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- Pharmacology For Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + Dicyclomine
Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + Dicyclomine Pharmacology
Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + Dicyclomine
About Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AMechanism of Action of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/APharmacokinets of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AOnset of Action for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/ADuration of Action for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AHalf Life of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/ASide Effects of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AContra-indications of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/ASpecial Precautions while taking Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationLactation: Contraindicated;since Dicyclomine is contraindicated in breast feeding mother, the combination generic cannot be used in lactation.Children Related InformationN/AIndications for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineThis preparation contains antacids Aluminium hydroxide and Magnesium hydroxide, antiflatulent Simethicone and antispasmodic Dicyclomine.
1. Gastro intestinal upset
2. Hyperacidity
3. Abdominal spasm
Interactions for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/ATypical Dosage for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + Dicyclomine1 tablet to be taken with each meal and at bed time.Schedule of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AStorage Requirements for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AEffects of Missed Dosage of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AEffects of Overdose of Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + DicyclomineN/AAluminium Hydroxide
About Aluminium HydroxideAntacid,Antidote,Protectant( Topical), In hyperacidity; hyperphosphatemia.Mechanism of Action of Aluminium HydroxideIt neutralizes and reduces stomach acid relieving heartburn (acid reflux, GERD) and indigestion. This results increased pH and reduce the pepsin activity. It also binds to the phosphate in the gut and form a nonsoluble nonabsorbable aluminium phosphate complex.Pharmacokinets of Aluminium HydroxideAbsorption- Poorly absorbed.Excretion- Excreted through feces and breast milkOnset of Action for Aluminium HydroxideN/ADuration of Action for Aluminium Hydroxide20 to 180minutesHalf Life of Aluminium HydroxideN/ASide Effects of Aluminium Hydroxide1. Loss of appetite
2. Constipation
3. Hypophosphatemia
4. Osteomalacia
5. Confusion
6. Unusual tiredness or discomfort
7. Muscle weakness
8. Encephalopathy
Contra-indications of Aluminium Hydroxide1. Hypersensitivity to the drug
2. Renal failure
3. Hypertension
4. Heart disease
5. Kidney disease
6. Gastrointestinal bleeding.
Special Precautions while taking Aluminium Hydroxide1. Stomach problems
2. Allergies
Pregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Aluminium Hydroxide1. Gastric hyperacidity
2. Ulcers
3. Digestive disorders
4. Hyperphosphatemia
5. Oesophagitis
6. Hiatal hernia
7. Gastritis
Interactions for Aluminium HydroxideN/ATypical Dosage for Aluminium HydroxideOral-
Acidity and Hyperphosphatemia -
Adult-
500-1500mg tablet or capsule 1 hr after meals and at bed time
5 to 30 ml suspension1 hr after meals and at bed time as needed
Schedule of Aluminium HydroxideN/AStorage Requirements for Aluminium HydroxideStore it at room temperature and away from excess heat and moisture. Refrigerate the suspension. Do not freeze.Effects of Missed Dosage of Aluminium HydroxideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Aluminium HydroxideGive symptomatic and supportive treatmentMagnesium Hydroxide
About Magnesium HydroxideMineral, Magnesium compound, Antacid and laxative.Mechanism of Action of Magnesium HydroxideIt neutralize the gastric acid (where the hydroxide ions from the Mg(OH)2 combine with acidic H+ ions produced in the form of hydrochloric acid by parietal cells in the stomach). This relieves the hyperacidity problems in the stomach.Pharmacokinets of Magnesium HydroxideN/AOnset of Action for Magnesium HydroxideN/ADuration of Action for Magnesium HydroxideN/AHalf Life of Magnesium HydroxideN/ASide Effects of Magnesium Hydroxide1. Stomach cramps
2. Upset stomach
3. Vomiting
4. Diarrhea
5. Black/tarry stools
6. Rectal bleeding.
7. Constipation
8. Loss of appetite
9. Unusual tiredness
10. Muscle weakness
11. Hypermagnesaemia
12. Renal failure
Contra-indications of Magnesium Hydroxide1. Hypersensitivity to the drug
2. Kidney disease
3. Stomach/abdominal pain
4. Nausea
5. Vomiting
Special Precautions while taking Magnesium Hydroxide1. Colostomy
2. Dehydration
3. Diarrhea
4. Intestinal problems like colitis
5.Do not take any other medication within 1 to 2 hours of taking this medication.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationLess than 6 Years : ContraindicatedIndications for Magnesium Hydroxide1. Constipation
2. Peptic ulcer
3. Hiatal herniaInteractions for Magnesium HydroxideN/ATypical Dosage for Magnesium HydroxideOral-
Adult-
Antacid:
Tab-500mg to 1.5g daily.
Liquid-5-15ml daily.
Laxative:
Tab-2.4-4.8g daily.
Liquid -30-60ml daily.
Schedule of Magnesium HydroxideN/AStorage Requirements for Magnesium HydroxideStore it at room temperature (15-30 degree C) and away from excess heat and moisture.Effects of Missed Dosage of Magnesium HydroxideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Magnesium HydroxideGive symptomatic and supportive treatment.Simethicone
About SimethiconeOral anti-foaming agent, Silicones, Antiflatulent.Mechanism of Action of SimethiconeThis anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.Pharmacokinets of SimethiconeExcretion- Excreted through feces.Onset of Action for SimethiconeN/ADuration of Action for SimethiconeN/AHalf Life of SimethiconeN/ASide Effects of Simethicone1. Bloating
2. Constipation
3. Diarrhea
4. Gas
5. Heartburn
Contra-indications of Simethicone1. Hypersensitivity to the drug
2. Liver disease
3. Kidney disease
4. Serious illness
Special Precautions while taking Simethicone1.Swallow the tablets and capsules with a full glass of water.
2.Chew the chewable tablets thoroughly before swallowing.
3.Shake the drops well before using them.
4.To make administration easier, the drops can be mixed with 30 ml (2 tablespoons) of water or another liquid.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Simethicone1. Abdominal pain which is due to excessive gas in the digestive tract
2. Before gastroscopy or radiography of the bowel
Interactions for SimethiconeN/ATypical Dosage for SimethiconeOral-
Adults and teenagers-
60 -125mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Chewable tablets:
Adults and teenagers-
40 -125 mg four times a day, after meals and at bedtime or 150 mg three times a day, after meals. Not more than 500 mg should be taken in twenty-four hours.
Suspension:
Adults and teenagers-
40 -95 mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Schedule of SimethiconeN/AStorage Requirements for SimethiconeStored at room temperature (15-30?C) away from moisture and heat.Effects of Missed Dosage of SimethiconeTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of SimethiconeGive symptomatic and supportive treatment.Dicyclomine
About DicyclomineAnticholinergic ,Antimuscarinic, Antispasmodic and in urinary incontinence.Mechanism of Action of DicyclomineDicyclomine is an anticholinergic drug. It exerts its action by inhibiting muscarinic (((cholinergic))) receptors on smooth muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. It inhibits gastrointestinal propulsive motility and reduces gastric acid secretion. It also has a direct relaxant effect on smooth muscle. It readily crosses the blood brain barrier and produces CNS effects.Pharmacokinets of DicyclomineAbsorption: About 70 % of the drug is absorbed after oral administration.
Distribution: It is extensively distributed in tissue mainly in protein bound (((99%))) form. It readily crosses blood brain barrier.
Metabolism: Dicyclomine undergoes hepatic metabolism
Excretion: It is excreted mainly in the urine and small amount in the faeces.
Onset of Action for Dicyclomine1-2 hours.Duration of Action for Dicyclomine4-6 hours.Half Life of Dicyclomine1.8 hours (((initial phase))). 9 - 10 hours (((secondary phase)))Side Effects of Dicyclomine1.Constipation
2.Dry mouth
3.Nausea
4.Vomiting
5.Abdominal discomfort
6.Headache
7.Dizziness
8.Confusion
9.Palpitations
10.Tachycardia
11.Increased intraocular pressure
12.Mydriasis
13.Urine retention
14.Urinary hesitancy
15.Decreased sweating
Contra-indications of Dicyclomine1.Hypersensitivity to Dicyclomine and other anticholinergic drugs
2.Narrow angle glaucoma
3.Obstructive gastro intestinal tract
4.Obstructive uropathy
5.Reflux oesophagitis
6.Severe ulcerative colitis
7.Myasthenia gravis
8.Unstable cardiovascular status in acute haemorrhage
Special Precautions while taking Dicyclomine1.Renal impairment
2.Hepatic impairment
3.Heart failure
4.Prostatic hypertrophy
5.Hiatus hernia associated
6.Hyperthyroidism
7.Autonomic neuropathy
8.Ulcerative colitis
9.Arrhythmia
10.Hypertension
11.Coronary artery disease
Pregnancy Related InformationUse with caution.Old Age Related InformationUse with caution.Breast Feeding Related InformationContraindicatedChildren Related InformationUse with caution.
NEONATES: contraindicatedIndications for Dicyclomine1. Irritable bowel syndrome
2.Colicky pain
Interactions for DicyclomineN/ATypical Dosage for DicyclomineAdult:
Oral: 80 mg / day in 4 divided doses 30 - 60 minutes before meals. Depending on the patient`s response dose can be increased to 160 mg / day in 4 divided doses after 1 week.
Children:
Infant colic: 5 - 10 mg every 6 - 8 hours, 15 minutes before each feed; dose is depending on the patient`s response and age.
Schedule of DicyclomineHStorage Requirements for DicyclomineStore at 15 - 30 degree C in a tightly closed container. Protect from light.Keep out of the reach of children
Effects of Missed Dosage of DicyclomineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DicyclomineGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal. Physostigmine is given to block the overdose symptoms of Dicyclomine.Home Delivery for Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + Dicyclomine in Your City
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Aluminium Hydroxide + Magnesium Hydroxide + Simethicone + Dicyclomine is a generic medicine name and there are several brands available for it. Some of the brands for aluminium hydroxide + magnesium hydroxide + simethicone + dicyclomine might be better known than aluminium hydroxide + magnesium hydroxide + simethicone + dicyclomine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have aluminium hydroxide + magnesium hydroxide + simethicone + dicyclomine in stock, you can ask for one of the branded alternatives for aluminium hydroxide + magnesium hydroxide + simethicone + dicyclomine.