Sodium Picosulphate Pharmacology

Sodium Picosulphate

About Sodium Picosulphate
A locally acting Bowel preparation, A stimulant laxative.
Mechanism of Action of Sodium Picosulphate
Sodium picosulphate is a stimulant laxative. After oral administration it is activated by the bacteria present in the large intestine. It then stimulates nerve endings in the intestinal wall. Stimulation of nerves contracts the muscles in the intestine and rectum with more force (peristalsis) and the bowel can be emptied, and hence relieves constipation. Sodium picosulphate is also used to stimulate the emptying of the bowel before surgery, childbirth or medical investigation of the gut.
Pharmacokinets of Sodium Picosulphate
Absorption: Sodium picosulphate is well absorbed after oral administration.
Distribution: It is mainly distributed in the colon.
Metabolism: It undergoes hydrolysis in the colon by colonic bacteria into its active form.
Excretion: It is excreted mainly through faeces.
Onset of Action for Sodium Picosulphate
6 - 12 hours
Duration of Action for Sodium Picosulphate
N/A
Half Life of Sodium Picosulphate
N/A
Side Effects of Sodium Picosulphate
1. Diarrhoea
2. Abdominal discomfort
Contra-indications of Sodium Picosulphate
1. Intestinal obstruction
2. Severe dehydration
3. Appendicitis
4. Ulcerative colitis
5. Crohn`s disease
6. Abdominal cramps
7. Hypersensitivity to Sodium picosulphate
Special Precautions while taking Sodium Picosulphate
1. Irritable bowel syndrome
2. Lower abdominal pain
3. Prolonged us
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Below 4years : Contraindicated
Indications for Sodium Picosulphate
1. Emptying the bowel prior to surgery, childbirth or radiological investigation of the gut.
2. Short term management of constipation.

Interactions for Sodium Picosulphate
Sodium picosulphate is broken down by bacteria in the large intestine so it is possible that patients taking broad spectrum antibiotics may experience some loss of laxative action.
Typical Dosage for Sodium Picosulphate
Adult: Initial dose: 5 - 15 mg maximum dose: 60 mg
Drops: solution contains 1mg of sodium picosulphate / ml solution
Adult: 7 - 12 drops
Children above 3 years: 2 - 7drops daily




Schedule of Sodium Picosulphate
N/A
Storage Requirements for Sodium Picosulphate
Store in a cool, dry place, away from direct light and heat. Keep out of the reach of children
Effects of Missed Dosage of Sodium Picosulphate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sodium Picosulphate
Give supportive measures and symptomatic treatment.

Home Delivery for Sodium Picosulphate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sodium picosulphate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sodium picosulphate and other medicines and health products. Home delivery services for sodium picosulphate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sodium picosulphate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sodium picosulphate before they complete the sale. You can get this information while placing the order for sodium picosulphate with the pharmacy.

Sodium Picosulphate is a generic medicine name and there are several brands available for it. Some of the brands for sodium picosulphate might be better known than sodium picosulphate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sodium picosulphate in stock, you can ask for one of the branded alternatives for sodium picosulphate.