Dutasteride Pharmacology

Dutasteride

About Dutasteride
A 5-alpha-reductase inhibitor, In benign prostatic hyperplasia(BPH),male baldness.
Mechanism of Action of Dutasteride
This is a selective inhibitor of both type 1 and type 2 isoforms of steroid 5alpha-reductase (an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone which influences the development of prostate gland). This decreasing level of this hormone relieves the symptoms associated with benign prostatic hyperplasia.
Pharmacokinets of Dutasteride
Absorption - Moderately absorbed after oral administration
Distribution- Widely distributed in the body as protein binding (99%) form
Metabolism- Metabolized in the liver.
Excretion- Excreted via fecal route
Onset of Action for Dutasteride
N/A
Duration of Action for Dutasteride
N/A
Half Life of Dutasteride
5 weeks
Side Effects of Dutasteride
1. Inability to have or maintain an erection
2. Decrease in sex drive
3. Difficulty ejaculating
4. Breast tenderness or enlargement
Contra-indications of Dutasteride
1. Hypersensitivity to the drug
2. Cancer of the prostate
3. Liver disease
4. Problems with urination
Special Precautions while taking Dutasteride
1.Dutasteride is intended for use by men only.
2.Take each dose with a full glass of water.
3.Swallow the capsules whole. Do not chew, crush or break the capsules

Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Dutasteride
1. Benign prostatic hyperplasia (BPH)
2. Male pattern baldness
Interactions for Dutasteride
N/A
Typical Dosage for Dutasteride
Oral-
Adults-
For benign prostatic hyperplasia- 0.5 milligram (mg) once a day
Schedule of Dutasteride
N/A
Storage Requirements for Dutasteride
Store at room temperature (25 degree C) away from light and moisture
Effects of Missed Dosage of Dutasteride
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Dutasteride
Give symptomatic and supportive treatment

Home Delivery for Dutasteride in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dutasteride.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dutasteride and other medicines and health products. Home delivery services for dutasteride may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take dutasteride only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dutasteride before they complete the sale. You can get this information while placing the order for dutasteride with the pharmacy.

Dutasteride is a generic medicine name and there are several brands available for it. Some of the brands for dutasteride might be better known than dutasteride itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dutasteride in stock, you can ask for one of the branded alternatives for dutasteride.