Menthol + Methyl salicylate + Camphor Pharmacology

Menthol + Methyl salicylate + Camphor

About Menthol + Methyl salicylate + Camphor

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Mechanism of Action of Menthol + Methyl salicylate + Camphor

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Pharmacokinets of Menthol + Methyl salicylate + Camphor

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Onset of Action for Menthol + Methyl salicylate + Camphor

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Duration of Action for Menthol + Methyl salicylate + Camphor

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Half Life of Menthol + Methyl salicylate + Camphor

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Side Effects of Menthol + Methyl salicylate + Camphor

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Contra-indications of Menthol + Methyl salicylate + Camphor

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Special Precautions while taking Menthol + Methyl salicylate + Camphor

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Menthol + Methyl salicylate + Camphor

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Interactions for Menthol + Methyl salicylate + Camphor

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Typical Dosage for Menthol + Methyl salicylate + Camphor

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Schedule of Menthol + Methyl salicylate + Camphor

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Storage Requirements for Menthol + Methyl salicylate + Camphor

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Effects of Missed Dosage of Menthol + Methyl salicylate + Camphor

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Effects of Overdose of Menthol + Methyl salicylate + Camphor

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Menthol

About Menthol

Terpenes and terpenoid, Antipruritic, decongestant, topical analgesic.

Mechanism of Action of Menthol

Menthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and mild local anaesthetic effect relieves itching. It has good soothing effect and acts as a demulcent. It also acts as a carminative.

Pharmacokinets of Menthol

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Onset of Action for Menthol

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Duration of Action for Menthol

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Half Life of Menthol

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Side Effects of Menthol

1.Irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
12.Contact dermatitis
13.Allergic reactions

Contra-indications of Menthol

1. Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin

Special Precautions while taking Menthol

1.Should not apply Menthol directly in to or near the nostrils of small children or asthma patients
2.Prolonged use
3.Seizures
4.Should not take steam inhalation orally

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution
below 2 years: Contraindicated

Indications for Menthol

1. Rubefacient.
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5.Sore throat
6.Cold sores
7.Hay fever
8.As an inhalant to relieve nasal, bronchial, or upper respiratory congestion
9.Sinusitis
10.Bronchial cough
11.Pharyngeal inflammation

Interactions for Menthol

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Typical Dosage for Menthol

Dosage individualized based on requirements of the patient.
Lozenges: Dissolve lozenge (5%-10% menthol) slowly in the mouth hourly as needed by the patients.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Menthol (3.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1tsp of solution for each pint, up to thrice daily

Schedule of Menthol

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Storage Requirements for Menthol

Store at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.

Effects of Missed Dosage of Menthol

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Menthol

Provide symptomatic treatment and supportive measures.

Methyl salicylate

About Methyl salicylate

Salicylates, Rubefacient, counterirritant.

Mechanism of Action of Methyl salicylate

Methyl salicylate is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.

Pharmacokinets of Methyl salicylate

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Onset of Action for Methyl salicylate

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Duration of Action for Methyl salicylate

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Half Life of Methyl salicylate

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Side Effects of Methyl salicylate

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Contra-indications of Methyl salicylate

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Special Precautions while taking Methyl salicylate

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Methyl salicylate

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Interactions for Methyl salicylate

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Typical Dosage for Methyl salicylate

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Schedule of Methyl salicylate

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Storage Requirements for Methyl salicylate

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Effects of Missed Dosage of Methyl salicylate

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Effects of Overdose of Methyl salicylate

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Camphor

About Camphor

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Mechanism of Action of Camphor

Camphor acts as a rubefacient when it is rubbed on the skin and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and a mild local anaesthetic effect and relieves itching. When ingested in small amounts, it creates feelings of warmth and comfort in the epigastrium. Camphor acts as a local anesthetic on the respiratory passageways and causing cough suppression.

Pharmacokinets of Camphor

Absorption: Well absorbed through the skin, Distribution: Widely distributed in the body and crosses the placenta, Metabolism: Metabolized in liver, Excretion: Excreted mainly through urine and a minor portion is excreted through lungs.

Onset of Action for Camphor

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Duration of Action for Camphor

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Half Life of Camphor

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Side Effects of Camphor

1.Gastric irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole

Contra-indications of Camphor

1.Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin

Special Precautions while taking Camphor

1.Should not apply camphor directly in to or near the nostrils of small children or asthma patients
2.Prolonged use may lead to accumulation in adipose tissue
3.Seizures.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution
Children (below 2 years): Contraindicated

Indications for Camphor

1.Rubefacient
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5. As balm for chapped lips, cold sores
6.As an inhalant to relieve nasal, bronchial or upper respiratory congestion.

Interactions for Camphor

N/A

Typical Dosage for Camphor

Dosage individualized based on requirement and condition of the patient.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Camphor (6.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1 tsp of solution for each pint, up to thrice daily.

Schedule of Camphor

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Storage Requirements for Camphor

Store at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.

Effects of Missed Dosage of Camphor

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Camphor

Provide symptomatic treatment and supportive measures.
Ingestion: If camphor has been ingested recently, and the condition of the patient allows, perform gastric lavage. If only small amounts have been ingested, administer cathartics.
Inhalation: If camphor has been inhaled, remove patient from exposure, administer fresh air or oxygen, and establish respiration.
Topical: If there has been external contact with camphor, wash skin thoroughly with soap and water. Irrigate eyes with plenty of water.
In severe poisoning: Assist respiration in respiratory depression. Perform artificial respiration if required. Treat convulsions with diazepam or other suitable drugs. Protect the airway by endotracheal intubation or suitable measures, Perform gastric lavage and reduce absorption by administration of activated charcoal, and then a saline cathartic if required. Resin and charcoal haemoperfusion may be used in severe cases.

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