at room temperature at a range of 15 to 30 degree C. Protect from direct heat and light. Avoid freezing. Keep out of reach of children.
Effects of Missed Dosage of Oxymetazoline
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Oxymetazoline
Provide supportive treatment and symptomatic measures.

Home Delivery for Oxymetazoline in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including oxymetazoline.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for oxymetazoline and other medicines and health products. Home delivery services for oxymetazoline may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take oxymetazoline only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for oxymetazoline before they complete the sale. You can get this information while placing the order for oxymetazoline with the pharmacy.

Oxymetazoline is a generic medicine name and there are several brands available for it. Some of the brands for oxymetazoline might be better known than oxymetazoline itself. If the pharmacy that's willing to deliver medicines to your home doesn't have oxymetazoline in stock, you can ask for one of the branded alternatives for oxymetazoline.